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C4P0A5

- C4P0A5_HUMAN

UniProt

C4P0A5 - C4P0A5_HUMAN

Protein
Submitted name:

Disrupted in schizophrenia 1 isoform 17

Gene

DISC1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (07 Jul 2009)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Disrupted in schizophrenia 1 isoform 17Imported
    Submitted name:
    Disrupted in schizophrenia 1 isoform 32Imported
    Gene namesi
    Name:DISC1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA27342.

    Structurei

    3D structure databases

    ProteinModelPortaliC4P0A5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK16534.

    Family and domain databases

    InterProiIPR026081. DISC1.
    [Graphical view]
    PANTHERiPTHR14332. PTHR14332. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C4P0A5-1 [UniParc]FASTAAdd to Basket

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    MPGGGPQGAP AAAGGGGVSH RAGSRDCLPP AACFRRRRLA RRPGYMRSST    50
    GPGIGFLSPA VGTLFRFPGG VSGEESHHSE SRARQCGLDS RGLLVRSPVS 100
    KSAAAPTVTS VRGTSAHFGI QLRGGTRLPD RLSWPCGPGS AGWQQEFAAM 150
    DSSETLDASW EAACSDGARR VRAAGSLPSA ELSSNSCSPG CGPEVPPTPP 200
    GSHSAFTSSF SFIRLSLGSA GERGEAEGCP PSREAESHCQ SPQEMGAKAA 250
    SLDGPHEDPR CLSRPFSLLA TRVSADLAQA ARNSSRPERD MHSLPDMDPG 300
    SSSSLDPSLA GCGGDGSSGS GDAHSWDTLL RKWEPVLRDC LLRNRRQMEV 350
    ISLRLKLQKL QEDAVENDDY DKAETLQQRL EDLEQEKISL HFQLPSRQPA 400
    LSSFLGHLAA QVQAALRRGA TQQASGDDTH TPLRMEPRLL EPTAQDSLHV 450
    SITRRDWLLQ EKQQLQKEIE ALQARMFVLE AKDQQLRREI EEQEQQLQWQ 500
    GCDLTPLVGQ LSLGQLQEVS KALQDTLASA GQIPFHAEPP ETIRRKPFLD 550
    G 551
    Length:551
    Mass (Da):59,299
    Last modified:July 7, 2009 - v1
    Checksum:i23BC3EE366CD87A0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FJ804188 mRNA. Translation: ACR40054.1.
    FJ804202 mRNA. Translation: ACR40068.1.
    RefSeqiNP_001158020.1. NM_001164548.1.
    UniGeneiHs.13318.

    Genome annotation databases

    GeneIDi27185.
    KEGGihsa:27185.
    UCSCiuc010pwt.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FJ804188 mRNA. Translation: ACR40054.1 .
    FJ804202 mRNA. Translation: ACR40068.1 .
    RefSeqi NP_001158020.1. NM_001164548.1.
    UniGenei Hs.13318.

    3D structure databases

    ProteinModelPortali C4P0A5.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 27185.
    KEGGi hsa:27185.
    UCSCi uc010pwt.1. human.

    Organism-specific databases

    CTDi 27185.
    PharmGKBi PA27342.

    Phylogenomic databases

    KOi K16534.

    Miscellaneous databases

    GenomeRNAii 27185.
    NextBioi 50024.

    Family and domain databases

    InterProi IPR026081. DISC1.
    [Graphical view ]
    PANTHERi PTHR14332. PTHR14332. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms."
      Nakata K., Lipska B.L., Hyde T.M., Ye T., Newburn E.N., Morita Y., Vakkalanka R., Barenboim M., Sei Y., Weinberger D.R., Kleinman J.E.
      Proc. Natl. Acad. Sci. U.S.A. 106:15873-15878(2009)
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Novel Fetal DISC1 Splice Variants Are Upregulated in Schizophrenia and Associated with Risk Polymorphisms."
      Nakata K., Lipska B.K., Hyde T.M., Ye T., Fink E.N., Morita Y., Vakkalanka R., Barenboim M., Sei Y., Weinberger D.R., Kleinman J.E.
      Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiC4P0A5_HUMAN
    AccessioniPrimary (citable) accession number: C4P0A5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 7, 2009
    Last sequence update: July 7, 2009
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.