C4KS50 (C4KS50_BURPE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
D-amino acid dehydrogenase small subunit HAMAP-Rule MF_01202
EC=1.4.99.1 HAMAP-Rule MF_01202

Gene names

Name:	dadA HAMAP-Rule MF_01202
ORF Names:	GBP346_A3044 EMBL ACQ97197.1

Organism

Burkholderia pseudomallei MSHR346 EMBL ACQ97197.1

Taxonomic identifier

536230 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group › Burkholderia pseudomallei

Protein attributes

Sequence length	428 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity. HAMAP-Rule MF_01202 SAAS SAAS006076
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP-Rule MF_01202 SAAS SAAS006076
Cofactor	FAD By similarity. HAMAP-Rule MF_01202 SAAS SAAS006076
Pathway	Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP-Rule MF_01202
Subunit structure	Heterodimer of a small and a large subunit By similarity. HAMAP-Rule MF_01202 SAAS SAAS006076
Sequence similarities	Belongs to the DadA oxidoreductase family. HAMAP-Rule MF_01202

Ontologies

Keywords
Ligand	FAD HAMAP-Rule MF_01202 SAAS SAAS006076 Flavoprotein HAMAP-Rule MF_01202 SAAS SAAS006076
Molecular function	Oxidoreductase HAMAP-Rule MF_01202 SAAS SAAS006076 EMBL ACQ97197.1
Gene Ontology (GO)
Biological_process	D-alanine catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	3 – 17	15	FAD By similarity HAMAP-Rule MF_01202

Sequences

	Sequence		Length	Mass (Da)
	C4KS50 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: 0AC24145CC22B8EE	FASTA	428	46,175
	10 20 30 40 50 60 MRVVILGSGV VGVASAYYLA RAGHEVTVID REAGPALDTS FANAGQISPG YAAPWAAPGV 70 80 90 100 110 120 PLKAVKWMFE KHAPLAIRLD GTRFQLQWMW QMLRNCTTER YALNKGRMVR LAEYSRDCLQ 130 140 150 160 170 180 ALRAETAIQY EGRTGGTLQV FRTQQQLDGA AKDIAVLREA NVPFELLSSD ELKKAEPALA 190 200 210 220 230 240 AVSHKLTGGL RLPGDETGDC QLFTTRLAAL AEQLGVKFRF NTRIDALAVA GGKIAGVQCG 250 260 270 280 290 300 GEMVRADAYV VALGSYSTNL VASLVKIPVY PLKGYSITAP IVDAAKAPVS TVLDETYKIA 310 320 330 340 350 360 ITRFDDRIRV GGMAEIVGFD KRLRDARRGT LEMCVNDLFP GGGDTAKATF WTGLRPMTPD 370 380 390 400 410 420 GTPIVGRTPV PNLFLNTGHG TLGWTMSCGS GQLLADLMSG KKPAIRADDL SVHRYLSETD GEHRPAYA

References

[1]	Harkins D.M., Brinkac L.M., Rogers Y.C., Detter J.C., Munk A.C., Bruce D.C., Keim P., Sims D.R., Brettin T.S. Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: MSHR346 EMBL ACQ97197.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001408 Genomic DNA. Translation: ACQ97197.1.
RefSeq	YP_002897728.1. NC_012695.1.
3D structure databases
ProteinModelPortal	C4KS50.
ModBase	Search...
Protein-protein interaction databases
STRING	536230.GBP346_A3044.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACQ97197; ACQ97197; GBP346_A3044.
GeneID	7888565.
KEGG	bpr:GBP346_A3044.
PATRIC	32574949. VBIBurPse130472_2783.
Phylogenomic databases
eggNOG	COG0665.
HOGENOM	HOG000217450.
KO	K00285.
ProtClustDB	PRK00711.
Enzyme and pathway databases
BioCyc	BPSE536230:GHVQ-3064-MONOMER.
UniPathway	UPA00043; UER00498.
Family and domain databases
Gene3D	3.40.50.720. 3 hits.
HAMAP	MF_01202. DadA.
InterPro	IPR023080. D-aa_DH_ssu_DadA. IPR006076. FAD-dep_OxRdtase. IPR016040. NAD(P)-bd_dom. [Graphical view]
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C4KS50_BURPE

Accession

Primary (citable) accession number: C4KS50

Entry history

Integrated into UniProtKB/TrEMBL:	July 7, 2009
Last sequence update:	July 7, 2009
Last modified:	April 3, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)