C4LKW4 (C4LKW4_CORK4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase HAMAP MF_01554
EC=5.4.2.10 HAMAP MF_01554

Gene names

Name:	pmmC EMBL ACR18469.1
Synonyms:	glmM HAMAP MF_01554
Ordered Locus Names:	ckrop_1748

Organism

Corynebacterium kroppenstedtii (strain DSM 44385 / CCUG 35717) [Complete proteome] [HAMAP]

Taxonomic identifier

645127 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554
Sequence similarities	Belongs to the phosphohexose mutase family. HAMAP MF_01554

Ontologies

Keywords
Ligand	Magnesium HAMAP MF_01554 Metal-binding HAMAP MF_01554
Molecular function	Isomerase HAMAP MF_01554 EMBL ACR18469.1
PTM	Phosphoprotein HAMAP MF_01554
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	104	1	Phosphoserine intermediate By similarity HAMAP MF_01554
	Metal binding	104	1	Magnesium; via phosphate group By similarity HAMAP MF_01554
	Metal binding	243	1	Magnesium By similarity HAMAP MF_01554
	Metal binding	245	1	Magnesium By similarity HAMAP MF_01554
	Metal binding	247	1	Magnesium By similarity HAMAP MF_01554
Amino acid modifications
	Modified residue	104	1	Phosphoserine By similarity HAMAP MF_01554

Sequences

	Sequence		Length	Mass (Da)
	C4LKW4 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: B0C024E36FBA1D30	FASTA	447	46,315
	10 20 30 40 50 60 MGRRYFGTDG VRGLANKTLT APLAMKLGSA AAKVLTANRK GGRRPVAVVG RDPRVSGEML 70 80 90 100 110 120 SAALSAGMAS QGVDVLRVGV IPTPAVAFLT DDYGADMGVV ISASHNPMPD NGIKFFAAGG 130 140 150 160 170 180 LKLDDAVEAE IEATMLELSE TGPTGAGIGR IVEESPDALE RYLFHLAGAV PTPLDGIRVV 190 200 210 220 230 240 VDCANGAAST AAPMAYQAAG ADVVPIFNKP NAFNINENCG STHIDVLQRA VLEHHADLGL 250 260 270 280 290 300 AHDGDADRCL AVDSEGNVVD GDQIMAILAI AMKEGGELKK STLVATVMSN LGLKLAMKEQ 310 320 330 340 350 360 GIEVRTTKVG DRYVLADLNA GDYSLGGEQS GHIVIPEHGT TGDGTLTGLS VMVRMAQTGK 370 380 390 400 410 420 TLSELASVMR VLPQTLINVP VTDKAAITND EAVRTAITEA EEELGESGRV LLRPSGTEEL 430 440 FRVMVEAGDG ATARKIAGRL AAVVASV

References

[1]

"Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids." Tauch A., Schneider J., Szczepanowski R., Tilker A., Viehoever P., Gartemann K.-H., Arnold W., Blom J., Brinkrolf K., Brune I., Goetker S., Weisshaar B., Goesmann A., Droege M., Puehler A. J. Biotechnol. 136:22-30(2008) [PubMed: 18430482] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44385 / CCUG 35717.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001620 Genomic DNA. Translation: ACR18469.1.
RefSeq	YP_002907012.1. NC_012704.1.
3D structure databases
ProteinModelPortal	C4LKW4.
ModBase	Search...
Protein-protein interaction databases
STRING	C4LKW4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7876108.
GenomeReviews	Gene locus ckrop_1748 in contig CP001620_GR.
KEGG	ckp:ckrop_1748.
PATRIC	21518905. VBICorKro120627_1806.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GVGSTHL.
ProtClustDB	PRK14318.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C4LKW4_CORK4

Accession

Primary (citable) accession number: C4LKW4

Entry history

Integrated into UniProtKB/TrEMBL:	July 7, 2009
Last sequence update:	July 7, 2009
Last modified:	January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)