C4JRH4 (C4JRH4_UNCRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

ORF Names:

UREG_05063 EMBL EEP80221.1

Organism

Uncinocarpus reesii (strain UAMH 1704) [Complete proteome] EMBL EEP80221.1

Taxonomic identifier

336963 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Onygenales › Onygenaceae › Uncinocarpus › Uncinocarpus reesii

Protein attributes

Sequence length	1009 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C4JRH4 [UniParc]. Last modified July 7, 2009. Version 1. Checksum: 2049706A9DECD153	FASTA	1,009	115,751
	10 20 30 40 50 60 MDGLNGPKGE TEQELDEKYP NRPRNHHPTL PFHDLFLDLF NPLNENKKRP AGSTVARRKL 70 80 90 100 110 120 GPHGGQQTLS PQELRRDIIQ RFISKWRNEV GDDIYPAFRL IIPEKDRDRA MYGLKEKTIG 130 140 150 160 170 180 KLLVKIMKID KNSEDGFNLL NWKLPGQSMA SRMAGDFAGR CYEVISKRPM RTEVGNMTVQ 190 200 210 220 230 240 EVNEKLDLLA AANKEDEQLP ILEDFYRKMN PEELLWLIRI ILRQMKVGAT ERTFFEIWHP 250 260 270 280 290 300 DAETLFSISS SLRRVCWELY NPNVRLEDEE TGVTLMQCFQ PQLAQFQMHS FQRMIEKMRL 310 320 330 340 350 360 SPEDPSFWIE EKMDGERMQL HMMSDDSITG GKRFKFWSRK AKDYTYLYGN GFYDENGALT 370 380 390 400 410 420 RHLKDAFADG VQNIILDGEM ITWDPEQDAP VPFGTLKTAA LSEQRNPFSA TGQRPLFRAF 430 440 450 460 470 480 DILYLNDKAL TRYTLRDRRK ALEASIKPVH RRFEIHTYEV GYSAAHIEPQ LRKVVAEASE 490 500 510 520 530 540 GLVLKNPDSP YRLNERHDDW MKVKPEYMTE FGESLDCVVI GGYYGSGKRG GALATFLCGL 550 560 570 580 590 600 RVDEAQIRQG ANPMKCYSFC KVGGGFTAAD YANVRHHTDS KWKDWDPKKP PTEFIELAGG 610 620 630 640 650 660 DAQYERPDVW IRPDESVVLC VKASSVTPSD QFRLGLTVRF PRFKRLRMDK TWESALSIQE 670 680 690 700 710 720 FMDLKSNAER EQKEKEFKID NSRKRKPKRT TKKPLTIAGY DENKKAEFDV SDQIFTSKSD 730 740 750 760 770 780 SLVVMTDALE PEKKSKLELE KLIKANGGKI YQTNTAASNT ICIAERRTVK VASIQKAAKE 790 800 810 820 830 840 NIVRPSWLLD CIKQNEADLG LPDLLLPLEP RHMYFTVKGQ EQEISSNVDQ YSDSYVRDTT 850 860 870 880 890 900 TKELTKLLAS MPAISNLSAS RISKIEDQMQ SRHEQEGTFH DLPGWLFKNQ VLYFSQSRSS 910 920 930 940 950 960 SDSKVSSSRL ASNIARFAGA SLVSKPDDKR VTHIILDKDS RSADVSALRS SISKRVGAGR 970 980 990 1000 IPHIVTVEWI NESWKAKTLL DEEQLLKGVH FEFRKVCIDA FYRSHISVS

References

[1]

"Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives." Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N. , Orbach M.J., Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W. Genome Res. 19:1722-1731(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: UAMH 1704.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH476617 Genomic DNA. Translation: EEP80221.1.
RefSeq	XP_002584374.1. XM_002584328.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8443373.
KEGG	ure:UREG_05063.
Phylogenomic databases
KO	K10777.
OrthoDB	EOG41K2MD.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
InterPro	IPR001357. BRCT_dom. IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF00533. BRCT. 1 hit. PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SMART	SM00292. BRCT. 2 hits. [Graphical view]
SUPFAM	SSF52113. BRCT. 2 hits. SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS50172. BRCT. 2 hits. PS00697. DNA_LIGASE_A1. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C4JRH4_UNCRE

Accession

Primary (citable) accession number: C4JRH4

Entry history

Integrated into UniProtKB/TrEMBL:	July 7, 2009
Last sequence update:	July 7, 2009
Last modified:	March 6, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)