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C4K8I7 (G6PI_HAMD5) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:HDEF_0049
OrganismHamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT) [Complete proteome] [HAMAP]
Taxonomic identifier572265 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeaphid secondary symbiontsCandidatus Hamiltonella

Protein attributes

Sequence length548 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 548548Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_1000206367

Sites

Active site3861 By similarity
Active site5141 By similarity

Sequences

Sequence LengthMass (Da)Tools
C4K8I7 [UniParc].

Last modified July 7, 2009. Version 1.
Checksum: 2C3030059A9E4F4C

FASTA54861,525
        10         20         30         40         50         60 
MKKINPTQTS AWKALQQHFK EIEPIHIRHL FHADPKRSEK FSLTFNDLIR VDFSKNRLTA 

        70         80         90        100        110        120 
QTIEKLQALA QETDLALAIC SMFSGGKINE TEERPVLHIA LRNRGNQPIL VDGQDVMPLV 

       130        140        150        160        170        180 
NAVLEKMKRF CHQVIKGDWN GYSGQTITDV VNIGIGGSDL GPYMATEALK PYKNHLKMHF 

       190        200        210        220        230        240 
VSNVDGTDIV ETLKALNPAR TLFIVASKTF TTQETMTNAQ TAREWFLKTA GDSAHVARHF 

       250        260        270        280        290        300 
VALSTNIKEV TNFGIDPENS FEFWDWVGGR YSLWSAIGLP IALSIGFDNF EKLLEGAYEM 

       310        320        330        340        350        360 
DQHFLKTDFT HNIPVILALI GIWYSHFFGA ETEAVLPYDQ YLHRFPAYLQ QASMESNGKW 

       370        380        390        400        410        420 
VDRDGKPVGY QTGSILWGEP GTNGQHAFYQ LIHQGTKIIP CDFIAPVISH NAIGDHHHKL 

       430        440        450        460        470        480 
LANFFAQTQA LAFGKTEQEV QEELMAEGVF SEKATYLAPF KAFSGNRPTN SILLKQITPL 

       490        500        510        520        530        540 
SLGALIALYE HKIFTQGVIL NIFSFDQWGV ELGKKLASGI LSELEGPEKV SCHDSSTNSL 


INCFKKWH 

« Hide

References

[1]"Hamiltonella defensa, genome evolution of protective bacterial endosymbiont from pathogenic ancestors."
Degnan P.H., Yu Y., Sisneros N., Wing R.A., Moran N.A.
Proc. Natl. Acad. Sci. U.S.A. 106:9063-9068(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 5AT.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001277 Genomic DNA. Translation: ACQ66824.1.
RefSeqYP_002922972.1. NC_012751.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING572265.HDEF_0049.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACQ66824; ACQ66824; HDEF_0049.
GeneID7949654.
KEGGhde:HDEF_0049.
PATRIC31971504. VBICanHam112931_0048.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
KOK01810.
OMALKMHFVS.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycHDEF572265:GJAB-49-MONOMER.
UniPathwayUPA00109; UER00181.
UPA00138.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_HAMD5
AccessionPrimary (citable) accession number: C4K8I7
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 7, 2009
Last modified: February 19, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways