ID   C4JSG4_UNCRE            Unreviewed;      1041 AA.
AC   C4JSG4;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   RecName: Full=Probable E3 ubiquitin ligase complex SCF subunit sconB {ECO:0000256|ARBA:ARBA00015819};
DE   AltName: Full=Sulfur controller B {ECO:0000256|ARBA:ARBA00032113};
DE   AltName: Full=Sulfur metabolite repression control protein B {ECO:0000256|ARBA:ARBA00030034};
GN   ORFNames=UREG_05403 {ECO:0000313|EMBL:EEP80561.1};
OS   Uncinocarpus reesii (strain UAMH 1704).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX   NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP80561.1, ECO:0000313|Proteomes:UP000002058};
RN   [1] {ECO:0000313|Proteomes:UP000002058}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: Component of the SCF(sconB) E3 ubiquitin ligase complex
CC       involved in the regulation of sulfur metabolite repression, probably by
CC       mediating the inactivation or degradation of the metR transcription
CC       factor. {ECO:0000256|ARBA:ARBA00002730}.
CC   -!- PATHWAY: Protein modification. {ECO:0000256|ARBA:ARBA00043952}.
CC   -!- SUBUNIT: Component of the SCF(sconB) E3 ubiquitin ligase complex.
CC       {ECO:0000256|ARBA:ARBA00011725}.
CC   -!- SIMILARITY: Belongs to the WD repeat MET30/SCONB/SCON-2 family.
CC       {ECO:0000256|ARBA:ARBA00007968}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH476617; EEP80561.1; -; Genomic_DNA.
DR   RefSeq; XP_002584714.1; XM_002584668.1.
DR   AlphaFoldDB; C4JSG4; -.
DR   STRING; 336963.C4JSG4; -.
DR   GeneID; 8438052; -.
DR   KEGG; ure:UREG_05403; -.
DR   VEuPathDB; FungiDB:UREG_05403; -.
DR   eggNOG; KOG0274; Eukaryota.
DR   HOGENOM; CLU_000288_103_3_1; -.
DR   InParanoid; C4JSG4; -.
DR   OMA; TMCRAAQ; -.
DR   OrthoDB; 587035at2759; -.
DR   Proteomes; UP000002058; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0043170; P:macromolecule metabolic process; IEA:UniProt.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR   GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR   CDD; cd22147; F-box_SpPof1-like; 1.
DR   CDD; cd00200; WD40; 1.
DR   Gene3D; 1.20.1280.50; -; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR19849; PHOSPHOLIPASE A-2-ACTIVATING PROTEIN; 1.
DR   PANTHER; PTHR19849:SF3; PROTEIN WITH WD-40 REPEAT DOMAIN; 1.
DR   Pfam; PF12937; F-box-like; 1.
DR   Pfam; PF00400; WD40; 6.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00256; FBOX; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF81383; F-box domain; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50181; FBOX; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 6.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000313|EMBL:EEP80561.1};
KW   Cell division {ECO:0000313|EMBL:EEP80561.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002058};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   DOMAIN          445..492
FT                   /note="F-box"
FT                   /evidence="ECO:0000259|PROSITE:PS50181"
FT   REPEAT          695..734
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          765..784
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          809..848
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          849..890
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          891..930
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          931..969
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          149..221
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          259..304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          338..363
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          532..581
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..30
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        169..204
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        279..299
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        532..552
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1041 AA;  115591 MW;  A3816FF9A3FDDDFD CRC64;
     MASNDAARHT MKTPERSEYQ VNSSSFDRAS CNETSEDDSR SEPTVGQFSF APATQTTIVT
     TTTTTTTSFP PLVMKAPRPL DGLDPKHYPL ASSETPLSLR DIKFNLNGQS IVFHESDHAA
     STLTEQQEAL SASDGVIRSV AIANPLPRSD SIYSRLPRHG HRSLNNLNTK RRRVSPVPTA
     ESSQDPNPSR SFVPEPSTSR HPRRTCSSAT KHPWHFPDVG LATPETESAN FVLDSEMNQP
     KKASKLGLFV ERQYESPCIS GENRRGSLDD GEQTSPLLER RSGLPSDTLM SSLSSSSDIG
     PRPARRLRPL VSRLVAVDGN SAENLPLPSP RLSPIAAANA SQQEVSFDST EDQTTDTDSN
     NDLVQNETIS LYDVARKSNS REGEARNVID YASSSLSLMD MPVMLSYFES IPDELKSYVM
     YQLLKRCPKQ TLHVVADVVN PALKCDFLAL LPFELSLNIV KFLDVQSMCR ASQVSKKWRH
     IINSDEKTWK AHFDAAGFNL PEAELQQAIE EGWAWQYSGD FEQDLRLCSA SDSESLPQTS
     HSRETPTLND AISGGSRKLK RKAVSIPPGR GSAKKQLLKD DSPEQHEIAN WIHNLKIAEG
     PYAAANAAAL ALPYPEIGLP SLRSLHLYKS LYQRHHSIRK MWMDRNAKPL HIAFRAHDRH
     VVTCLQFDTD KILTGSDDTN IHVYDTKTGA IKSTLEGHEG GVWALEYHGN TLVSGSTDRS
     VRVWDIEKAE CTQTFQGHTS TVRCLKILLP TEIGRKPDGT IETMPKEPLI ITGSRDSSLR
     VWRLPQPGDP KYFQAGPEDD NCPYFIRALN GHTHSVRAIA AHGDTLVSGS YDCTVRVWKI
     STGEVVHRLE GHSLKVYSVV LDHQRNRCIS GSMDHFVKIW SLETGSLLYN LEGHALLVGL
     LDLQADKLVS AAADSTLRIW DPETGHCKNI LTAHTGAITC FEHDEQKIIS GSDRTLKMWN
     IKTGECFKDL LTDLSCVWQV RFNERRCVAA VQRNGRTYIE VLDFGASRDR VPADRLGRRI
     VVDSHGKEIP EANERAGDGN E
//