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C4M483

- C4M483_ENTHI

UniProt

C4M483 - C4M483_ENTHI

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Protein
Submitted name:

G protein alpha subunit, putative

Gene

EHI_140350

Organism
Entamoeba histolytica
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-KW
  3. signal transducer activity Source: InterPro

GO - Biological processi

  1. G-protein coupled receptor signaling pathway Source: InterPro
Complete GO annotation...

Keywords - Ligandi

GTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
G protein alpha subunit, putativeImported
Gene namesi
ORF Names:EHI_140350Imported
OrganismiEntamoeba histolyticaImported
Taxonomic identifieri5759 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba
ProteomesiUP000001926: Partially assembled WGS sequence

Organism-specific databases

EuPathDBiAmoebaDB:EHI_140350.

Interactioni

Protein-protein interaction databases

DIPiDIP-60100N.
STRINGi294381.C4M483.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4FIDX-ray2.62A/B22-358[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK04640.

Family and domain databases

Gene3Di1.10.400.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10218. PTHR10218. 1 hit.
PfamiPF00503. G-alpha. 1 hit.
[Graphical view]
PRINTSiPR00318. GPROTEINA.
SMARTiSM00275. G_alpha. 1 hit.
[Graphical view]
SUPFAMiSSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 2 hits.

Sequencei

Sequence statusi: Complete.

C4M483-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGCGQSKDNS IDKQIVEMAK SKPITVMLLG SGESGKSTIA KQLKILFGGG
60 70 80 90 100
FPEQERATHK SSICSNVVTC MRTLIEQSAI LNHPMKYQPK SKEFTTEDPV
110 120 130 140 150
TLPFSPELVG DVEALWADEG IQATYEESAK FQLPDCAKYL FENVKRIAME
160 170 180 190 200
DYVPTEEDLI HNRTKTTGIH EYDFVVKDIP FHLIDVGGQR SERKKWVSFF
210 220 230 240 250
SDVDCAIFVT SLAEYDMKLY EDGNTSRLTE SIAVFKDIMT NEFLKGAVKL
260 270 280 290 300
IFLNKMDLFE EKLTKVPLNT IFPEYTGGDN AVMGAQYIQQ LFTGKLQTEE
310 320 330 340 350
MNISGADGTA NIEGAVNEKV YTNPTNATDG SNIKRVFMLA VDVIMKNMAA

NGKMRPTK
Length:358
Mass (Da):39,947
Last modified:July 7, 2009 - v1
Checksum:i49A45E19F5364765
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK420232 mRNA. Translation: BAN38853.1.
AK421528 mRNA. Translation: BAN40068.1.
DS571254 Genomic DNA. Translation: EAL46350.2.
RefSeqiXP_651737.2. XM_646645.2.

Genome annotation databases

EnsemblProtistsirna_EHI_140350-1; rna_EHI_140350-1; EHI_140350.
GeneIDi3406047.
KEGGiehi:EHI_140350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK420232 mRNA. Translation: BAN38853.1 .
AK421528 mRNA. Translation: BAN40068.1 .
DS571254 Genomic DNA. Translation: EAL46350.2 .
RefSeqi XP_651737.2. XM_646645.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4FID X-ray 2.62 A/B 22-358 [» ]
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-60100N.
STRINGi 294381.C4M483.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi rna_EHI_140350-1 ; rna_EHI_140350-1 ; EHI_140350 .
GeneIDi 3406047.
KEGGi ehi:EHI_140350.

Organism-specific databases

EuPathDBi AmoebaDB:EHI_140350.

Phylogenomic databases

KOi K04640.

Family and domain databases

Gene3Di 1.10.400.10. 1 hit.
3.40.50.300. 2 hits.
InterProi IPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR10218. PTHR10218. 1 hit.
Pfami PF00503. G-alpha. 1 hit.
[Graphical view ]
PRINTSi PR00318. GPROTEINA.
SMARTi SM00275. G_alpha. 1 hit.
[Graphical view ]
SUPFAMi SSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 2 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 30459 / HM-1:IMSSImported.
  2. Lorenzi H., Amedeo P., Inman J., Schobel S., Caler E.
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: ATCC 30459 / HM-1:IMSSImported.
  3. "Heterotrimeric G-protein signaling is critical to pathogenic processes in Entamoeba histolytica."
    Bosch D.E., Kimple A.J., Muller R.E., Giguere P.M., Machius M., Willard F.S., Temple B.R., Siderovski D.P.
    PLoS Pathog. 8:e1003040-e1003040(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.62 ANGSTROMS) OF 22-358.
  4. "Short 5' UTR of Entamoeba genes."
    Hiranuka K., Kumagai M., Wakaguri H., Suzuki Y., Sugano S., Watanabe J., Makioka A.
    Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HM-1:IMSSImported.

Entry informationi

Entry nameiC4M483_ENTHI
AccessioniPrimary (citable) accession number: C4M483
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: November 26, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3