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C4L9L6

- APAH_TOLAT

UniProt

C4L9L6 - APAH_TOLAT

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Protein
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical
Gene
apaH, Tola_2372
Organism
Tolumonas auensis (strain DSM 9187 / TA4)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP By similarity.UniRule annotation

Catalytic activityi

P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

  1. bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciTAUE595494:GHEF-2449-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC:3.6.1.41)
Alternative name(s):
Ap4A hydrolase
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase
Diadenosine tetraphosphatase
Gene namesi
Name:apaH
Ordered Locus Names:Tola_2372
OrganismiTolumonas auensis (strain DSM 9187 / TA4)
Taxonomic identifieri595494 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeTolumonas
ProteomesiUP000009073: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 276276Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation
PRO_1000204090Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi595494.Tola_2372.

Structurei

3D structure databases

ProteinModelPortaliC4L9L6.

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.

Phylogenomic databases

eggNOGiCOG0639.
HOGENOMiHOG000251871.
KOiK01525.
OMAiINAFTRM.
OrthoDBiEOG66B3WP.

Family and domain databases

Gene3Di3.60.21.10. 2 hits.
HAMAPiMF_00199. ApaH.
InterProiIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.
TIGRFAMsiTIGR00668. apaH. 1 hit.

Sequencei

Sequence statusi: Complete.

C4L9L6-1 [UniParc]FASTAAdd to Basket

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MATYFVGDIQ GCNDELQQLL ALAQFNPQHD ELWLTGDLVA RGPKSLDVLR    50
FVYGLGDRAT TVLGNHDLNL LAVDAGYSQA KKKDKTENIL TAPDRHELMT 100
WLRTQPIMAE HPTLPVMMTH AGLSPQWDLA TARHCAREVE MLLRSDQGNW 150
LLGHMYGEEP SHWDARLTGL PRWRYIINSF TRMRFCRNDG SLEFKCKEAP 200
SDKPALLAPW FEVRQAAPDE PHLVFGHWAA LMGKCPLPTI KALDTGCVWG 250
NQLTLWRWDD NAMFSLNCPA YASGGE 276
Length:276
Mass (Da):31,187
Last modified:July 7, 2009 - v1
Checksum:i582BDD4D2FD89EC4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001616 Genomic DNA. Translation: ACQ93969.1.
RefSeqiWP_015879437.1. NC_012691.1.
YP_002893555.1. NC_012691.1.

Genome annotation databases

EnsemblBacteriaiACQ93969; ACQ93969; Tola_2372.
GeneIDi7886309.
KEGGitau:Tola_2372.
PATRICi23981407. VBITolAue42623_2356.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001616 Genomic DNA. Translation: ACQ93969.1 .
RefSeqi WP_015879437.1. NC_012691.1.
YP_002893555.1. NC_012691.1.

3D structure databases

ProteinModelPortali C4L9L6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 595494.Tola_2372.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACQ93969 ; ACQ93969 ; Tola_2372 .
GeneIDi 7886309.
KEGGi tau:Tola_2372.
PATRICi 23981407. VBITolAue42623_2356.

Phylogenomic databases

eggNOGi COG0639.
HOGENOMi HOG000251871.
KOi K01525.
OMAi INAFTRM.
OrthoDBi EOG66B3WP.

Enzyme and pathway databases

BioCyci TAUE595494:GHEF-2449-MONOMER.

Family and domain databases

Gene3Di 3.60.21.10. 2 hits.
HAMAPi MF_00199. ApaH.
InterProi IPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
[Graphical view ]
PIRSFi PIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMi SSF56300. SSF56300. 1 hit.
TIGRFAMsi TIGR00668. apaH. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 9187 / TA4.

Entry informationi

Entry nameiAPAH_TOLAT
AccessioniPrimary (citable) accession number: C4L9L6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 7, 2009
Last modified: September 3, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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