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Protein

Sec-independent protein translocase protein TatC

Gene

tatC

Organism
Corynebacterium kroppenstedtii (strain DSM 44385 / JCM 11950 / CIP 105744 / CCUG 35717)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciCKRO645127:GI7D-897-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatCUniRule annotation
Gene namesi
Name:tatCUniRule annotation
Ordered Locus Names:ckrop_0907
OrganismiCorynebacterium kroppenstedtii (strain DSM 44385 / JCM 11950 / CIP 105744 / CCUG 35717)
Taxonomic identifieri645127 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000001473 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei45 – 6521HelicalUniRule annotationAdd
BLAST
Transmembranei119 – 13921HelicalUniRule annotationAdd
BLAST
Transmembranei157 – 17721HelicalUniRule annotationAdd
BLAST
Transmembranei200 – 22021HelicalUniRule annotationAdd
BLAST
Transmembranei238 – 25821HelicalUniRule annotationAdd
BLAST
Transmembranei259 – 27921HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 414414Sec-independent protein translocase protein TatCPRO_0000412861Add
BLAST

Interactioni

Subunit structurei

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.UniRule annotation

Protein-protein interaction databases

STRINGi645127.ckrop_0907.

Family & Domainsi

Sequence similaritiesi

Belongs to the TatC family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DCX. Bacteria.
COG0805. LUCA.
HOGENOMiHOG000245380.
KOiK03118.
OMAiNDIIMAP.
OrthoDBiPOG091H02DA.

Family and domain databases

HAMAPiMF_00902. TatC. 1 hit.
InterProiIPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view]
PANTHERiPTHR30371:SF0. PTHR30371:SF0. 2 hits.
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.
PROSITEiPS01218. TATC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4LIK6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQSTSVSKG GRVSRKAKKN PDGTMSIVDH LRELRTRLLR ALAAIAVTTI
60 70 80 90 100
IGFIWYEHGI PAWAIGPLHV PRLPSLGEIL KEPYCSLPPS ARATFSADNE
110 120 130 140 150
CRLLATSPFE MFMLRMKMGG LAGLVMACPI WLIEIWRFIT PGLLKNERRW
160 170 180 190 200
TLSVGTIAGF LFVLGVVAAY LVLPMGLDVL LHLGDSTQIS ALTGEKYFNF
210 220 230 240 250
VIALILVFGL SFEVPLFTAM LNLAGVVHYE QLKDKRRIMI VVIFIFAAIA
260 270 280 290 300
TPGQDPISML VLALTLVVLM ELALQFTRIH DRRAARHVSE WEGLSDDEAS
310 320 330 340 350
PLKVAPSSIP AAESIYDGDH KGIAGGGDAH PAGGSGPIPK PSPVTAPTRA
360 370 380 390 400
PSASESPTPT PSPAPSDSPT SGSHHAPPAA VLRRGPRSWN DSTGDNDGKP
410
GQDTIQSSSF DDVL
Length:414
Mass (Da):44,492
Last modified:July 7, 2009 - v1
Checksum:i72CA6C427CE0409E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001620 Genomic DNA. Translation: ACR17661.1.
RefSeqiWP_012731548.1. NC_012704.1.

Genome annotation databases

EnsemblBacteriaiACR17661; ACR17661; ckrop_0907.
KEGGickp:ckrop_0907.
PATRICi21517129. VBICorKro120627_0935.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001620 Genomic DNA. Translation: ACR17661.1.
RefSeqiWP_012731548.1. NC_012704.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi645127.ckrop_0907.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACR17661; ACR17661; ckrop_0907.
KEGGickp:ckrop_0907.
PATRICi21517129. VBICorKro120627_0935.

Phylogenomic databases

eggNOGiENOG4105DCX. Bacteria.
COG0805. LUCA.
HOGENOMiHOG000245380.
KOiK03118.
OMAiNDIIMAP.
OrthoDBiPOG091H02DA.

Enzyme and pathway databases

BioCyciCKRO645127:GI7D-897-MONOMER.

Family and domain databases

HAMAPiMF_00902. TatC. 1 hit.
InterProiIPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view]
PANTHERiPTHR30371:SF0. PTHR30371:SF0. 2 hits.
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.
PROSITEiPS01218. TATC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTATC_CORK4
AccessioniPrimary (citable) accession number: C4LIK6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: July 7, 2009
Last modified: September 7, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.