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C4M5H3 (C4M5H3_ENTHI) Unreviewed, UniProtKB/TrEMBL

Last modified November 13, 2013. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA ligase RuleBase RU000617

EC=6.5.1.1 RuleBase RU000617
Gene names
ORF Names:EHI_111060 EMBL EAL52210.1
OrganismEntamoeba histolytica [Reference proteome]
Taxonomic identifier5759 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba

Protein attributes

Sequence length685 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617

Sequence similarities

Belongs to the ATP-dependent DNA ligase family.

Sequences

Sequence LengthMass (Da)Tools
C4M5H3 [UniParc].

Last modified July 7, 2009. Version 1.
Checksum: 594BA9A4207F93B7

FASTA68578,164
        10         20         30         40         50         60 
MSKRQSSLSR FFKPAKRATV GGQNNGENKS DEKGNEKKKQ ESIEEKNQSL QIKEEGNSFP 

        70         80         90        100        110        120 
EQKVKTLPFK GLADCFDALE NESGKLKKRE IYANYLKTVI TICPNDLTDV LNLTTGQIAP 

       130        140        150        160        170        180 
TWEGKELGIG DAILKDVVKS VTGLKLSQLN DKIKELGDIG IVAQNSKKNQ KLLVQPKPLT 

       190        200        210        220        230        240 
IQGVVLRMKE ILEADNSDIK KNKITALLVA AIGNEIRFIL RILKGVFRIG FTDRSLPPAI 

       250        260        270        280        290        300 
AQAVCSIRKE NNRIEELTEL ITNAVARVPS FQYLSEHITA NDPFEEFAKT NSVQLFIPFR 

       310        320        330        340        350        360 
PMLAKPKKSI TDITSRFKFP FTAEYKYDGE RGQIHFNKNK IMVFTRNLEN YTEKYPDVIE 

       370        380        390        400        410        420 
AVKDAVNPNI QSFIIDCEIV AFNRETNEFQ EFQILGRRAK KGVSVHSIAI NVCVNVFDIV 

       430        440        450        460        470        480 
YLNGKDLMDK PLKERRDILH STFHEVSQRF LFARFKNIEN EEDILPFFEE AINHRTEGLM 

       490        500        510        520        530        540 
CKTLIYDAEY IPDKRTDTWY KLKKDYLNGL ADTVDLVPVG AWMGEGKRAG VYGAFLLACR 

       550        560        570        580        590        600 
DEDSGDFETV TKVGTGFSDE ALQKLYEHLK TLECKEKKNV KHGDNLPDVW FEPKDVWEIK 

       610        620        630        640        650        660 
GADLSLSLQY KAGTKLVNTE GRGVCLRFPR YIRSRDDKEV NDITTNKQIY DLYKDQPSVR 

       670        680 
ETKDGQMKII NNDNEEESQE SEEKE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS571279 Genomic DNA. Translation: EAL52210.1.
RefSeqXP_657595.1. XM_652503.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING294381.C4M5H3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsrna_EHI_111060-1; rna_EHI_111060-1; EHI_111060.
GeneID3411902.
KEGGehi:EHI_111060.

Organism-specific databases

EuPathDBAmoebaDB:EHI_111060.

Phylogenomic databases

KOK10747.
ProtClustDBCLSZ2733228.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC4M5H3_ENTHI
AccessionPrimary (citable) accession number: C4M5H3
Entry history
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: November 13, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)