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Protein
Submitted name:

Ubiquitin-conjugating enzyme family protein

Gene

EHI_070750

Organism
Entamoeba histolytica
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

LigaseSAAS annotation

Keywords - Biological processi

Ubl conjugation pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin-conjugating enzyme family proteinImported
Gene namesi
ORF Names:EHI_070750Imported, EHI_083560Imported
OrganismiEntamoeba histolyticaImported
Taxonomic identifieri5759 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba
ProteomesiUP000001926 Componenti: Partially assembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi5759.rna_EHI_083560-1.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4GPRX-ray1.60A1-148[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.UniRule annotation

Phylogenomic databases

KOiK06689.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4M5T2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMRRIQKEL REIQQDPPCN CSAGPVGDDI FHWTATITGP DDSPYQGGLF
60 70 80 90 100
FLDVHFPVDY PFKAPRVTFM TKVYHPNINK NGVICLDILK DQWSPALTLS
110 120 130 140
RVLLSISSLL TDPNPSDPLD PEVANVLRAN KKQFEDTARE WTRMYARP
Length:148
Mass (Da):16,831
Last modified:July 7, 2009 - v1
Checksum:i1DD179CFDB003139
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS571388 Genomic DNA. Translation: EAL47305.1.
DS571284 Genomic DNA. Translation: EAL49024.1.
RefSeqiXP_652691.1. XM_647599.1.
XP_654416.1. XM_649324.2.

Genome annotation databases

EnsemblProtistsirna_EHI_070750-1; rna_EHI_070750-1; EHI_070750.
rna_EHI_083560-1; rna_EHI_083560-1; EHI_083560.
GeneIDi3407002.
3408716.
KEGGiehi:EHI_070750.
ehi:EHI_083560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS571388 Genomic DNA. Translation: EAL47305.1.
DS571284 Genomic DNA. Translation: EAL49024.1.
RefSeqiXP_652691.1. XM_647599.1.
XP_654416.1. XM_649324.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4GPRX-ray1.60A1-148[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5759.rna_EHI_083560-1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsirna_EHI_070750-1; rna_EHI_070750-1; EHI_070750.
rna_EHI_083560-1; rna_EHI_083560-1; EHI_083560.
GeneIDi3407002.
3408716.
KEGGiehi:EHI_070750.
ehi:EHI_083560.

Phylogenomic databases

KOiK06689.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 30459 / HM-1:IMSSImported.
  2. Lorenzi H., Amedeo P., Inman J., Schobel S., Caler E.
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: ATCC 30459 / HM-1:IMSSImported.
  3. "Structural determinants of ubiquitin conjugation in Entamoeba histolytica."
    Bosch D.E., Siderovski D.P.
    J. Biol. Chem. 288:2290-2302(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS).

Entry informationi

Entry nameiC4M5T2_ENTHI
AccessioniPrimary (citable) accession number: C4M5T2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: June 24, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.