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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Tolumonas auensis (strain DSM 9187 / TA4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:Tola_1513
OrganismiTolumonas auensis (strain DSM 9187 / TA4)
Taxonomic identifieri595494 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeTolumonas
Proteomesi
  • UP000009073 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002042041 – 497Probable malate:quinone oxidoreductaseAdd BLAST497

Interactioni

Protein-protein interaction databases

STRINGi595494.Tola_1513

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiPQHDMAL
OrthoDBiPOG091H0B7C

Family and domain databases

Gene3Di3.50.50.60, 2 hits
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

C4LEV7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASIHADVTL VGGGIMSATL AMLIHRLDPA LHICMIEQLP DIALESSGAL
60 70 80 90 100
NNAGTGHAGY CELNYTPHDK DGNVLIQRAL EINAAFEVSL QFWSHLVNAD
110 120 130 140 150
RENITPSSFI NRVPHLSAVW GQKDIDFLKA RYTLLKSHHL FSEMKWSEDE
160 170 180 190 200
QTLADWMPLM MKGRQAEPKL AATRVEHGAD VNFGALTRIL VSYLQKNANF
210 220 230 240 250
ELLTNTRVVD LHRAHGAKKP WAVKVKNQNS AAKQTIESPF VFLGAGGVAL
260 270 280 290 300
HLLQNSGIEE AAGYGGFPVS GQWLICQNQD LIRQHHAKVY SLAAVGAPPM
310 320 330 340 350
SVPHLDTRII NGKPSLLFGP YAGFTTKFLK HGSPFDLAKS VRPHNLKSLI
360 370 380 390 400
GAGKNNFDLT KYLVKEVFQT HSQRMQSLEA FIPNARAEDW QLAHAGKRVQ
410 420 430 440 450
IIKRCHHKWG KLEFGTEIVA AEDGSLAALL GASPGASVSV KTMLDVLERC
460 470 480 490
FPQQMQSAEW QDKLKTMIPS YGRSLINDAN LSASVRRYTL DTLKLSS
Length:497
Mass (Da):54,804
Last modified:July 7, 2009 - v1
Checksum:i25240F9F6BDFD8D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001616 Genomic DNA Translation: ACQ93124.1
RefSeqiWP_015878596.1, NC_012691.1

Genome annotation databases

EnsemblBacteriaiACQ93124; ACQ93124; Tola_1513
KEGGitau:Tola_1513

Similar proteinsi

Entry informationi

Entry nameiMQO_TOLAT
AccessioniPrimary (citable) accession number: C4LEV7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 7, 2009
Last modified: February 28, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health