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Protein

Superoxide dismutase

Gene

EHI_159160

Organism
Entamoeba histolytica
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi27Divalent metal cationUniRule annotation1
Metal bindingi75Divalent metal cationUniRule annotation1
Metal bindingi156Divalent metal cationUniRule annotation1
Metal bindingi160Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
ORF Names:EHI_159160Imported
OrganismiEntamoeba histolyticaImported
Taxonomic identifieri5759 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba
Proteomesi
  • UP000001926 Componenti: Partially assembled WGS sequence

Organism-specific databases

EuPathDBiAmoebaDB:EHI_159160.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 82Sod_Fe_NInterPro annotationAdd BLAST81
Domaini89 – 188Sod_Fe_CInterPro annotationAdd BLAST100

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0876. Eukaryota.
COG0605. LUCA.
KOiK04564.
OMAiKWGSFDK.

Family and domain databases

InterProiView protein in InterPro
IPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
PfamiView protein in Pfam
PF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiView protein in PROSITE
PS00088. SOD_MN. 1 hit.

Sequencei

Sequence statusi: Complete.

C4LX20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFQLPQLPY AYNALEPHIS KETLEFHHDK HHATYVNKLN GLVKGTEQEH
60 70 80 90 100
KTLEELIKQK PTQAIYNNAA QAWNHAFYWK CMCGCGVKPS EQLIAKLTAA
110 120 130 140 150
FGGLEEFKKK FTEKAVGHFG SGWCWLVEHD GKLEIIDTHD AVNPMTNGMK
160 170 180 190
PLLTCDVWEH AYYIDTRNNR AAYLEHWWNV VNWKFVEEQL
Length:190
Mass (Da):22,060
Last modified:July 7, 2009 - v1
Checksum:i5C761B81C2F0539B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK420094 mRNA. Translation: BAN38722.1.
AK421104 mRNA. Translation: BAN39675.1.
AK421389 mRNA. Translation: BAN39945.1.
DS571167 Genomic DNA. Translation: EAL43440.1.
RefSeqiXP_648827.1. XM_643735.2.

Genome annotation databases

EnsemblProtistsiGAT93272; GAT93272; CL6EHI_159160.
rna_EHI_159160-1; rna_EHI_159160-1; EHI_159160.
GeneIDi3403104.
KEGGiehi:EHI_159160.

Similar proteinsi

Entry informationi

Entry nameiC4LX20_ENTHI
AccessioniPrimary (citable) accession number: C4LX20
Entry historyiIntegrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: September 27, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported