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C4L2D6

- C4L2D6_EXISA

UniProt

C4L2D6 - C4L2D6_EXISA

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Protein

Alanine racemase

Gene

EAT1b_2266

Organism
Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei29 – 291Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei121 – 1211SubstrateUniRule annotation
Active sitei249 – 2491Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei296 – 2961Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciESP360911:GI4R-2342-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:EAT1b_2266Imported
OrganismiExiguobacterium sp. (strain ATCC BAA-1283 / AT1b)Imported
Taxonomic identifieri360911 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillales Family XII. Incertae SedisExiguobacterium
ProteomesiUP000000716: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei29 – 291N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi360911.EAT1b_2266.

Structurei

3D structure databases

ProteinModelPortaliC4L2D6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000280025.
KOiK01775.
OMAiAYHYGLE.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

C4L2D6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGVTIDLNAI RENKRRIEAL GRPVFAVVKN NAYNLGMEPV VTTLYDEGVR
60 70 80 90 100
HFMVTTLEEA LEVRTHAESA RVLIMNPVYT WEHVHAHDFD VAIGSYEWLV
110 120 130 140 150
SQREHLDGVR LHLKLDVGMN RFGAKTFEEA LRIVAFCQNE GLNLVGLCTH
160 170 180 190 200
FPLADADNAE VEHSVQVERF ADWSTRLMER HTFELIHAAN SAATLQDDSR
210 220 230 240 250
LHHCTHVRVG IFLYGYSSVE PVEWLVPAFY WETEVVAVHD IEAGAHVGYG
260 270 280 290 300
TGYTAESKER IAVLPVGYGD GLMRARRHLP VHIEGRAYPF VSNIFMSHSF
310 320 330 340 350
IKVDEDVQIG DRVALYGIET KIDDVTRVGY ANNSEQLCAR SWRVPHRFEG
360
GIVCTPPINQ NV
Length:362
Mass (Da):40,918
Last modified:July 7, 2009 - v1
Checksum:iED4BDD942886221C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001615 Genomic DNA. Translation: ACQ71188.1.
RefSeqiWP_015880747.1. NC_012673.1.
YP_002886633.1. NC_012673.1.

Genome annotation databases

EnsemblBacteriaiACQ71188; ACQ71188; EAT1b_2266.
GeneIDi7870853.
KEGGieat:EAT1b_2266.
PATRICi21879750. VBIExiSp39724_2242.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001615 Genomic DNA. Translation: ACQ71188.1 .
RefSeqi WP_015880747.1. NC_012673.1.
YP_002886633.1. NC_012673.1.

3D structure databases

ProteinModelPortali C4L2D6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 360911.EAT1b_2266.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACQ71188 ; ACQ71188 ; EAT1b_2266 .
GeneIDi 7870853.
KEGGi eat:EAT1b_2266.
PATRICi 21879750. VBIExiSp39724_2242.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000280025.
KOi K01775.
OMAi AYHYGLE.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci ESP360911:GI4R-2342-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1283 / AT1bImported.

Entry informationi

Entry nameiC4L2D6_EXISA
AccessioniPrimary (citable) accession number: C4L2D6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: November 26, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3