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C4L2D6

- C4L2D6_EXISA

UniProt

C4L2D6 - C4L2D6_EXISA

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Protein
Alanine racemase
Gene
EAT1b_2266
Organism
Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei29 – 291Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei121 – 1211Substrate By similarityUniRule annotation
Active sitei249 – 2491Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei296 – 2961Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciESP360911:GI4R-2342-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:EAT1b_2266Imported
OrganismiExiguobacterium sp. (strain ATCC BAA-1283 / AT1b)Imported
Taxonomic identifieri360911 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillales Family XII. Incertae SedisExiguobacterium
ProteomesiUP000000716: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei29 – 291N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi360911.EAT1b_2266.

Structurei

3D structure databases

ProteinModelPortaliC4L2D6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000280025.
KOiK01775.
OMAiAYHYGLE.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

C4L2D6-1 [UniParc]FASTAAdd to Basket

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MGVTIDLNAI RENKRRIEAL GRPVFAVVKN NAYNLGMEPV VTTLYDEGVR    50
HFMVTTLEEA LEVRTHAESA RVLIMNPVYT WEHVHAHDFD VAIGSYEWLV 100
SQREHLDGVR LHLKLDVGMN RFGAKTFEEA LRIVAFCQNE GLNLVGLCTH 150
FPLADADNAE VEHSVQVERF ADWSTRLMER HTFELIHAAN SAATLQDDSR 200
LHHCTHVRVG IFLYGYSSVE PVEWLVPAFY WETEVVAVHD IEAGAHVGYG 250
TGYTAESKER IAVLPVGYGD GLMRARRHLP VHIEGRAYPF VSNIFMSHSF 300
IKVDEDVQIG DRVALYGIET KIDDVTRVGY ANNSEQLCAR SWRVPHRFEG 350
GIVCTPPINQ NV 362
Length:362
Mass (Da):40,918
Last modified:July 7, 2009 - v1
Checksum:iED4BDD942886221C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001615 Genomic DNA. Translation: ACQ71188.1.
RefSeqiWP_015880747.1. NC_012673.1.
YP_002886633.1. NC_012673.1.

Genome annotation databases

EnsemblBacteriaiACQ71188; ACQ71188; EAT1b_2266.
GeneIDi7870853.
KEGGieat:EAT1b_2266.
PATRICi21879750. VBIExiSp39724_2242.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001615 Genomic DNA. Translation: ACQ71188.1 .
RefSeqi WP_015880747.1. NC_012673.1.
YP_002886633.1. NC_012673.1.

3D structure databases

ProteinModelPortali C4L2D6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 360911.EAT1b_2266.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACQ71188 ; ACQ71188 ; EAT1b_2266 .
GeneIDi 7870853.
KEGGi eat:EAT1b_2266.
PATRICi 21879750. VBIExiSp39724_2242.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000280025.
KOi K01775.
OMAi AYHYGLE.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci ESP360911:GI4R-2342-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1283 / AT1b.

Entry informationi

Entry nameiC4L2D6_EXISA
AccessioniPrimary (citable) accession number: C4L2D6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: September 3, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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