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Protein

Ornithine carbamoyltransferase

Gene

EAT1b_2070

Organism
Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.SAAS annotation

Catalytic activityi

Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei81Carbamoyl phosphateUniRule annotation1
Binding sitei105Carbamoyl phosphateUniRule annotation1
Binding sitei163OrnithineUniRule annotation1
Binding sitei227OrnithineUniRule annotation1
Binding sitei295Carbamoyl phosphateUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseUniRule annotationSAAS annotationImported

Enzyme and pathway databases

BioCyciESP360911:G1GVI-2096-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ornithine carbamoyltransferaseSAAS annotation (EC:2.1.3.3SAAS annotation)
Gene namesi
Ordered Locus Names:EAT1b_2070Imported
OrganismiExiguobacterium sp. (strain ATCC BAA-1283 / AT1b)Imported
Taxonomic identifieri360911 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillales Family XII. Incertae SedisExiguobacterium
Proteomesi
  • UP000000716 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi360911.EAT1b_2070

Structurei

3D structure databases

ProteinModelPortaliC4L130
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 145OTCace_NInterPro annotationAdd BLAST139
Domaini152 – 305OTCaceInterPro annotationAdd BLAST154

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni54 – 57Carbamoyl phosphate bindingUniRule annotation4
Regioni132 – 135Carbamoyl phosphate bindingUniRule annotation4
Regioni231 – 232Ornithine bindingUniRule annotation2
Regioni267 – 268Carbamoyl phosphate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the ATCase/OTCase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DBV Bacteria
COG0078 LUCA
HOGENOMiHOG000022686
KOiK00611
OMAiDGNNVCN
OrthoDBiPOG091H0543

Family and domain databases

Gene3Di3.40.50.1370, 2 hits
HAMAPiMF_01109 OTCase, 1 hit
InterProiView protein in InterPro
IPR006132 Asp/Orn_carbamoyltranf_P-bd
IPR006130 Asp/Orn_carbamoylTrfase
IPR036901 Asp/Orn_carbamoylTrfase_sf
IPR006131 Asp_carbamoyltransf_Asp/Orn-bd
IPR002292 Orn/put_carbamltrans
IPR024904 OTCase_ArgI
PfamiView protein in Pfam
PF00185 OTCace, 1 hit
PF02729 OTCace_N, 1 hit
PRINTSiPR00100 AOTCASE
PR00102 OTCASE
SUPFAMiSSF53671 SSF53671, 1 hit
TIGRFAMsiTIGR00658 orni_carb_tr, 1 hit
PROSITEiView protein in PROSITE
PS00097 CARBAMOYLTRANSFERASE, 1 hit

Sequencei

Sequence statusi: Complete.

C4L130-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVKTIQHFL TMEELTPDTL DSLMQLAHEV KRSPQSYATA LTGKKVALLF
60 70 80 90 100
EKASTRTRMS FEVGVVELGG YPLFLSGQDL QIGRGEPLTD TIQVMSRYVD
110 120 130 140 150
ALMIRTYAHE TVETLAQHGS IPIINGLTDL HHPCQVLADL LTIEEQFGSR
160 170 180 190 200
AGKVLAYIGD GNNMAHSLMI GGALSGMHIR IASPNGYTVD HAIYEKAQKL
210 220 230 240 250
ATSTGGSIAL FENPSLAANE ADIVYTDVFA SMGQEGEAEE RLMKFNGFQV
260 270 280 290 300
NKELMALANP DAIFLHCLPA HRGEEVTADV IDGPQSWVFD QAENRLHAQK

ALMLTLLT
Length:308
Mass (Da):33,672
Last modified:July 7, 2009 - v1
Checksum:iC4F5365611E25102
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001615 Genomic DNA Translation: ACQ70993.1
RefSeqiWP_015880552.1, NC_012673.1

Genome annotation databases

EnsemblBacteriaiACQ70993; ACQ70993; EAT1b_2070
KEGGieat:EAT1b_2070

Similar proteinsi

Entry informationi

Entry nameiC4L130_EXISA
AccessioniPrimary (citable) accession number: C4L130
Entry historyiIntegrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: March 28, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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