C4L2X3 (C4L2X3_EXISA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aspartate--ammonia ligase HAMAP MF_00555
EC=6.3.1.1 HAMAP MF_00555

Alternative name(s):
Asparagine synthetase A HAMAP MF_00555

Gene names

Name:	asnA HAMAP MF_00555
Ordered Locus Names:	EAT1b_2325

Organism

Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b) [Complete proteome] [HAMAP] EMBL ACQ71247.1

Taxonomic identifier

360911 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillales Family XII. Incertae Sedis › Exiguobacterium

Protein attributes

Sequence length	326 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine. HAMAP MF_00555
Pathway	Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (ammonia route): step 1/1. HAMAP MF_00555
Subcellular location	Cytoplasm By similarity HAMAP MF_00555.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily. HAMAP MF_00555

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Asparagine biosynthesis HAMAP MF_00555
Cellular component	Cytoplasm HAMAP MF_00555
Ligand	ATP-binding HAMAP MF_00555 Nucleotide-binding
Molecular function	Ligase HAMAP MF_00555 EMBL ACQ71247.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	asparagine biosynthetic process Inferred from electronic annotation. Source: HAMAP tRNA aminoacylation for protein translation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP aminoacyl-tRNA ligase activity Inferred from electronic annotation. Source: InterPro aspartate-ammonia ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C4L2X3 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: 0F3AE4E170368E4A	FASTA	326	36,643
	10 20 30 40 50 60 MTTATSTMKE RQQTIAAVKA LFEEKVSREL GLIQVQAPLF VESASGVNDH LNGVERIIQF 70 80 90 100 110 120 DTMYPGHELE IVQSLAKWKR EALGRYGFGV GEGLYTQMRA IRRDEELDAT HSLFVDQWDW 130 140 150 160 170 180 ERVIAREERT MEYLKATVES IYAALRETEA EVEKTYGVEA ILPEVIHFIT SQELEDSYPT 190 200 210 220 230 240 MTPKERETAI CKEYGAVFIS QIGDLLASGM KHDGRAADYD DWSLNGDILV WHPELESAFE 250 260 270 280 290 300 LSSMGIRVDE VALDAQLKKA DAEEKRAYPF HQGVLEGTLP LTIGGGIGQS RVAMYLLRAR 310 320 HIGEVQTSVW PQEVIQSCKE AGISLL

References

[1]

"Complete sequence of Exiguobacterium sp. AT1b." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G. , Ramaley R.F., Rodrigues D.F., Vishnivetskaya T.A., Kathariou S., Tiedje J.M., Richardson P. Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1283 / AT1b.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001615 Genomic DNA. Translation: ACQ71247.1.
RefSeq	YP_002886692.1. NC_012673.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C4L2X3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7870374.
GenomeReviews	Gene locus EAT1b_2325 in contig CP001615_GR.
KEGG	eat:EAT1b_2325.
PATRIC	21879882. VBIExiSp39724_2305.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	LNDNLNG.
ProtClustDB	PRK05425.
Family and domain databases
HAMAP	MF_00555. AsnA. [Tree]
InterPro	IPR006195. aa-tRNA-synth_II. IPR004618. AsnA. [Graphical view]
KO	K01914.
Pfam	PF03590. AsnA. 1 hit. [Graphical view]
PIRSF	PIRSF001555. Asp_ammon_ligase. 1 hit.
TIGRFAMs	TIGR00669. AsnA. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C4L2X3_EXISA

Accession

Primary (citable) accession number: C4L2X3

Entry history

Integrated into UniProtKB/TrEMBL:	July 7, 2009
Last sequence update:	July 7, 2009
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)