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C4P096

- C4P096_HUMAN

UniProt

C4P096 - C4P096_HUMAN

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Protein
Submitted name: Disrupted in schizophrenia 1 isoform 8
Gene
DISC1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Disrupted in schizophrenia 1 isoform 8Imported
Gene namesi
Name:DISC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PRIDEiC4P096.

Structurei

3D structure databases

ProteinModelPortaliC4P096.

Family & Domainsi

Phylogenomic databases

KOiK16534.

Family and domain databases

InterProiIPR026081. DISC1.
IPR009053. Prefoldin.
[Graphical view]
PANTHERiPTHR14332. PTHR14332. 1 hit.
SUPFAMiSSF46579. SSF46579. 1 hit.

Sequencei

Sequence statusi: Complete.

C4P096-1 [UniParc]FASTAAdd to Basket

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MPGGGPQGAP AAAGGGGVSH RAGSRDCLPP AACFRRRRLA RRPGYMRSST    50
GPGIGFLSPA VGTLFRFPGG VSGEESHHSE SRARQCGLDS RGLLVRSPVS 100
KSAAAPTVTS VRGTSAHFGI QLRGGTRLPD RLSWPCGPGS AGWQQEFAAM 150
DSSETLDASW EAACSDGARR VRAAGSLPSA ELSSNSCSPG CGPEVPPTPP 200
GSHSAFTSSF SFIRLSLGSA GERGEAEGCP PSREAESHCQ SPQEMGAKAA 250
SLDGPHEDPR CLSRPFSLLA TRVSADLAQA ARNSSRPERD MHSLPDMDPG 300
SSSSLDPSLA GCGGDGSSGS GDAHSWDTLL RKWEPVLRDC LLRNRRQMEV 350
ISLRLKLQKL QEDAVENDDY DKVETGFHYV GQAGLELLTS SNPPASASQS 400
AGITAETLQQ RLEDLEQEKI SLHFQLPSRQ PALSSFLGHL AAQVQAALRR 450
GATQQASGDD THTPLRMEPR LLEPTAQDSL HVSITRRDWL LQEKQQLQKE 500
IEALQARMFV LEAKDQQLRR EIEEQEQQLQ WQGCDLTPLV GQLSLGQLQE 550
VSKALQDTLA SAGQIPFHAE PPETIRSLQE RIKSLNLSLK EITTKVCMSE 600
KFCSTLRKKV NDIETQLPAL LEAKMHAISG NHFWTAKDLT EEIRSLTSER 650
EGLEGLLSKL LVLSSRNVKK LGSVKEDYNR LRREVEHQET AYETSVKENT 700
MKYMETLKNK LCSCKCPLLG KVWEADLEAC RLLIQSLQLQ EARGSLSVED 750
ERQMDDLEGA APPIPPRLHS EDKRKTPLKV LEEWKTHLIP SLHCAGGEQK 800
EESYILSAEL GEKCEDIGKK LLYLEDQLHT AIHSHDEDLI QSLRRELQMV 850
KETLQAMILQ LQPAKEAGER EAAASCMTAG VHEAQA 886
Length:886
Mass (Da):96,783
Last modified:July 7, 2009 - v1
Checksum:iBA975D556FA14B5A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FJ804179 mRNA. Translation: ACR40045.1.
RefSeqiNP_001158009.1. NM_001164537.1.
UniGeneiHs.13318.

Genome annotation databases

GeneIDi27185.
KEGGihsa:27185.
UCSCiuc010pxh.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FJ804179 mRNA. Translation: ACR40045.1 .
RefSeqi NP_001158009.1. NM_001164537.1.
UniGenei Hs.13318.

3D structure databases

ProteinModelPortali C4P096.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi C4P096.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 27185.
KEGGi hsa:27185.
UCSCi uc010pxh.2. human.

Organism-specific databases

CTDi 27185.

Phylogenomic databases

KOi K16534.

Miscellaneous databases

GenomeRNAii 27185.
NextBioi 50024.

Family and domain databases

InterProi IPR026081. DISC1.
IPR009053. Prefoldin.
[Graphical view ]
PANTHERi PTHR14332. PTHR14332. 1 hit.
SUPFAMi SSF46579. SSF46579. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms."
    Nakata K., Lipska B.L., Hyde T.M., Ye T., Newburn E.N., Morita Y., Vakkalanka R., Barenboim M., Sei Y., Weinberger D.R., Kleinman J.E.
    Proc. Natl. Acad. Sci. U.S.A. 106:15873-15878(2009)
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Novel Fetal DISC1 Splice Variants Are Upregulated in Schizophrenia and Associated with Risk Polymorphisms."
    Nakata K., Lipska B.K., Hyde T.M., Ye T., Fink E.N., Morita Y., Vakkalanka R., Barenboim M., Sei Y., Weinberger D.R., Kleinman J.E.
    Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiC4P096_HUMAN
AccessioniPrimary (citable) accession number: C4P096
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: January 22, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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