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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciESP360911:G1GVI-1692-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:EAT1b_1686
OrganismiExiguobacterium sp. (strain ATCC BAA-1283 / AT1b)
Taxonomic identifieri360911 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillales Family XII. Incertae SedisExiguobacterium
Proteomesi
  • UP000000716 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002025841 – 185Peptidyl-tRNA hydrolaseAdd BLAST185

Proteomic databases

PRIDEiC4KZU9

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi360911.EAT1b_1686

Structurei

3D structure databases

SMRiC4KZU9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH
OrthoDBiPOG091H02CU

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

C4KZU9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKCIVGLGNP GKKFEMTRHN VGFLAIDRLA EKHGISLNEA KFNALMGTGR
60 70 80 90 100
INGERVVLVK PLTYMNLSGE AVRPILDYYK IEIDDLLVIY DDLDMVPGKL
110 120 130 140 150
RFRPKGSAGG HNGIKSLIQH LGTAEFKRLK LGIGRPPHPI KVVDWVLMNY
160 170 180
RKDELPELNE TLDNAVTAAT DFVDTDWLAL MNRYN
Length:185
Mass (Da):20,789
Last modified:July 7, 2009 - v1
Checksum:iCB977B06E2F9929C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001615 Genomic DNA Translation: ACQ70612.1
RefSeqiWP_012727730.1, NC_012673.1

Genome annotation databases

EnsemblBacteriaiACQ70612; ACQ70612; EAT1b_1686
GeneIDi32211266
KEGGieat:EAT1b_1686

Similar proteinsi

Entry informationi

Entry nameiPTH_EXISA
AccessioniPrimary (citable) accession number: C4KZU9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 7, 2009
Last modified: May 23, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health