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C4L0Z5 (SYR_EXISA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:EAT1b_2035
OrganismExiguobacterium sp. (strain ATCC BAA-1283 / AT1b) [Complete proteome] [HAMAP]
Taxonomic identifier360911 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillales Family XII. Incertae SedisExiguobacterium

Protein attributes

Sequence length560 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 560560Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000203095

Regions

Motif121 – 13111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
C4L0Z5 [UniParc].

Last modified July 7, 2009. Version 1.
Checksum: 4740E3A6F126438A

FASTA56063,311
        10         20         30         40         50         60 
MSYERKYAEA LSRVIGEELT IDQIEALIEK PKHEAHGDLA FPCFQLAKAY RKAPVMIATD 

        70         80         90        100        110        120 
IANELNDELF TKVEAAGPYV NVFLSRDVVS KEIINTVLEE KSEYATHEAR NETIVTDFSS 

       130        140        150        160        170        180 
PNIAKPFSMG HLRSTVIGNA INQIARKNGY DVVGVNHLGD WGTQFGKLMV AYKKWGDEEA 

       190        200        210        220        230        240 
VRANPIAELL KLYVHFHEEA KTQPELEDEG RAWFKKLEDG DAEATELWQW FRDESLKEFQ 

       250        260        270        280        290        300 
KVYDLLGVKF ESFNGEAFYN DKMGRVVEML EAKNLLVESE GAMVVSLEEE NLPPCLIKKK 

       310        320        330        340        350        360 
DGATLYATRD LAAAIYRYET YNFVQANYVV GGEQALHFKQ LFSVLRKLGY DFVDGMHHVP 

       370        380        390        400        410        420 
FGLILQEGKK MSTRKGRIVL LEEVLKEAIE KAQANIEQKN PDLANAQDVA RMVGVGAVVF 

       430        440        450        460        470        480 
HDLKNERINN IEFDLDSMLK FEGETGPYVQ YTNARANSLL RKGNYDGSPF TGADDDYSWG 

       490        500        510        520        530        540 
VVTMLNAFPH VITRAHERRE PSIISRYVLD LAQAFNKYYG HVRVLEEDAG KQSRLALVKA 

       550        560 
VTLVLTEGLR LLGVEAPEEM 

« Hide

References

[1]"Complete sequence of Exiguobacterium sp. AT1b."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G. expand/collapse author list , Ramaley R.F., Rodrigues D.F., Vishnivetskaya T.A., Kathariou S., Tiedje J.M., Richardson P.
Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1283 / AT1b.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001615 Genomic DNA. Translation: ACQ70958.1.
RefSeqYP_002886403.1. NC_012673.1.

3D structure databases

ProteinModelPortalC4L0Z5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING360911.EAT1b_2035.

Proteomic databases

PRIDEC4L0Z5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACQ70958; ACQ70958; EAT1b_2035.
GeneID7868842.
KEGGeat:EAT1b_2035.
PATRIC21879240. VBIExiSp39724_2014.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247211.
KOK01887.
OMAKVNGMST.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycESP360911:GI4R-2084-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_EXISA
AccessionPrimary (citable) accession number: C4L0Z5
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 7, 2009
Last modified: May 14, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries