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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Tolumonas auensis (strain DSM 9187 / TA4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:Tola_2372
OrganismiTolumonas auensis (strain DSM 9187 / TA4)
Taxonomic identifieri595494 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeTolumonas
Proteomesi
  • UP000009073 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002040901 – 276Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST276

Interactioni

Protein-protein interaction databases

STRINGi595494.Tola_2372

Structurei

3D structure databases

ProteinModelPortaliC4L9L6
SMRiC4L9L6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

C4L9L6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYFVGDIQ GCNDELQQLL ALAQFNPQHD ELWLTGDLVA RGPKSLDVLR
60 70 80 90 100
FVYGLGDRAT TVLGNHDLNL LAVDAGYSQA KKKDKTENIL TAPDRHELMT
110 120 130 140 150
WLRTQPIMAE HPTLPVMMTH AGLSPQWDLA TARHCAREVE MLLRSDQGNW
160 170 180 190 200
LLGHMYGEEP SHWDARLTGL PRWRYIINSF TRMRFCRNDG SLEFKCKEAP
210 220 230 240 250
SDKPALLAPW FEVRQAAPDE PHLVFGHWAA LMGKCPLPTI KALDTGCVWG
260 270
NQLTLWRWDD NAMFSLNCPA YASGGE
Length:276
Mass (Da):31,187
Last modified:July 7, 2009 - v1
Checksum:i582BDD4D2FD89EC4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001616 Genomic DNA Translation: ACQ93969.1
RefSeqiWP_015879437.1, NC_012691.1

Genome annotation databases

EnsemblBacteriaiACQ93969; ACQ93969; Tola_2372
KEGGitau:Tola_2372

Similar proteinsi

Entry informationi

Entry nameiAPAH_TOLAT
AccessioniPrimary (citable) accession number: C4L9L6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 7, 2009
Last modified: March 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health