C4K639 (C4K639_HAMD5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB 1 HAMAP MF_01400
EC=1.8.4.12 HAMAP MF_01400

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase 1 HAMAP MF_01400

Gene names

Name:	msrB_1 EMBL ACQ68032.1
Synonyms:	msrB1 HAMAP MF_01400
Ordered Locus Names:	HDEF_1400

Organism

Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT) [Complete proteome] [HAMAP]

Taxonomic identifier

572265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › aphid secondary symbionts › Candidatus Hamiltonella

Protein attributes

Sequence length	139 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family. HAMAP MF_01400

Ontologies

Keywords
Ligand	Metal-binding HAMAP MF_01400 Zinc HAMAP MF_01400
Molecular function	Oxidoreductase SAAS SAAS002579 HAMAP MF_01400
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	120	1	Nucleophile By similarity HAMAP MF_01400
	Metal binding	48	1	Zinc By similarity HAMAP MF_01400
	Metal binding	51	1	Zinc By similarity HAMAP MF_01400
	Metal binding	97	1	Zinc By similarity HAMAP MF_01400
	Metal binding	100	1	Zinc By similarity HAMAP MF_01400

Sequences

	Sequence		Length	Mass (Da)
	C4K639 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: 68E3D0152715DF31	FASTA	139	15,698
	10 20 30 40 50 60 MYSLHSLRVE MKIKKLNKIQ NDVTQQSGTE PPFSAKLLNN KKEGIYSCLC CSTPLFSSDN 70 80 90 100 110 120 KFDSECGWPS FNQTIHDQVI KYNHDFSHGM KRIEVRCAHC DAHLGHVFPD GQKPTGQRYC 130 INSAALSFTD KKSGEIIEG

References

[1]	"Hamiltonella defensa, genome evolution of protective bacterial endosymbiont from pathogenic ancestors." Degnan P.H., Yu Y., Sisneros N., Wing R.A., Moran N.A. Proc. Natl. Acad. Sci. U.S.A. 106:9063-9068(2009) [PubMed: 19451630] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001277 Genomic DNA. Translation: ACQ68032.1.
RefSeq	YP_002924180.1. NC_012751.1.
3D structure databases
ProteinModelPortal	C4K639.
ModBase	Search...
Protein-protein interaction databases
STRING	C4K639.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7951000.
GenomeReviews	Gene locus HDEF_1400 in contig CP001277_GR.
KEGG	hde:HDEF_1400.
PATRIC	31974253. VBICanHam112931_1395.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	FTDGPVD.
ProtClustDB	CLSK2508876.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C4K639_HAMD5

Accession

Primary (citable) accession number: C4K639

Entry history

Integrated into UniProtKB/TrEMBL:	July 7, 2009
Last sequence update:	July 7, 2009
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)