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C4KRQ9 (C4KRQ9_BURPE) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-deoxy-manno-octulosonate cytidylyltransferase HAMAP-Rule MF_00057
EC=2.7.7.38 HAMAP-Rule MF_00057
Alternative name(s):
CMP-2-keto-3-deoxyoctulosonic acid synthase HAMAP-Rule MF_00057
Gene names
Name:kdsB HAMAP-Rule MF_00057 EMBL ACQ98250.1
ORF Names:GBP346_A0851 EMBL ACQ98250.1
OrganismBurkholderia pseudomallei MSHR346 EMBL ACQ98250.1
Taxonomic identifier536230 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group ›

Protein attributes

Sequence length263 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria By similarity. HAMAP-Rule MF_00057 SAAS SAAS003329

Catalytic activity

CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate. HAMAP-Rule MF_00057 SAAS SAAS003329

Pathway

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. SAAS SAAS003329

Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1. HAMAP-Rule MF_00057 SAAS SAAS003329

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00057 SAAS SAAS003329.

Sequence similarities

Belongs to the KdsB family. HAMAP-Rule MF_00057

Sequences

Sequence LengthMass (Da)Tools
C4KRQ9 [UniParc].

Last modified July 7, 2009. Version 1.
Checksum: 5A4CC93F0C4E2AEA

FASTA26328,758
        10         20         30         40         50         60 
MTSPLPFVAV VPARLASTRL PNKPLADLGG KPMVVRVAER AREAGAQQVL VASDAQRVLD 

        70         80         90        100        110        120 
AVREHGFDAV LTRADHPSGT DRLAEVAAKL GFDDDTIVVN VQGDEPLIDP QLVRDVASHL 

       130        140        150        160        170        180 
AAHPSCAIAT AAHPIHEAHE VFNPNYVKVV LDAHGVALYF SRAPIPWSRD AYLPHWPNVA 

       190        200        210        220        230        240 
AMPAPTCPVY RHIGLYAYRA RFLRTYPTLA QAPIEAAEQL EQLRAMWHGE RIAVRVTEHA 

       250        260 
PEAGIDTPAD LERVQALFRS RAK

« Hide

References

[1]Harkins D.M., Brinkac L.M., Rogers Y.C., Detter J.C., Munk A.C., Bruce D.C., Keim P., Sims D.R., Brettin T.S.
Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MSHR346 EMBL ACQ98250.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001408 Genomic DNA. Translation: ACQ98250.1.
RefSeqYP_002895575.1. NC_012695.1.

3D structure databases

ProteinModelPortalC4KRQ9.
SMRC4KRQ9. Positions 6-257.
ModBaseSearch...

Protein-protein interaction databases

STRING536230.GBP346_A0851.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACQ98250; ACQ98250; GBP346_A0851.
GeneID7887625.
KEGGbpr:GBP346_A0851.
PATRIC32570893. VBIBurPse130472_0786.

Phylogenomic databases

eggNOGCOG1212.
HOGENOMHOG000007602.
KOK00979.
ProtClustDBPRK05450.

Enzyme and pathway databases

BioCycBPSE536230:GHVQ-911-MONOMER.
UniPathwayUPA00030.
UPA00358; UER00476.

Family and domain databases

HAMAPMF_00057. CMP_KDO_synth.
InterProIPR003329. Cytidylyl_trans.
IPR004528. KdsB.
[Graphical view]
PANTHERPTHR21485:SF4. PTHR21485:SF4. 1 hit.
PfamPF02348. CTP_transf_3. 1 hit.
[Graphical view]
TIGRFAMsTIGR00466. kdsB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC4KRQ9_BURPE
AccessionPrimary (citable) accession number: C4KRQ9
Entry history
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: April 3, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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