Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

C4LAA1 (TYPH_TOLAT) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative thymidine phosphorylase

EC=2.4.2.4
Alternative name(s):
TdRPase
Gene names
Ordered Locus Names:Tola_2482
OrganismTolumonas auensis (strain DSM 9187 / TA4) [Complete proteome] [HAMAP]
Taxonomic identifier595494 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeTolumonas

Protein attributes

Sequence length505 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_00703

Sequence similarities

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 505505Putative thymidine phosphorylase HAMAP-Rule MF_00703
PRO_1000212645

Sequences

Sequence LengthMass (Da)Tools
C4LAA1 [UniParc].

Last modified July 7, 2009. Version 1.
Checksum: 5FE1A9E834782093

FASTA50554,040
        10         20         30         40         50         60 
MSARITPQTP ALQALRMRLH AQHQPVVLMR TDCHVCRAEG LAPRSQVLII AGDRTVQALL 

        70         80         90        100        110        120 
YQIDSDLLKT GQIALSEAAW DALDIHEGDL VQVRHPPLLE SLSAVRARIH GHRLQTTELQ 

       130        140        150        160        170        180 
AIVRDVVDGR YTDVALSAFL TATAVLPLDM QETIHLTRAM VDVGDHLQWQ APIVVDKHCV 

       190        200        210        220        230        240 
GGLPGNRTTP LVVAIAAANG LVMPKTSSRA ITSPAGTADT METLAPVDLD LDTLRKVVEK 

       250        260        270        280        290        300 
EGGCVAWGGA MHLSPADDIF VRIERELDID TQGQLIASVL SKKIAAGATH IVIDIPVGPT 

       310        320        330        340        350        360 
AKVRSRETAE HLAHHLSEVA ASFGLVLRCL FTDGNQPVGR GIGPALEARD VLAVLRNEAD 

       370        380        390        400        410        420 
APQDLCDRVA LVAGAVLELG GVAKEGDGIR LAHETISSGR AWEKFQRICA AQGGFREPPQ 

       430        440        450        460        470        480 
ALYVEPLLAT TTGRAVHIDN RKLSRLAKLA GAPESSAAGI QLQVRLGDEV TSGQPLMFLH 

       490        500 
AQTSGEMAYA LAYVHDIGDI VNIEP 

« Hide

References

[1]"Complete sequence of Tolumonas auensis DSM 9187."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Spring S., Beller H.
Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 9187 / TA4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001616 Genomic DNA. Translation: ACQ94076.1.
RefSeqYP_002893662.1. NC_012691.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING595494.Tola_2482.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACQ94076; ACQ94076; Tola_2482.
GeneID7885204.
KEGGtau:Tola_2482.
PATRIC23981627. VBITolAue42623_2465.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0213.
HOGENOMHOG000252767.
KOK00758.
OMACHSEGFE.
OrthoDBEOG61ZTGG.
ProtClustDBPRK04350.

Enzyme and pathway databases

BioCycTAUE595494:GHEF-2560-MONOMER.

Family and domain databases

Gene3D3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPMF_00703. Thymid_phosp_2.
InterProIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERPTHR10515. PTHR10515. 1 hit.
PfamPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFPIRSF000478. TP_PyNP. 1 hit.
SMARTSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTYPH_TOLAT
AccessionPrimary (citable) accession number: C4LAA1
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 7, 2009
Last modified: February 19, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families