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Protein

DNA ligase

Gene

UREG_05063

Organism
Uncinocarpus reesii (strain UAMH 1704)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotation
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:UREG_05063Imported
OrganismiUncinocarpus reesii (strain UAMH 1704)Imported
Taxonomic identifieri336963 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesOnygenaceaeUncinocarpus
Proteomesi
  • UP000002058 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi336963.XP_002584374.1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini417 – 542DNA_LIGASE_A3InterPro annotationAdd BLAST126
Domaini723 – 796BRCTInterPro annotationAdd BLAST74
Domaini886 – 987BRCTInterPro annotationAdd BLAST102

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0966. Eukaryota.
COG1793. LUCA.
InParanoidiC4JRH4.
KOiK10777.
OrthoDBiEOG092C18KW.

Family and domain databases

CDDicd00027. BRCT. 2 hits.
Gene3Di1.10.3260.10. 1 hit.
3.40.50.10190. 2 hits.
InterProiView protein in InterPro
IPR001357. BRCT_dom.
IPR036420. BRCT_dom_sf.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR036599. DNA_ligase_N_sf.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiView protein in Pfam
PF16589. BRCT_2. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
SMARTiView protein in SMART
SM00292. BRCT. 2 hits.
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiView protein in PROSITE
PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.

Sequencei

Sequence statusi: Complete.

C4JRH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGLNGPKGE TEQELDEKYP NRPRNHHPTL PFHDLFLDLF NPLNENKKRP
60 70 80 90 100
AGSTVARRKL GPHGGQQTLS PQELRRDIIQ RFISKWRNEV GDDIYPAFRL
110 120 130 140 150
IIPEKDRDRA MYGLKEKTIG KLLVKIMKID KNSEDGFNLL NWKLPGQSMA
160 170 180 190 200
SRMAGDFAGR CYEVISKRPM RTEVGNMTVQ EVNEKLDLLA AANKEDEQLP
210 220 230 240 250
ILEDFYRKMN PEELLWLIRI ILRQMKVGAT ERTFFEIWHP DAETLFSISS
260 270 280 290 300
SLRRVCWELY NPNVRLEDEE TGVTLMQCFQ PQLAQFQMHS FQRMIEKMRL
310 320 330 340 350
SPEDPSFWIE EKMDGERMQL HMMSDDSITG GKRFKFWSRK AKDYTYLYGN
360 370 380 390 400
GFYDENGALT RHLKDAFADG VQNIILDGEM ITWDPEQDAP VPFGTLKTAA
410 420 430 440 450
LSEQRNPFSA TGQRPLFRAF DILYLNDKAL TRYTLRDRRK ALEASIKPVH
460 470 480 490 500
RRFEIHTYEV GYSAAHIEPQ LRKVVAEASE GLVLKNPDSP YRLNERHDDW
510 520 530 540 550
MKVKPEYMTE FGESLDCVVI GGYYGSGKRG GALATFLCGL RVDEAQIRQG
560 570 580 590 600
ANPMKCYSFC KVGGGFTAAD YANVRHHTDS KWKDWDPKKP PTEFIELAGG
610 620 630 640 650
DAQYERPDVW IRPDESVVLC VKASSVTPSD QFRLGLTVRF PRFKRLRMDK
660 670 680 690 700
TWESALSIQE FMDLKSNAER EQKEKEFKID NSRKRKPKRT TKKPLTIAGY
710 720 730 740 750
DENKKAEFDV SDQIFTSKSD SLVVMTDALE PEKKSKLELE KLIKANGGKI
760 770 780 790 800
YQTNTAASNT ICIAERRTVK VASIQKAAKE NIVRPSWLLD CIKQNEADLG
810 820 830 840 850
LPDLLLPLEP RHMYFTVKGQ EQEISSNVDQ YSDSYVRDTT TKELTKLLAS
860 870 880 890 900
MPAISNLSAS RISKIEDQMQ SRHEQEGTFH DLPGWLFKNQ VLYFSQSRSS
910 920 930 940 950
SDSKVSSSRL ASNIARFAGA SLVSKPDDKR VTHIILDKDS RSADVSALRS
960 970 980 990 1000
SISKRVGAGR IPHIVTVEWI NESWKAKTLL DEEQLLKGVH FEFRKVCIDA

FYRSHISVS
Length:1,009
Mass (Da):115,751
Last modified:July 7, 2009 - v1
Checksum:i2049706A9DECD153
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH476617 Genomic DNA. Translation: EEP80221.1.
RefSeqiXP_002584374.1. XM_002584328.1.

Genome annotation databases

EnsemblFungiiEEP80221; EEP80221; UREG_05063.
GeneIDi8443373.
KEGGiure:UREG_05063.

Similar proteinsi

Entry informationi

Entry nameiC4JRH4_UNCRE
AccessioniPrimary (citable) accession number: C4JRH4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: October 25, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported