C4LX20 (C4LX20_ENTHI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Superoxide dismutase RuleBase RU000414
EC=1.15.1.1 RuleBase RU000414

Gene names

ORF Names:

EHI_159160 EMBL EAL43440.1

Organism

Entamoeba histolytica [Reference proteome]

Taxonomic identifier

5759 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Amoebozoa › Archamoebae › Entamoebidae › Entamoeba

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity. RuleBase RU000414
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2. RuleBase RU000414
Sequence similarities	Belongs to the iron/manganese superoxide dismutase family. RuleBase RU004477

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU000414 EMBL EAL43440.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: InterPro superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C4LX20 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: 5C761B81C2F0539B	FASTA	190	22,060
	10 20 30 40 50 60 MSFQLPQLPY AYNALEPHIS KETLEFHHDK HHATYVNKLN GLVKGTEQEH KTLEELIKQK 70 80 90 100 110 120 PTQAIYNNAA QAWNHAFYWK CMCGCGVKPS EQLIAKLTAA FGGLEEFKKK FTEKAVGHFG 130 140 150 160 170 180 SGWCWLVEHD GKLEIIDTHD AVNPMTNGMK PLLTCDVWEH AYYIDTRNNR AAYLEHWWNV 190 VNWKFVEEQL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome of the protist parasite Entamoeba histolytica." Loftus B.J., Anderson I., Davies R., Alsmark U.C., Samuelson J., Amedeo P., Roncaglia P., Berriman M., Hirt R.P., Mann B.J., Nozaki T., Suh B., Pop M., Duchene M., Ackers J., Tannich E., Leippe M., Hofer M. , Bruchhaus I., Willhoeft U., Bhattacharya A., Chillingworth T., Churcher C.M., Hance Z., Harris B., Harris D., Jagels K., Moule S., Mungall K.L., Ormond D., Squares R., Whitehead S., Quail M.A., Rabbinowitsch E., Norbertczak H., Price C., Wang Z., Guillen N., Gilchrist C., Stroup S.E., Bhattacharya S., Lohia A., Foster P.G., Sicheritz-Ponten T., Weber C., Singh U., Mukherjee C., El-Sayed N.M.A., Petri W.A., Clark C.G., Embley T.M., Barrell B.G., Fraser C.M., Hall N. Nature 433:865-868(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 30459 / HM-1:IMSS.
[2]	Lorenzi H., Amedeo P., Inman J., Schobel S., Caler E. Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 30459 / HM-1:IMSS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS571167 Genomic DNA. Translation: EAL43440.1.
RefSeq	XP_648827.1. XM_643735.2.
3D structure databases
ProteinModelPortal	C4LX20.
SMR	C4LX20. Positions 2-190.
ModBase	Search...
Protein-protein interaction databases
STRING	294381.C4LX20.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	rna_EHI_159160-1; rna_EHI_159160-1; EHI_159160.
GeneID	3403104.
KEGG	ehi:EHI_159160.
Organism-specific databases
EuPathDB	AmoebaDB:EHI_159160.
Phylogenomic databases
KO	K04564.
ProtClustDB	CLSZ2729648.
Family and domain databases
InterPro	IPR001189. Mn/Fe_SOD. IPR019833. Mn/Fe_SOD_BS. IPR019832. Mn/Fe_SOD_C. IPR019831. Mn/Fe_SOD_N. [Graphical view]
PANTHER	PTHR11404. PTHR11404. 1 hit.
Pfam	PF02777. Sod_Fe_C. 1 hit. PF00081. Sod_Fe_N. 1 hit. [Graphical view]
PIRSF	PIRSF000349. SODismutase. 1 hit.
PRINTS	PR01703. MNSODISMTASE.
SUPFAM	SSF46609. SODismutase. 1 hit. SSF54719. SODismutase. 1 hit.
PROSITE	PS00088. SOD_MN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C4LX20_ENTHI

Accession

Primary (citable) accession number: C4LX20

Entry history

Integrated into UniProtKB/TrEMBL:	July 7, 2009
Last sequence update:	July 7, 2009
Last modified:	April 3, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)