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C4LYV4

- C4LYV4_ENTHI

UniProt

C4LYV4 - C4LYV4_ENTHI

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Protein
Submitted name:

Putative uncharacterized protein

Gene
EHI_010670
Organism
Entamoeba histolytica
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. Rho guanyl-nucleotide exchange factor activity Source: InterPro

GO - Biological processi

  1. termination of G-protein coupled receptor signaling pathway Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
ORF Names:EHI_010670Imported
OrganismiEntamoeba histolytica
Taxonomic identifieri5759 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba
ProteomesiUP000001926: Partially assembled WGS sequence

Organism-specific databases

EuPathDBiAmoebaDB:EHI_010670.

Interactioni

Protein-protein interaction databases

DIPiDIP-60101N.
STRINGi294381.C4LYV4.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4GOUX-ray2.30A2-517[»]

Family & Domainsi

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
InterProiIPR000219. DH-domain.
IPR016137. Regulat_G_prot_signal_superfam.
IPR000342. RGS_dom.
[Graphical view]
PfamiPF00615. RGS. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF48097. SSF48097. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4LYV4-1 [UniParc]FASTAAdd to Basket

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MAATETAILE GWPTLQEVLE DSFMKRLLRC YLSDERSEEN LDFLESVGLY    50
ESQFDKLTPK VRLEALNFIK DQFLDRNSER QVNLSYQIQQ SILKKLSEVT 100
SNAPKDVFNE AKKATEYLLY TEQYTYFINK LNANTIGTGK KDVYSLYLNQ 150
FPKTNPQPLY KPTLNKIIEI EKKSWNEDEV KRNTESIKSL VESLIQDECN 200
YVGVLTSLSE FSEIMTKKQI LGPDVLKELF DHIPVLIQHH QKFISSLQEA 250
KADEKVGEKL NSGLHFLVLY RYYLRHVPKN IAKLCSIGMT DEIEVGRELY 300
PLPVIEEFDK QQKMTKKMSV LQMLVYPYFR VRTYQAYVDD FIKITKKDSQ 350
EVKELEVVHS QLAIFQELIN TYSDINKIER ISDALKLLFP FSFTSIMPLF 400
EGKNGICGIA SLDRFDKTDI NQLSMSLNSR KKLTLIILYR GVVVTDVPVI 450
RKKGNVSNSI DKSFYSFTLI GDIRDFGTED STETIYIDVP EIKKRIWFGC 500
ESTEEFKSCV EALRTILSN 519
Length:519
Mass (Da):60,137
Last modified:July 7, 2009 - v1
Checksum:i90DB6E8764F14109
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS571182 Genomic DNA. Translation: EAL47674.1.
RefSeqiXP_653063.1. XM_647971.1.

Genome annotation databases

EnsemblProtistsirna_EHI_010670-1; rna_EHI_010670-1; EHI_010670.
GeneIDi3407367.
KEGGiehi:EHI_010670.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS571182 Genomic DNA. Translation: EAL47674.1 .
RefSeqi XP_653063.1. XM_647971.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4GOU X-ray 2.30 A 2-517 [» ]
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-60101N.
STRINGi 294381.C4LYV4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi rna_EHI_010670-1 ; rna_EHI_010670-1 ; EHI_010670 .
GeneIDi 3407367.
KEGGi ehi:EHI_010670.

Organism-specific databases

EuPathDBi AmoebaDB:EHI_010670.

Family and domain databases

Gene3Di 1.20.900.10. 1 hit.
InterProi IPR000219. DH-domain.
IPR016137. Regulat_G_prot_signal_superfam.
IPR000342. RGS_dom.
[Graphical view ]
Pfami PF00615. RGS. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view ]
SUPFAMi SSF48065. SSF48065. 1 hit.
SSF48097. SSF48097. 1 hit.
PROSITEi PS50010. DH_2. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 30459 / HM-1:IMSS.
  2. Lorenzi H., Amedeo P., Inman J., Schobel S., Caler E.
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: ATCC 30459 / HM-1:IMSS.
  3. "Structural determinants of RGS-RhoGEF signaling critical to Entamoeba histolytica pathogenesis."
    Bosch D.E., Kimple A.J., Manning A.J., Muller R.E., Willard F.S., Machius M., Rogers S.L., Siderovski D.P.
    Structure 21:65-75(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 2-517.

Entry informationi

Entry nameiC4LYV4_ENTHI
AccessioniPrimary (citable) accession number: C4LYV4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: May 14, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

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