C4KP90 (C4KP90_BURPE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277
Short name=PII uridylyl-transferase HAMAP-Rule MF_00277
EC=2.7.7.59 HAMAP-Rule MF_00277

Alternative name(s):
UTase HAMAP-Rule MF_00277
Uridylyl-removing enzyme HAMAP-Rule MF_00277

Gene names

Name:	glnD HAMAP-Rule MF_00277 EMBL ACQ95234.1
ORF Names:	GBP346_A2565 EMBL ACQ95234.1

Organism

Burkholderia pseudomallei MSHR346 EMBL ACQ95234.1

Taxonomic identifier

536230 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group › Burkholderia pseudomallei

Protein attributes

Sequence length	858 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277 SAAS SAAS010043
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277 SAAS SAAS010043
Sequence similarities	Belongs to the GlnD family. HAMAP-Rule MF_00277

Ontologies

Keywords
Molecular function	Nucleotidyltransferase HAMAP-Rule MF_00277 SAAS SAAS010043 EMBL ACQ95234.1 Transferase
Gene Ontology (GO)
Biological_process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C4KP90 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: E71C618DBA6FE7F4	FASTA	858	96,750
	10 20 30 40 50 60 MSASVAEPPP ALSRKAEFKA AKAELLARFK SANHVTPLMH ALSRATDDAL RSLWQECGLP 70 80 90 100 110 120 ATLALVAVGG FGRGELSPHS DVDILVLLPD AHASELDERI ERFIGMAWDL GLEIGSSVRT 130 140 150 160 170 180 VDQCIEEASH DVTVQTSLLE ARRIVGSTAL FERFMLRYRE ALDARAFFQA KVLEMRQRHA 190 200 210 220 230 240 KFQDTPYSLE PNVKESPGGL RDLQTILWIA RAAGFGSSWR ELDTRGLITD REARELRRNE 250 260 270 280 290 300 GFLKTLRARL HVIAGRRQDI LVFDLQTQAA ESFGYQPTSA KRASEQLMRR YYWAAKAVTQ 310 320 330 340 350 360 LATILIQNIE AQLFPATSGV TRVLSPGRFV EKQGMLEIAA DDVFERHPDA ILEAFLLYEA 370 380 390 400 410 420 TRGVKGLSAR TLRALYNSRD VMNNAWRRDP RNRHTFMQIL QQPEGITHAF RLMNQTSVLG 430 440 450 460 470 480 RYLLNFRRIV GQMQHDLYHV YTVDQHILMV LRNIRRFAVA EHAHEYPFCS QLIVNFERPW 490 500 510 520 530 540 VLYVAALFHD IAKGRGGDHS ALGMADARRF CREHGIEGDD AALVVWLVQH HLTMSQVAQK 550 560 570 580 590 600 QDTSDPVVIK RFAELVGSER RLTALYLLTV ADIRGTSPKV WNTWKGKLLE DLYRATLAVL 610 620 630 640 650 660 GGAQPDAHSE LKTRQEEALA LLRLETVPPD AHRALWDQLD VGYFLRHDAA DIAWQTRVLY 670 680 690 700 710 720 RHVAADTAIV RARPSPVGDA LQVLVYVKDR SDLFAGICAY FDRNGLSVLD ARVNTTRHGY 730 740 750 760 770 780 ALDNFIVTQT EHDVQYRDIA NLVEQQLAAR LAESAPLPEP SKGRLSRLSR TFPITPRVDL 790 800 810 820 830 840 RADERGQYYI LSVSANDRPG LLYSIARVLA EHRVGVHAAR INTLGERVED VFMLDGTGLS 850 DNRLQIQVET ELLRAIAV

References

[1]	Harkins D.M., Brinkac L.M., Rogers Y.C., Detter J.C., Munk A.C., Bruce D.C., Keim P., Sims D.R., Brettin T.S. Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: MSHR346 EMBL ACQ95234.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001408 Genomic DNA. Translation: ACQ95234.1.
RefSeq	YP_002897262.1. NC_012695.1.
3D structure databases
ProteinModelPortal	C4KP90.
ModBase	Search...
Protein-protein interaction databases
STRING	536230.GBP346_A2565.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACQ95234; ACQ95234; GBP346_A2565.
GeneID	7887285.
KEGG	bpr:GBP346_A2565.
PATRIC	32574039. VBIBurPse130472_2341.
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261778.
KO	K00990.
ProtClustDB	PRK03059.
Enzyme and pathway databases
BioCyc	BPSE536230:GHVQ-2598-MONOMER.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl_transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C4KP90_BURPE

Accession

Primary (citable) accession number: C4KP90

Entry history

Integrated into UniProtKB/TrEMBL:	July 7, 2009
Last sequence update:	July 7, 2009
Last modified:	May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)