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Protein

DNA ligase

Gene

UREG_07481

Organism
Uncinocarpus reesii (strain UAMH 1704)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:UREG_07481Imported
OrganismiUncinocarpus reesii (strain UAMH 1704)Imported
Taxonomic identifieri336963 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesOnygenaceaeUncinocarpus
ProteomesiUP000002058: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliC4JZ80.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiC4JZ80.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C4JZ80-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPNPASKRKR DDASDSKSFR SIDSFFRSPK KRQPQVDICT PAPPGNQALT
60 70 80 90 100
DEELARKLQA EWDRDAAPSR DGPHTEANTQ AALLPQSVER KGDLQIADSP
110 120 130 140 150
PKTSGVVPEK KTKGVLSLQT SATTEDTISM SLPLDQPPLS FKPSTYIEQL
160 170 180 190 200
REFWGLEGGR ASYSILARAF SLVNSTQSRI KIVDILVNLL RILIEGNPDS
210 220 230 240 250
LLPAVWLATN AFAPPYVPLE LGLGGSAISK ALKKAYGLDN LGLKSLYDKH
260 270 280 290 300
GDAGDVAYEA KKKQSFTLRR PKPLSIKGVY DSLTGIANSK GTGSQENKQR
310 320 330 340 350
IVEQLLRDAR GAEESRYIVR TLVQHLRIGA VRTTMLIALA RAFLYSRPPS
360 370 380 390 400
ATFEVYLQPD LMNLKKDELS NLYARAEEIV KASYARHPNY NDLIPCLLET
410 420 430 440 450
GISKAVLAKC GLSLHIPLLP MLGSITRDLT EMLTKLQGKK FSCEYKYDGQ
460 470 480 490 500
RAQVHCDTAG KVSLFSRHLE FMTDKYPDLV SLVPQIRGDG VSSFILEGEV
510 520 530 540 550
VAVDQESGDL LPFQTLSNRA KKNVEMSNIK INVCLFAFDL MYLNGEPLLE
560 570 580 590 600
RSFRERRELL RSLFVEIPKR FSWVKSIDAT STDSDMILNF FREATKEKCE
610 620 630 640 650
GIMVKVLDTD VEAVETVGLG SAIKESSNIA KEKQKGTRKR ALLSTYEPDK
660 670 680 690 700
RLESWLKVKK DYSTASDTLD LIPIAGWHGQ GRKAKWWSPI LLAVRNPETG
710 720 730 740 750
SLEAVTKCMS GFTDKFYQEN KEKYAEHGDN VISRPSYVDY RNEPEVWFEP
760 770 780 790 800
QEVWEVAFAD ITLSPTYTAA IGLVSEERGL SLRFPRFLRV REDKTIEEAS
810 820
TSAYLAELWR KQSARLQIEG VDSMQEEP
Length:828
Mass (Da):92,694
Last modified:July 7, 2009 - v1
Checksum:i6FD6603C0F7026C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476619 Genomic DNA. Translation: EEP82616.1.
RefSeqiXP_002582708.1. XM_002582662.1.

Genome annotation databases

GeneIDi8439949.
KEGGiure:UREG_07481.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476619 Genomic DNA. Translation: EEP82616.1.
RefSeqiXP_002582708.1. XM_002582662.1.

3D structure databases

ProteinModelPortaliC4JZ80.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8439949.
KEGGiure:UREG_07481.

Phylogenomic databases

InParanoidiC4JZ80.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UAMH 1704Imported.

Entry informationi

Entry nameiC4JZ80_UNCRE
AccessioniPrimary (citable) accession number: C4JZ80
Entry historyi
Integrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: January 7, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.