C4LEX2 (DCD_TOLAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Tola_1528

Organism

Tolumonas auensis (strain DSM 9187 / TA4) [Complete proteome] [HAMAP]

Taxonomic identifier

595494 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Tolumonas › Tolumonas auensis

Protein attributes

Sequence length	193 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 193	193	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000203370

Sequences

	Sequence		Length	Mass (Da)
	C4LEX2 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: B4566330B5F2610E	FASTA	193	21,293
	10 20 30 40 50 60 MRLCDRDIEQ HLEEGKIVIE PRPDSSRISG VSVDVLLGNE FRVFQAHTAP YIDLSGPKEE 70 80 90 100 110 120 VSAAIDRVMS DEIYIKDSEV FILHPGELAL AVTHESVTLP DNIVGWLDGR SSLARLGLMV 130 140 150 160 170 180 HVTAHRIDPG WSGRIVLEFY NGGRLPLALR PGMVIGALNF ETMSGSAARP YNKRTNAKYK 190 SQQGAVASRI DQD

References

[1]

"Complete sequence of Tolumonas auensis DSM 9187." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Spring S., Beller H. Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 9187 / TA4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001616 Genomic DNA. Translation: ACQ93139.1.
RefSeq	YP_002892725.1. NC_012691.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	595494.Tola_1528.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACQ93139; ACQ93139; Tola_1528.
GeneID	7885129.
KEGG	tau:Tola_1528.
PATRIC	23979687. VBITolAue42623_1520.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	TAUE595494:GHEF-1579-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_TOLAT

Accession

Primary (citable) accession number: C4LEX2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	July 7, 2009
Last modified:	May 29, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program