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C4LAA1

- TYPH_TOLAT

UniProt

C4LAA1 - TYPH_TOLAT

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Protein

Putative thymidine phosphorylase

Gene
Tola_2482
Organism
Tolumonas auensis (strain DSM 9187 / TA4)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. phosphorylase activity Source: InterPro
  2. thymidine phosphorylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pyrimidine nucleobase metabolic process Source: InterPro
  2. pyrimidine nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciTAUE595494:GHEF-2560-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylase (EC:2.4.2.4)
Alternative name(s):
TdRPase
Gene namesi
Ordered Locus Names:Tola_2482
OrganismiTolumonas auensis (strain DSM 9187 / TA4)
Taxonomic identifieri595494 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeTolumonas
ProteomesiUP000009073: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 505505Putative thymidine phosphorylaseUniRule annotationPRO_1000212645Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi595494.Tola_2482.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiFICISEG.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4LAA1-1 [UniParc]FASTAAdd to Basket

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MSARITPQTP ALQALRMRLH AQHQPVVLMR TDCHVCRAEG LAPRSQVLII    50
AGDRTVQALL YQIDSDLLKT GQIALSEAAW DALDIHEGDL VQVRHPPLLE 100
SLSAVRARIH GHRLQTTELQ AIVRDVVDGR YTDVALSAFL TATAVLPLDM 150
QETIHLTRAM VDVGDHLQWQ APIVVDKHCV GGLPGNRTTP LVVAIAAANG 200
LVMPKTSSRA ITSPAGTADT METLAPVDLD LDTLRKVVEK EGGCVAWGGA 250
MHLSPADDIF VRIERELDID TQGQLIASVL SKKIAAGATH IVIDIPVGPT 300
AKVRSRETAE HLAHHLSEVA ASFGLVLRCL FTDGNQPVGR GIGPALEARD 350
VLAVLRNEAD APQDLCDRVA LVAGAVLELG GVAKEGDGIR LAHETISSGR 400
AWEKFQRICA AQGGFREPPQ ALYVEPLLAT TTGRAVHIDN RKLSRLAKLA 450
GAPESSAAGI QLQVRLGDEV TSGQPLMFLH AQTSGEMAYA LAYVHDIGDI 500
VNIEP 505
Length:505
Mass (Da):54,040
Last modified:July 7, 2009 - v1
Checksum:i5FE1A9E834782093
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001616 Genomic DNA. Translation: ACQ94076.1.
RefSeqiYP_002893662.1. NC_012691.1.

Genome annotation databases

EnsemblBacteriaiACQ94076; ACQ94076; Tola_2482.
GeneIDi7885204.
KEGGitau:Tola_2482.
PATRICi23981627. VBITolAue42623_2465.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001616 Genomic DNA. Translation: ACQ94076.1 .
RefSeqi YP_002893662.1. NC_012691.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 595494.Tola_2482.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACQ94076 ; ACQ94076 ; Tola_2482 .
GeneIDi 7885204.
KEGGi tau:Tola_2482.
PATRICi 23981627. VBITolAue42623_2465.

Phylogenomic databases

eggNOGi COG0213.
HOGENOMi HOG000252767.
KOi K00758.
OMAi FICISEG.
OrthoDBi EOG61ZTGG.

Enzyme and pathway databases

BioCyci TAUE595494:GHEF-2560-MONOMER.

Family and domain databases

Gene3Di 3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPi MF_00703. Thymid_phosp_2.
InterProi IPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view ]
PANTHERi PTHR10515. PTHR10515. 1 hit.
Pfami PF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF000478. TP_PyNP. 1 hit.
SMARTi SM00941. PYNP_C. 1 hit.
[Graphical view ]
SUPFAMi SSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsi TIGR02645. ARCH_P_rylase. 1 hit.
PROSITEi PS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 9187 / TA4.

Entry informationi

Entry nameiTYPH_TOLAT
AccessioniPrimary (citable) accession number: C4LAA1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 7, 2009
Last modified: May 14, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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