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C4L274 (MTLD_EXISA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannitol-1-phosphate 5-dehydrogenase
EC=1.1.1.17
Gene names
Name:mtlD
Ordered Locus Names:EAT1b_2204
OrganismExiguobacterium sp. (strain ATCC BAA-1283 / AT1b) [Complete proteome] [HAMAP]
Taxonomic identifier360911 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillales Family XII. Incertae Sedis › Exiguobacterium

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196

Sequence similarities

Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

mannitol-1-phosphate 5-dehydrogenase activity

Inferred from electronic annotation. Source: EC

nucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 382382Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196
PRO_1000204052

Regions

Nucleotide binding3 – 1412NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
C4L274 [UniParc].

Last modified July 7, 2009. Version 1.
Checksum: B2C1E1C639BA8BB9

FASTA38242,639
        10         20         30         40         50         60 
MKAVHFGAGN IGRGFIGLLL NQSGYEVTFV DINDTVIEAL EVKRHYEVGF AEDGVDRIVV 

        70         80         90        100        110        120 
DRVRGVNSLK EPARVVDLIA EADLVTTAVG PSLLSKVAPL ISEGLRAREV EDAPVYVIAC 

       130        140        150        160        170        180 
ENMIGGSAIL RQEVEACGGV GEANVFFPNA AVDRIVPLQQ HEDPLYVEVE TFHEWVIETQ 

       190        200        210        220        230        240 
GLNEQPPIQG VTWVEEIGPY IERKLFTVNT GHAIASYIGS LFGKATIDEA LKDRRVRQVV 

       250        260        270        280        290        300 
QGALYETGWL LLEKYGFEAK EHSQYIQKII KRFENPKLKD EVSRVARSPI RKLGPSDRLV 

       310        320        330        340        350        360 
KPARELMDNG IEPNELAYGI AAALHYYNPE DSESSELNLS IEEHGISSTI EKYLHLHEGD 

       370        380 
TLTQLILDQY HLIREEEKER VS

« Hide

References

[1]"Complete sequence of Exiguobacterium sp. AT1b."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G. expand/collapse author list , Ramaley R.F., Rodrigues D.F., Vishnivetskaya T.A., Kathariou S., Tiedje J.M., Richardson P.
Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1283 / AT1b.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001615 Genomic DNA. Translation: ACQ71126.1.
RefSeqYP_002886571.1. NC_012673.1.

3D structure databases

ProteinModelPortalC4L274.
ModBaseSearch...

Protein-protein interaction databases

STRINGC4L274.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7869592.
GenomeReviewsGene locus EAT1b_2204 in contig CP001615_GR.
KEGGeat:EAT1b_2204.
PATRIC21879602. VBIExiSp39724_2180.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAFANTAVD.
ProtClustDBCLSK2489393.

Family and domain databases

HAMAPMF_00196. Mannitol_dehydrog.
[Tree]
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR023028. Mannitol_1_phos_5_DH.
IPR000669. Mannitol_DH.
IPR013118. Mannitol_DH_C.
IPR023027. Mannitol_DH_CS.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00009.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00974. MANNITOL_DHGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTLD_EXISA
AccessionPrimary (citable) accession number: C4L274
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 7, 2009
Last modified: January 25, 2012
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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