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Protein

Superoxide dismutase

Gene

EHI_159160

Organism
Entamoeba histolytica
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi27Divalent metal cationUniRule annotation1
Metal bindingi75Divalent metal cationUniRule annotation1
Metal bindingi156Divalent metal cationUniRule annotation1
Metal bindingi160Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
ORF Names:EHI_159160Imported
OrganismiEntamoeba histolyticaImported
Taxonomic identifieri5759 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba
Proteomesi
  • UP000001926 Componenti: Partially assembled WGS sequence

Organism-specific databases

EuPathDBiAmoebaDB:EHI_159160

Structurei

3D structure databases

SMRiC4LX20
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 82Sod_Fe_NInterPro annotationAdd BLAST81
Domaini89 – 188Sod_Fe_CInterPro annotationAdd BLAST100

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili36 – 56Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0876 Eukaryota
COG0605 LUCA
KOiK04564
OMAiKWGSFDK

Family and domain databases

Gene3Di1.10.287.990, 1 hit
2.40.500.20, 1 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

C4LX20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFQLPQLPY AYNALEPHIS KETLEFHHDK HHATYVNKLN GLVKGTEQEH
60 70 80 90 100
KTLEELIKQK PTQAIYNNAA QAWNHAFYWK CMCGCGVKPS EQLIAKLTAA
110 120 130 140 150
FGGLEEFKKK FTEKAVGHFG SGWCWLVEHD GKLEIIDTHD AVNPMTNGMK
160 170 180 190
PLLTCDVWEH AYYIDTRNNR AAYLEHWWNV VNWKFVEEQL
Length:190
Mass (Da):22,060
Last modified:July 7, 2009 - v1
Checksum:i5C761B81C2F0539B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK420094 mRNA Translation: BAN38722.1
AK421104 mRNA Translation: BAN39675.1
AK421389 mRNA Translation: BAN39945.1
DS571167 Genomic DNA Translation: EAL43440.1
RefSeqiXP_648827.1, XM_643735.2

Genome annotation databases

EnsemblProtistsiGAT93272; GAT93272; CL6EHI_159160
rna_EHI_159160-1; rna_EHI_159160-1; EHI_159160
GeneIDi3403104
KEGGiehi:EHI_159160

Similar proteinsi

Entry informationi

Entry nameiC4LX20_ENTHI
AccessioniPrimary (citable) accession number: C4LX20
Entry historyiIntegrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: March 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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