C4LGU9 (DCD_CORK4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	ckrop_0268

Organism

Corynebacterium kroppenstedtii (strain DSM 44385 / CCUG 35717) [Complete proteome] [HAMAP]

Taxonomic identifier

645127 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium › Corynebacterium kroppenstedtii

Protein attributes

Sequence length	187 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 187	187	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000203356

Sequences

	Sequence		Length	Mass (Da)
	C4LGU9 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: 6B368DD1A79C5160	FASTA	187	20,468
	10 20 30 40 50 60 MILSDRDIRS AIDSGHLGIS PFDPTMVQPS SIDVRLDRYF RVFNNARYTH IDPKQEQEDL 70 80 90 100 110 120 TSLVEVKEGD AFILHPGEFV LGSTLEEFAL PADLAGRLEG KSSLGRLGLL THSTAGFIDP 130 140 150 160 170 180 GFNGYITFEL SNASNLPIAL YPEMKVGQLA LFMMSSPAET PYGSGSLGSK YQGQRGPTAS KAYMNFR

References

[1]

"Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385 revealed insights into the physiology of a lipophilic corynebacterium that lacks mycolic acids." Tauch A., Schneider J., Szczepanowski R., Tilker A., Viehoever P., Gartemann K.-H., Arnold W., Blom J., Brinkrolf K., Brune I., Goetker S., Weisshaar B., Goesmann A., Droege M., Puehler A. J. Biotechnol. 136:22-30(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 44385 / CCUG 35717.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001620 Genomic DNA. Translation: ACR17054.1.
RefSeq	YP_002905597.1. NC_012704.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	645127.ckrop_0268.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACR17054; ACR17054; ckrop_0268.
GeneID	7875458.
KEGG	ckp:ckrop_0268.
PATRIC	21515773. VBICorKro120627_0277.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	RSVLTVC.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	CKRO645127:GI7D-269-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CORK4

Accession

Primary (citable) accession number: C4LGU9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	July 7, 2009
Last modified:	May 29, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program