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C4K191 (C4K191_RICPU) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00817
EC=1.7.1.13 HAMAP MF_00817
Alternative name(s):
7-cyano-7-carbaguanine reductase HAMAP MF_00817
NADPH-dependent nitrile oxidoreductase HAMAP MF_00817
PreQ(0) reductase HAMAP MF_00817
Gene names
Name:queF HAMAP MF_00817 EMBL ACR47342.1
Ordered Locus Names:RPR_02605
OrganismRickettsia peacockii (strain Rustic) [Complete proteome] [HAMAP]
Taxonomic identifier562019 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group

Protein attributes

Sequence length273 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. HAMAP MF_00817 SAAS SAAS016428

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. HAMAP MF_00817 SAAS SAAS016428

Pathway

tRNA modification; tRNA-queuosine biosynthesis. HAMAP MF_00817 SAAS SAAS016428

Subcellular location

Cytoplasm By similarity HAMAP MF_00817 SAAS SAAS016428.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily. HAMAP MF_00817

Sequences

Sequence LengthMass (Da)Tools
C4K191 [UniParc].

Last modified July 7, 2009. Version 1.
Checksum: BCA8B3B350CA23D4

FASTA27331,222
        10         20         30         40         50         60 
MPLSTSLLGK KSTYKDSYDV TLLFKIPRIN NRNELGINSN NLPFYGVDVW NTYELSCLNK 

        70         80         90        100        110        120 
NGKPWVGVGT FYIPTDSENI VESKSFKLYL NSFNNFVVES VKELERIILQ DLSNVTHAKV 

       130        140        150        160        170        180 
TGRIFPINTK VEFGVPSGKN IDDLDIVCNN YGAPDNSLIE YEDVLVEEEI NSNLLKSNCL 

       190        200        210        220        230        240 
VTSQPDWGTI VIKYKGKKLK YDSFLKYLIS FRNCNEFAEQ CAERIFTDIK NAISPDFLSI 

       250        260        270 
YIVYARRGGI DICPYRSTDK SYTLPSDKRF IRQ

« Hide

References

[1]"Complete genome sequence of Rickettsia peacockii, strain Rustic."
Felsheim R.F., Kurtti T.J., Munderloh U.G.
Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001227 Genomic DNA. Translation: ACR47342.1.
RefSeqYP_002916390.1. NC_012730.1.

3D structure databases

ProteinModelPortalC4K191.
ModBaseSearch...

Protein-protein interaction databases

STRINGC4K191.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7942826.
GenomeReviewsGene locus RPR_02605 in contig CP001227_GR.
KEGGrpk:RPR_02605.
PATRIC17898571. VBIRicPea48268_0509.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMACVERIFC.
ProtClustDBPRK11792.

Family and domain databases

HAMAPMF_00817. QueF_type2.
[Tree]
InterProIPR016428. CN_OxRdtase_NADPH-dep_YqcD.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
KOK06879.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
PIRSFPIRSF004750. Nitrile_oxidored_YqcD_prd. 1 hit.
TIGRFAMsTIGR03138. QueF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC4K191_RICPU
AccessionPrimary (citable) accession number: C4K191
Entry history
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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