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C4K8I7

- G6PI_HAMD5

UniProt

C4K8I7 - G6PI_HAMD5

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei386 – 3861UniRule annotation
Active sitei514 – 5141UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciHDEF572265:GJAB-49-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:HDEF_0049
OrganismiHamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)
Taxonomic identifieri572265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeaphid secondary symbiontsCandidatus Hamiltonella
ProteomesiUP000002334: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 548548Glucose-6-phosphate isomerasePRO_1000206367Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi572265.HDEF_0049.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4K8I7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKINPTQTS AWKALQQHFK EIEPIHIRHL FHADPKRSEK FSLTFNDLIR
60 70 80 90 100
VDFSKNRLTA QTIEKLQALA QETDLALAIC SMFSGGKINE TEERPVLHIA
110 120 130 140 150
LRNRGNQPIL VDGQDVMPLV NAVLEKMKRF CHQVIKGDWN GYSGQTITDV
160 170 180 190 200
VNIGIGGSDL GPYMATEALK PYKNHLKMHF VSNVDGTDIV ETLKALNPAR
210 220 230 240 250
TLFIVASKTF TTQETMTNAQ TAREWFLKTA GDSAHVARHF VALSTNIKEV
260 270 280 290 300
TNFGIDPENS FEFWDWVGGR YSLWSAIGLP IALSIGFDNF EKLLEGAYEM
310 320 330 340 350
DQHFLKTDFT HNIPVILALI GIWYSHFFGA ETEAVLPYDQ YLHRFPAYLQ
360 370 380 390 400
QASMESNGKW VDRDGKPVGY QTGSILWGEP GTNGQHAFYQ LIHQGTKIIP
410 420 430 440 450
CDFIAPVISH NAIGDHHHKL LANFFAQTQA LAFGKTEQEV QEELMAEGVF
460 470 480 490 500
SEKATYLAPF KAFSGNRPTN SILLKQITPL SLGALIALYE HKIFTQGVIL
510 520 530 540
NIFSFDQWGV ELGKKLASGI LSELEGPEKV SCHDSSTNSL INCFKKWH
Length:548
Mass (Da):61,525
Last modified:July 7, 2009 - v1
Checksum:i2C3030059A9E4F4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001277 Genomic DNA. Translation: ACQ66824.1.
RefSeqiYP_002922972.1. NC_012751.1.

Genome annotation databases

EnsemblBacteriaiACQ66824; ACQ66824; HDEF_0049.
GeneIDi7949654.
KEGGihde:HDEF_0049.
PATRICi31971504. VBICanHam112931_0048.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001277 Genomic DNA. Translation: ACQ66824.1 .
RefSeqi YP_002922972.1. NC_012751.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 572265.HDEF_0049.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACQ66824 ; ACQ66824 ; HDEF_0049 .
GeneIDi 7949654.
KEGGi hde:HDEF_0049.
PATRICi 31971504. VBICanHam112931_0048.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci HDEF572265:GJAB-49-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Hamiltonella defensa, genome evolution of protective bacterial endosymbiont from pathogenic ancestors."
    Degnan P.H., Yu Y., Sisneros N., Wing R.A., Moran N.A.
    Proc. Natl. Acad. Sci. U.S.A. 106:9063-9068(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 5AT.

Entry informationi

Entry nameiG6PI_HAMD5
AccessioniPrimary (citable) accession number: C4K8I7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 7, 2009
Last modified: November 26, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3