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C4P096

- C4P096_HUMAN

UniProt

C4P096 - C4P096_HUMAN

Protein
Submitted name:

Disrupted in schizophrenia 1 isoform 8

Gene

DISC1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (07 Jul 2009)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Disrupted in schizophrenia 1 isoform 8Imported
    Gene namesi
    Name:DISC1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    PTM / Processingi

    Proteomic databases

    PRIDEiC4P096.

    Structurei

    3D structure databases

    ProteinModelPortaliC4P096.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    KOiK16534.

    Family and domain databases

    InterProiIPR026081. DISC1.
    IPR009053. Prefoldin.
    [Graphical view]
    PANTHERiPTHR14332. PTHR14332. 1 hit.
    SUPFAMiSSF46579. SSF46579. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C4P096-1 [UniParc]FASTAAdd to Basket

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    MPGGGPQGAP AAAGGGGVSH RAGSRDCLPP AACFRRRRLA RRPGYMRSST    50
    GPGIGFLSPA VGTLFRFPGG VSGEESHHSE SRARQCGLDS RGLLVRSPVS 100
    KSAAAPTVTS VRGTSAHFGI QLRGGTRLPD RLSWPCGPGS AGWQQEFAAM 150
    DSSETLDASW EAACSDGARR VRAAGSLPSA ELSSNSCSPG CGPEVPPTPP 200
    GSHSAFTSSF SFIRLSLGSA GERGEAEGCP PSREAESHCQ SPQEMGAKAA 250
    SLDGPHEDPR CLSRPFSLLA TRVSADLAQA ARNSSRPERD MHSLPDMDPG 300
    SSSSLDPSLA GCGGDGSSGS GDAHSWDTLL RKWEPVLRDC LLRNRRQMEV 350
    ISLRLKLQKL QEDAVENDDY DKVETGFHYV GQAGLELLTS SNPPASASQS 400
    AGITAETLQQ RLEDLEQEKI SLHFQLPSRQ PALSSFLGHL AAQVQAALRR 450
    GATQQASGDD THTPLRMEPR LLEPTAQDSL HVSITRRDWL LQEKQQLQKE 500
    IEALQARMFV LEAKDQQLRR EIEEQEQQLQ WQGCDLTPLV GQLSLGQLQE 550
    VSKALQDTLA SAGQIPFHAE PPETIRSLQE RIKSLNLSLK EITTKVCMSE 600
    KFCSTLRKKV NDIETQLPAL LEAKMHAISG NHFWTAKDLT EEIRSLTSER 650
    EGLEGLLSKL LVLSSRNVKK LGSVKEDYNR LRREVEHQET AYETSVKENT 700
    MKYMETLKNK LCSCKCPLLG KVWEADLEAC RLLIQSLQLQ EARGSLSVED 750
    ERQMDDLEGA APPIPPRLHS EDKRKTPLKV LEEWKTHLIP SLHCAGGEQK 800
    EESYILSAEL GEKCEDIGKK LLYLEDQLHT AIHSHDEDLI QSLRRELQMV 850
    KETLQAMILQ LQPAKEAGER EAAASCMTAG VHEAQA 886
    Length:886
    Mass (Da):96,783
    Last modified:July 7, 2009 - v1
    Checksum:iBA975D556FA14B5A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FJ804179 mRNA. Translation: ACR40045.1.
    RefSeqiNP_001158009.1. NM_001164537.1.
    UniGeneiHs.13318.

    Genome annotation databases

    GeneIDi27185.
    KEGGihsa:27185.
    UCSCiuc010pxh.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FJ804179 mRNA. Translation: ACR40045.1 .
    RefSeqi NP_001158009.1. NM_001164537.1.
    UniGenei Hs.13318.

    3D structure databases

    ProteinModelPortali C4P096.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi C4P096.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 27185.
    KEGGi hsa:27185.
    UCSCi uc010pxh.2. human.

    Organism-specific databases

    CTDi 27185.

    Phylogenomic databases

    KOi K16534.

    Miscellaneous databases

    GenomeRNAii 27185.
    NextBioi 50024.

    Family and domain databases

    InterProi IPR026081. DISC1.
    IPR009053. Prefoldin.
    [Graphical view ]
    PANTHERi PTHR14332. PTHR14332. 1 hit.
    SUPFAMi SSF46579. SSF46579. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms."
      Nakata K., Lipska B.L., Hyde T.M., Ye T., Newburn E.N., Morita Y., Vakkalanka R., Barenboim M., Sei Y., Weinberger D.R., Kleinman J.E.
      Proc. Natl. Acad. Sci. U.S.A. 106:15873-15878(2009)
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Novel Fetal DISC1 Splice Variants Are Upregulated in Schizophrenia and Associated with Risk Polymorphisms."
      Nakata K., Lipska B.K., Hyde T.M., Ye T., Fink E.N., Morita Y., Vakkalanka R., Barenboim M., Sei Y., Weinberger D.R., Kleinman J.E.
      Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiC4P096_HUMAN
    AccessioniPrimary (citable) accession number: C4P096
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 7, 2009
    Last sequence update: July 7, 2009
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.