C4LJN2 (C4LJN2_CORK4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase HAMAP MF_00123
EC=6.1.1.19 HAMAP MF_00123

Alternative name(s):
Arginyl-tRNA synthetase HAMAP MF_00123

Gene names

Name:	argS HAMAP MF_00123
Ordered Locus Names:	ckrop_1292

Organism

Corynebacterium kroppenstedtii (strain DSM 44385 / CCUG 35717) [Complete proteome] [HAMAP]

Taxonomic identifier

645127 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	594 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity. HAMAP MF_00123
Subcellular location	Cytoplasm By similarity HAMAP MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP MF_00123

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP MF_00123
Cellular component	Cytoplasm HAMAP MF_00123
Ligand	ATP-binding HAMAP MF_00123 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase HAMAP MF_00123 EMBL ACR18037.1 Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Motif	170 – 180	11	"HIGH" region By similarity HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	C4LJN2 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: 3826535A7BEA2045	FASTA	594	65,014
	10 20 30 40 50 60 MSWHQRSALT NGSINRNRQR AGTALGSDRE PRRGAVHCGP MTPEELSTLI ATRAESVLSH 70 80 90 100 110 120 HGKDASVLPL TVTVERPRNP EHGDYATNLA LQIAKKVGTS PRELAGWLAE DLATNSAIET 130 140 150 160 170 180 VDVAGPGFLN IRLAAAAQGE IVGRILAEGE RFGSSSELSD EVINLEFVSA NPTGPIHLGG 190 200 210 220 230 240 TRWAAVGDAL GRIFAFRGAS ITREYYFNDH GRQIDRFARS LVAAALGQPT PEDGYGGEYI 250 260 270 280 290 300 QDIASSVVDK HPEATQLPLE ERQELFRKEG VDLMFAHIKR TLHEFGTDFD VFFHENSLFE 310 320 330 340 350 360 SGAVDQAIQK LKDNGNLYEA DGAWWLRSTS FGDDKDRVVI KSDGDAAYIA GDIAYIRDKI 370 380 390 400 410 420 ERGHNLCIYM LGADHHGYIA RLKAAAQALG YDPTQVEVLI GQMVNLVRDG KAVKMSKRAG 430 440 450 460 470 480 TVITLDDLVE LIGVDAARYA LIRSSVDQTL DIDMDLWARQ TNDNPVFYVQ YAHARLCSLG 490 500 510 520 530 540 RKAQAAGILV KDPDYSLLVN DYEGALIRTL GEFPSVVGTA AELREPHRIA RYMEELAGTF 550 560 570 580 590 HRFYDSCQIL PKKSEPTGDE AAPIVHARLA LAQATRQTIA NALSLLGVSA PERM

References

[1]

"Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids." Tauch A., Schneider J., Szczepanowski R., Tilker A., Viehoever P., Gartemann K.-H., Arnold W., Blom J., Brinkrolf K., Brune I., Goetker S., Weisshaar B., Goesmann A., Droege M., Puehler A. J. Biotechnol. 136:22-30(2008) [PubMed: 18430482] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44385 / CCUG 35717.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001620 Genomic DNA. Translation: ACR18037.1.
RefSeq	YP_002906580.1. NC_012704.1.
3D structure databases
ProteinModelPortal	C4LJN2.
ModBase	Search...
Protein-protein interaction databases
STRING	C4LJN2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7875581.
GenomeReviews	Gene locus ckrop_1292 in contig CP001620_GR.
KEGG	ckp:ckrop_1292.
PATRIC	21517933. VBICorKro120627_1329.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	FDVYFHE.
ProtClustDB	PRK01611.
Family and domain databases
HAMAP	MF_00123. Arg_tRNA_synth. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KO	K01887.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF55190. Arg-tRNA-synth_Ic_N. 1 hit. SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMs	TIGR00456. ArgS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C4LJN2_CORK4

Accession

Primary (citable) accession number: C4LJN2

Entry history

Integrated into UniProtKB/TrEMBL:	July 7, 2009
Last sequence update:	July 7, 2009
Last modified:	January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)