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C4P098

- C4P098_HUMAN

UniProt

C4P098 - C4P098_HUMAN

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Protein
Submitted name:

Disrupted in schizophrenia 1 isoform 10

Gene

DISC1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Disrupted in schizophrenia 1 isoform 10Imported
Gene namesi
Name:DISC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27342.

Structurei

3D structure databases

ProteinModelPortaliC4P098.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK16534.

Family and domain databases

InterProiIPR026081. DISC1.
IPR009053. Prefoldin.
[Graphical view]
PANTHERiPTHR14332. PTHR14332. 1 hit.
SUPFAMiSSF46579. SSF46579. 1 hit.

Sequencei

Sequence statusi: Complete.

C4P098-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MPGGGPQGAP AAAGGGGVSH RAGSRDCLPP AACFRRRRLA RRPGYMRSST
60 70 80 90 100
GPGIGFLSPA VGTLFRFPGG VSGEESHHSE SRARQCGLDS RGLLVRSPVS
110 120 130 140 150
KSAAAPTVTS VRGTSAHFGI QLRGGTRLPD RLSWPCGPGS AGWQQEFAAM
160 170 180 190 200
DSSETLDASW EAACSDGARR VRAAGSLPSA ELSSNSCSPG CGPEVPPTPP
210 220 230 240 250
GSHSAFTSSF SFIRLSLGSA GERGEAEGCP PSREAESHCQ SPQEMGAKAA
260 270 280 290 300
SLDGPHEDPR CLSRPFSLLA TRVSADLAQA ARNSSRPERD MHSLPDMDPG
310 320 330 340 350
SSSSLDPSLA GCGGDGSSGS GDAHSWDTLL RKWEPVLRDC LLRNRRQMEV
360 370 380 390 400
ISLRLKLQKL QEDAVENDDY DKAETLQQRL EDLEQEKISL HFQLPSRQPA
410 420 430 440 450
LSSFLGHLAA QVQAALRRGA TQQASGDDTH TPLRMEPRLL EPTAQDSLHV
460 470 480 490 500
SITRRDWLLQ EKQQLQKEIE ALQARMFVLE AKDQQLRREI EEQEQQLQWQ
510 520 530 540 550
GCDLTPLVGQ LSLGQLQEVS KALQDTLASA GQIPFHAEPP ETIRSLQERI
560 570 580 590 600
KSLNLSLKEI TTKVCMSEKF CSTLRKKVND IETQLPALLE AKMHAISGNH
610 620 630 640 650
FWTAKDLTEE IRSLTSEREG LEGLLSKLLV LSSRNVKKLG SVKEDYNRLR
660 670 680 690 700
REVEHQETAY ETSVKENTMK YMETLKNKLC SCKCPLLGKV WEADLEACRL
710 720 730 740 750
LIQSLQLQEA RGSLSVEDER QMDDLEGAAP PIPPRLHSED KRKTPLKVLE
760 770 780 790 800
EWKTHLIPSL HCAGGEQKEV CPFHMASRGD PYSKGCFGTM LQMGTINIGK

ASH
Length:803
Mass (Da):87,777
Last modified:July 7, 2009 - v1
Checksum:i7F85A2BDA22E2F24
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ804181 mRNA. Translation: ACR40047.1.
RefSeqiNP_001158010.1. NM_001164538.1.
UniGeneiHs.13318.

Genome annotation databases

GeneIDi27185.
KEGGihsa:27185.
UCSCiuc009xfr.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ804181 mRNA. Translation: ACR40047.1 .
RefSeqi NP_001158010.1. NM_001164538.1.
UniGenei Hs.13318.

3D structure databases

ProteinModelPortali C4P098.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 27185.
KEGGi hsa:27185.
UCSCi uc009xfr.3. human.

Organism-specific databases

CTDi 27185.
PharmGKBi PA27342.

Phylogenomic databases

KOi K16534.

Miscellaneous databases

GenomeRNAii 27185.
NextBioi 50024.

Family and domain databases

InterProi IPR026081. DISC1.
IPR009053. Prefoldin.
[Graphical view ]
PANTHERi PTHR14332. PTHR14332. 1 hit.
SUPFAMi SSF46579. SSF46579. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms."
    Nakata K., Lipska B.L., Hyde T.M., Ye T., Newburn E.N., Morita Y., Vakkalanka R., Barenboim M., Sei Y., Weinberger D.R., Kleinman J.E.
    Proc. Natl. Acad. Sci. U.S.A. 106:15873-15878(2009)
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Novel Fetal DISC1 Splice Variants Are Upregulated in Schizophrenia and Associated with Risk Polymorphisms."
    Nakata K., Lipska B.K., Hyde T.M., Ye T., Fink E.N., Morita Y., Vakkalanka R., Barenboim M., Sei Y., Weinberger D.R., Kleinman J.E.
    Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiC4P098_HUMAN
AccessioniPrimary (citable) accession number: C4P098
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: October 1, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.