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C4L2C1 (GLSA_EXISA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:EAT1b_2251
OrganismExiguobacterium sp. (strain ATCC BAA-1283 / AT1b) [Complete proteome] [HAMAP]
Taxonomic identifier360911 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillales Family XII. Incertae SedisExiguobacterium

Protein attributes

Sequence length313 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 313313Glutaminase HAMAP-Rule MF_00313
PRO_1000205062

Sites

Binding site641Substrate By similarity
Binding site1161Substrate By similarity
Binding site1631Substrate By similarity
Binding site1701Substrate By similarity
Binding site1941Substrate By similarity
Binding site2461Substrate By similarity
Binding site2641Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
C4L2C1 [UniParc].

Last modified July 7, 2009. Version 1.
Checksum: 04450E14AA9367DC

FASTA31334,412
        10         20         30         40         50         60 
MNVLEQQLNH LVDECRPYTA QGKVADYIPE LAHVKNDLLG VAICLPDGTY IHAGDVHHKF 

        70         80         90        100        110        120 
TIQSVSKALT LCYVLMEFGE DYVFSKVGME PTGDAFNSIA KLEETVPSKP LNPMINAGAL 

       130        140        150        160        170        180 
AVTSMILGET AELKIYQFRQ FLATLLNRSV EEVTYDEKVA RSEYETTDLN RALLYFMRHH 

       190        200        210        220        230        240 
GIVEGDVDEI IDVYTKQCAI EIDCFDLARI GRVFAGNGED PDTGEELIPR RVVRIVKAIM 

       250        260        270        280        290        300 
TTCGMYDASG EFAVRVGLPG KSGVSGAILA VGNHELDLNN VGFGIFGPAL DSKGNSIAGM 

       310 
KLLELLIERY TSR 

« Hide

References

[1]"Complete sequence of Exiguobacterium sp. AT1b."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G. expand/collapse author list , Ramaley R.F., Rodrigues D.F., Vishnivetskaya T.A., Kathariou S., Tiedje J.M., Richardson P.
Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1283 / AT1b.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001615 Genomic DNA. Translation: ACQ71173.1.
RefSeqYP_002886618.1. NC_012673.1.

3D structure databases

ProteinModelPortalC4L2C1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING360911.EAT1b_2251.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACQ71173; ACQ71173; EAT1b_2251.
GeneID7870838.
KEGGeat:EAT1b_2251.
PATRIC21879720. VBIExiSp39724_2227.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMARINALML.
OrthoDBEOG6N94BK.
ProtClustDBCLSK2488972.

Enzyme and pathway databases

BioCycESP360911:GI4R-2327-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_EXISA
AccessionPrimary (citable) accession number: C4L2C1
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 7, 2009
Last modified: February 19, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families