C4LJY7 (MURI_CORK4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	ckrop_1402

Organism

Corynebacterium kroppenstedtii (strain DSM 44385 / CCUG 35717) [Complete proteome] [HAMAP]

Taxonomic identifier

645127 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	288 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 288	288	Glutamate racemase HAMAP MF_00258		PRO_1000204625

Sequences

	Sequence		Length	Mass (Da)
	C4LJY7 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: 56D84085BA6464FA	FASTA	288	30,842
	10 20 30 40 50 60 MKNSPIGVFD SGVGGLTVAR TIVDQAPTES IMYVGDTAHA PYGPKPREDI IRYSTAIADD 70 80 90 100 110 120 LVARGAKMIV IACNTAASVF LDKARELYDV PVVGVIEPAS RRAVAATRNG RVGVIGTTGT 130 140 150 160 170 180 IASGAYQRCI ANLDPNIEVH AVDCPQFVPF VERGITTGRQ IMGLAEAYLE PLQDVGVDTV 190 200 210 220 230 240 VLGCTHYPLL TGVIQLVMGD NVTLVSSSEE EGKEVPRVLY QEDLFNDANP EAESLDVVDA 250 260 270 280 NVVNDYAGPE PVRTFESTGD PHRFARLARR FLGPSITQVS HVEGLTDM

References

[1]

"Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids." Tauch A., Schneider J., Szczepanowski R., Tilker A., Viehoever P., Gartemann K.-H., Arnold W., Blom J., Brinkrolf K., Brune I., Goetker S., Weisshaar B., Goesmann A., Droege M., Puehler A. J. Biotechnol. 136:22-30(2008) [PubMed: 18430482] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44385 / CCUG 35717.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001620 Genomic DNA. Translation: ACR18142.1.
RefSeq	YP_002906685.1. NC_012704.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C4LJY7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7877209.
GenomeReviews	Gene locus ckrop_1402 in contig CP001620_GR.
KEGG	ckp:ckrop_1402.
PATRIC	21518171. VBICorKro120627_1441.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	PQEDTIY.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. False negative. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_CORK4

Accession

Primary (citable) accession number: C4LJY7

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	July 7, 2009
Last modified:	January 25, 2012
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program