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Protein
Submitted name:

Uncharacterized protein

Gene

CL6EHI_010670

Organism
Entamoeba histolytica
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:CL6EHI_010670Imported, EHI_010670Imported
OrganismiEntamoeba histolyticaImported
Taxonomic identifieri5759 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba
Proteomesi
  • UP000001926 Componenti: Partially assembled WGS sequence
  • UP000078387 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiAmoebaDB:EHI_010670.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

DIPiDIP-60101N.
STRINGi5759.rna_EHI_010670-1.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4GOUX-ray2.30A2-517[»]
SMRiC4LYV4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 129RGSInterPro annotationAdd BLAST116
Domaini186 – 372DH (DBL-homology)InterPro annotationAdd BLAST187

Sequence similaritiesi

Contains 1 RGS domain.UniRule annotation

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
InterProiIPR000219. DH-domain.
IPR016137. RGS.
[Graphical view]
PfamiPF00615. RGS. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTiSM00315. RGS. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF48097. SSF48097. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4LYV4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATETAILE GWPTLQEVLE DSFMKRLLRC YLSDERSEEN LDFLESVGLY
60 70 80 90 100
ESQFDKLTPK VRLEALNFIK DQFLDRNSER QVNLSYQIQQ SILKKLSEVT
110 120 130 140 150
SNAPKDVFNE AKKATEYLLY TEQYTYFINK LNANTIGTGK KDVYSLYLNQ
160 170 180 190 200
FPKTNPQPLY KPTLNKIIEI EKKSWNEDEV KRNTESIKSL VESLIQDECN
210 220 230 240 250
YVGVLTSLSE FSEIMTKKQI LGPDVLKELF DHIPVLIQHH QKFISSLQEA
260 270 280 290 300
KADEKVGEKL NSGLHFLVLY RYYLRHVPKN IAKLCSIGMT DEIEVGRELY
310 320 330 340 350
PLPVIEEFDK QQKMTKKMSV LQMLVYPYFR VRTYQAYVDD FIKITKKDSQ
360 370 380 390 400
EVKELEVVHS QLAIFQELIN TYSDINKIER ISDALKLLFP FSFTSIMPLF
410 420 430 440 450
EGKNGICGIA SLDRFDKTDI NQLSMSLNSR KKLTLIILYR GVVVTDVPVI
460 470 480 490 500
RKKGNVSNSI DKSFYSFTLI GDIRDFGTED STETIYIDVP EIKKRIWFGC
510
ESTEEFKSCV EALRTILSN
Length:519
Mass (Da):60,137
Last modified:July 7, 2009 - v1
Checksum:i90DB6E8764F14109
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS571182 Genomic DNA. Translation: EAL47674.1.
BDEQ01000001 Genomic DNA. Translation: GAT94020.1.
RefSeqiXP_653063.1. XM_647971.1.

Genome annotation databases

EnsemblProtistsirna_EHI_010670-1; rna_EHI_010670-1; EHI_010670.
GeneIDi3407367.
KEGGiehi:EHI_010670.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS571182 Genomic DNA. Translation: EAL47674.1.
BDEQ01000001 Genomic DNA. Translation: GAT94020.1.
RefSeqiXP_653063.1. XM_647971.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4GOUX-ray2.30A2-517[»]
SMRiC4LYV4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60101N.
STRINGi5759.rna_EHI_010670-1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsirna_EHI_010670-1; rna_EHI_010670-1; EHI_010670.
GeneIDi3407367.
KEGGiehi:EHI_010670.

Organism-specific databases

EuPathDBiAmoebaDB:EHI_010670.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
InterProiIPR000219. DH-domain.
IPR016137. RGS.
[Graphical view]
PfamiPF00615. RGS. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTiSM00315. RGS. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF48097. SSF48097. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
PS50132. RGS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiC4LYV4_ENTHI
AccessioniPrimary (citable) accession number: C4LYV4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: November 30, 2016
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.