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Protein

Putative thymidine phosphorylase

Gene

Tola_2482

Organism
Tolumonas auensis (strain DSM 9187 / TA4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciTAUE595494:GHEF-2523-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPaseUniRule annotation
Gene namesi
Ordered Locus Names:Tola_2482
OrganismiTolumonas auensis (strain DSM 9187 / TA4)
Taxonomic identifieri595494 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeTolumonas
Proteomesi
  • UP000009073 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002126451 – 505Putative thymidine phosphorylaseAdd BLAST505

Interactioni

Protein-protein interaction databases

STRINGi595494.Tola_2482

Structurei

3D structure databases

SMRiC4LAA1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMW Bacteria
COG0213 LUCA
HOGENOMiHOG000252767
KOiK00758
OMAiANEIYEC
OrthoDBiPOG091H02BC

Family and domain databases

Gene3Di3.40.1030.10, 1 hit
3.90.1170.30, 1 hit
HAMAPiMF_00703 Thymid_phosp_2, 1 hit
InterProiView protein in InterPro
IPR000312 Glycosyl_Trfase_fam3
IPR017459 Glycosyl_Trfase_fam3_N_dom
IPR036320 Glycosyl_Trfase_fam3_N_dom)sf
IPR035902 Nuc_phospho_transferase
IPR036566 PYNP-like_C_sf
IPR013102 PYNP_C
IPR017872 Pyrmidine_PPase_CS
IPR028579 Thym_Pase_Put
IPR013466 Thymidine/AMP_Pase
IPR000053 Thymidine/pyrmidine_PPase
PANTHERiPTHR10515 PTHR10515, 1 hit
PfamiView protein in Pfam
PF02885 Glycos_trans_3N, 1 hit
PF00591 Glycos_transf_3, 1 hit
PF07831 PYNP_C, 1 hit
PIRSFiPIRSF000478 TP_PyNP, 1 hit
SMARTiView protein in SMART
SM00941 PYNP_C, 1 hit
SUPFAMiSSF47648 SSF47648, 1 hit
SSF52418 SSF52418, 1 hit
SSF54680 SSF54680, 1 hit
TIGRFAMsiTIGR02645 ARCH_P_rylase, 1 hit
PROSITEiView protein in PROSITE
PS00647 THYMID_PHOSPHORYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

C4LAA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSARITPQTP ALQALRMRLH AQHQPVVLMR TDCHVCRAEG LAPRSQVLII
60 70 80 90 100
AGDRTVQALL YQIDSDLLKT GQIALSEAAW DALDIHEGDL VQVRHPPLLE
110 120 130 140 150
SLSAVRARIH GHRLQTTELQ AIVRDVVDGR YTDVALSAFL TATAVLPLDM
160 170 180 190 200
QETIHLTRAM VDVGDHLQWQ APIVVDKHCV GGLPGNRTTP LVVAIAAANG
210 220 230 240 250
LVMPKTSSRA ITSPAGTADT METLAPVDLD LDTLRKVVEK EGGCVAWGGA
260 270 280 290 300
MHLSPADDIF VRIERELDID TQGQLIASVL SKKIAAGATH IVIDIPVGPT
310 320 330 340 350
AKVRSRETAE HLAHHLSEVA ASFGLVLRCL FTDGNQPVGR GIGPALEARD
360 370 380 390 400
VLAVLRNEAD APQDLCDRVA LVAGAVLELG GVAKEGDGIR LAHETISSGR
410 420 430 440 450
AWEKFQRICA AQGGFREPPQ ALYVEPLLAT TTGRAVHIDN RKLSRLAKLA
460 470 480 490 500
GAPESSAAGI QLQVRLGDEV TSGQPLMFLH AQTSGEMAYA LAYVHDIGDI

VNIEP
Length:505
Mass (Da):54,040
Last modified:July 7, 2009 - v1
Checksum:i5FE1A9E834782093
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001616 Genomic DNA Translation: ACQ94076.1
RefSeqiWP_015879528.1, NC_012691.1

Genome annotation databases

EnsemblBacteriaiACQ94076; ACQ94076; Tola_2482
KEGGitau:Tola_2482

Similar proteinsi

Entry informationi

Entry nameiTYPH_TOLAT
AccessioniPrimary (citable) accession number: C4LAA1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 7, 2009
Last modified: March 28, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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