SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C4L2P2

- C4L2P2_EXISA

UniProt

C4L2P2 - C4L2P2_EXISA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Argininosuccinate synthase
Gene
argG, EAT1b_0368
Organism
Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei85 – 851Citrulline By similarityUniRule annotation
Binding sitei115 – 1151ATP; via amide nitrogen By similarityUniRule annotation
Binding sitei117 – 1171Aspartate By similarityUniRule annotation
Binding sitei121 – 1211Aspartate By similarityUniRule annotation
Binding sitei121 – 1211Citrulline By similarityUniRule annotation
Binding sitei122 – 1221Aspartate By similarityUniRule annotation
Binding sitei125 – 1251Citrulline By similarityUniRule annotation
Binding sitei173 – 1731Citrulline By similarityUniRule annotation
Binding sitei258 – 2581Citrulline By similarityUniRule annotation
Binding sitei270 – 2701Citrulline By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 169ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. argininosuccinate synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciESP360911:GI4R-370-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthaseUniRule annotation (EC:6.3.4.5UniRule annotation)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argGUniRule annotation
Ordered Locus Names:EAT1b_0368Imported
OrganismiExiguobacterium sp. (strain ATCC BAA-1283 / AT1b)Imported
Taxonomic identifieri360911 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillales Family XII. Incertae SedisExiguobacterium
ProteomesiUP000000716: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Protein-protein interaction databases

STRINGi360911.EAT1b_0368.

Structurei

3D structure databases

ProteinModelPortaliC4L2P2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiAPPEEAY.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4L2P2-1 [UniParc]FASTAAdd to Basket

« Hide

MKQKLVLAYS GGLDTSVAIK WLDEQGYDVI AVCLNVGEGK DLEKIQQKAM    50
KVGAKKSIVI DAVDEFVNEF ARYSMQAHTL YEGIYPLVSA LSRPLISKKL 100
VEVAQAEGAV AVAHGCTGKG NDQVRFEVSI HALDPSLEIV APVREWKWSR 150
EEEIAYAAKH QIPIPIVQEE PFSIDQNIWG RAIECGILED PWAAPPASAY 200
ELTAALEDTP HEPTYLEIEF KSGVPVAIDG KSQSFTDILK ELNIVAGAHG 250
VGKIDHIENR VVGIKSREVY EAPGAMTLIT AHKALEALTL VREVAHFKPI 300
VEQKLTETIY NGLWYSQLTK ALLAFIDETQ ATVTGTVRMK LYKGQAIVDG 350
RKSPISLYDE ELATYTSADT FDQQAAVGFI KLWGLPTKVQ SEVLMEKGAF 400
VNE 403
Length:403
Mass (Da):44,369
Last modified:July 7, 2009 - v1
Checksum:i81DE9FF1AD22E53B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001615 Genomic DNA. Translation: ACQ69300.1.
RefSeqiWP_012726419.1. NC_012673.1.
YP_002884745.1. NC_012673.1.

Genome annotation databases

EnsemblBacteriaiACQ69300; ACQ69300; EAT1b_0368.
GeneIDi7868483.
KEGGieat:EAT1b_0368.
PATRICi21875830. VBIExiSp39724_0354.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001615 Genomic DNA. Translation: ACQ69300.1 .
RefSeqi WP_012726419.1. NC_012673.1.
YP_002884745.1. NC_012673.1.

3D structure databases

ProteinModelPortali C4L2P2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 360911.EAT1b_0368.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACQ69300 ; ACQ69300 ; EAT1b_0368 .
GeneIDi 7868483.
KEGGi eat:EAT1b_0368.
PATRICi 21875830. VBIExiSp39724_0354.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi APPEEAY.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci ESP360911:GI4R-370-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1283 / AT1b.

Entry informationi

Entry nameiC4L2P2_EXISA
AccessioniPrimary (citable) accession number: C4L2P2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: September 3, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi