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Protein
Submitted name:

Mineralocorticoid receptor

Gene

nr3c2

Organism
Oryzias latipes (Japanese rice fish) (Japanese killifish)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi613 – 688Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Mineralocorticoid receptorImported
Gene namesi
Name:nr3c2Imported
OrganismiOryzias latipes (Japanese rice fish) (Japanese killifish)Imported
Taxonomic identifieri8090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeBeloniformesAdrianichthyidaeOryziinaeOryzias
Proteomesi
  • UP000001038 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi8090.ENSORLP00000009438

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini613 – 688Nuclear receptorInterPro annotationAdd BLAST76
Domaini740 – 974NR LBDInterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118887
KOiK08555
OMAiIATPREC
OrthoDBiEOG091G0166
TreeFamiTF106510

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

C4B4D1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAKRYQSFF DGDDTENKWS QVPSDMEYCC NTDDSSLTNS ETLMDMVNVS
60 70 80 90 100
CSAGSPIADS KDNNSNKQEQ PRLQLGRDQP FLLPHFNNSL HGHKQEMDSK
110 120 130 140 150
ELSKTVAESM GLYMNAAREA DFAFSQQGGN TSPGKLHPVS GQPPEEKRCG
160 170 180 190 200
STKSPKLKPF NFQHPIATPR ECPSAAPVSS ASILASSLSC SPKTSSSMSS
210 220 230 240 250
PGGSNNMVSS TTSPSTCFGP QCSAVSSPVS QTSCAATLAN IKRRNSVTCS
260 270 280 290 300
PVESCTVGSP PLTSPLNIMR SPMSSPHSMS SVRSPPSCST TCNIRSSVSS
310 320 330 340 350
PTGGSCTGVP NNCCSVRPSN SSPTTGGTLA VSSPHNPSSG GFSESSPAGG
360 370 380 390 400
LGLVQNDSSS PEVPGLTRDT NFKNFEFPKV EMVGGEVFSV GLDQMGMVKY
410 420 430 440 450
IKNEPESDFR SMCLGSSKCN TSSTPYITQI KSEPNKGEGC MNQQSYDEQS
460 470 480 490 500
PSLDLFPTSD TTYLSLRNNI DEYNLSGILG PPVSSMNGSY EPDMFSSNVL
510 520 530 540 550
SKGVKQESTD GSYFQENNTM PTSAIVGVNS TGHSFHYQIG AQGTMSFTRH
560 570 580 590 600
DVRDQSNPLL NLISPVTALM ESWKSRPGMP HGSFSARGEG YPSQNCIGDN
610 620 630 640 650
MSSSSLRQPS STAKVCLVCG DEASGCHYGV VTCGSCKVFF KRAVEGQHNY
660 670 680 690 700
LCAGRNDCII DKIRRKNCPA CRVRKCLQAG MNLGARKSKK LKLKGVSEDL
710 720 730 740 750
QSSKDGQTAT GGVGGSYLTS EKELNSSAAN ALVPHGPGVV TPFLSPSICS
760 770 780 790 800
VLELIEPEEV YSGYDNTLPD TTDHLLSSLN RLAGKQMVRM VKWAKVLPGF
810 820 830 840 850
RVLPIEDQIT LIQYSWMCLS SFCLSWRSYK HTNGQMLYFA PDLVFNEDRM
860 870 880 890 900
RQSAMYDLCL GMRQVSQEFV RLQLTYDEFL SMKVLLLLST VPKEGLKNQA
910 920 930 940 950
AFEEMRVNYI KELRRSVGKA TNNSGQTWQR FFQLTKLLDA MHDLVGNLLD
960 970 980 990
FCFYTFRESQ ALKVEFPEML VEIISDQIPK VESGLTHTIY FHKK
Length:994
Mass (Da):108,097
Last modified:July 7, 2009 - v1
Checksum:i608DBB96F97616CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BAAF04076780 Genomic DNA No translation available.
BAAF04076781 Genomic DNA No translation available.
BAAF04076782 Genomic DNA No translation available.
BAAF04076783 Genomic DNA No translation available.
BAAF04076784 Genomic DNA No translation available.
BAAF04076785 Genomic DNA No translation available.
BAAF04076786 Genomic DNA No translation available.
BAAF04076787 Genomic DNA No translation available.
BAAF04076788 Genomic DNA No translation available.
BAAF04076789 Genomic DNA No translation available.
AB284184 mRNA Translation: BAH59525.1
RefSeqiNP_001156601.1, NM_001163129.1
XP_011474612.1, XM_011476310.1
UniGeneiOla.27481

Genome annotation databases

EnsembliENSORLT00000009439; ENSORLP00000009438; ENSORLG00000007530
GeneIDi100302443
KEGGiola:100302443

Similar proteinsi

Entry informationi

Entry nameiC4B4D1_ORYLA
AccessioniPrimary (citable) accession number: C4B4D1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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