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Protein
Submitted name:

Mineralocorticoid receptor

Gene

nr3c2

Organism
Oryzias latipes (Japanese rice fish) (Japanese killifish)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi613 – 688Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Mineralocorticoid receptorImported
Gene namesi
Name:nr3c2Imported
OrganismiOryzias latipes (Japanese rice fish) (Japanese killifish)
Taxonomic identifieri8090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeBeloniformesAdrianichthyidaeOryziinaeOryzias
Proteomesi
  • UP000001038 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi8090.ENSORLP00000009438.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini613 – 688Nuclear receptorInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
GeneTreeiENSGT00760000118887.
OMAiTHTLYFH.
OrthoDBiEOG091G0166.
TreeFamiTF106510.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR035500. NHR_like_dom_sf.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

C4B4D1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAKRYQSFF DGDDTENKWS QVPSDMEYCC NTDDSSLTNS ETLMDMVNVS
60 70 80 90 100
CSAGSPIADS KDNNSNKQEQ PRLQLGRDQP FLLPHFNNSL HGHKQEMDSK
110 120 130 140 150
ELSKTVAESM GLYMNAAREA DFAFSQQGGN TSPGKLHPVS GQPPEEKRCG
160 170 180 190 200
STKSPKLKPF NFQHPIATPR ECPSAAPVSS ASILASSLSC SPKTSSSMSS
210 220 230 240 250
PGGSNNMVSS TTSPSTCFGP QCSAVSSPVS QTSCAATLAN IKRRNSVTCS
260 270 280 290 300
PVESCTVGSP PLTSPLNIMR SPMSSPHSMS SVRSPPSCST TCNIRSSVSS
310 320 330 340 350
PTGGSCTGVP NNCCSVRPSN SSPTTGGTLA VSSPHNPSSG GFSESSPAGG
360 370 380 390 400
LGLVQNDSSS PEVPGLTRDT NFKNFEFPKV EMVGGEVFSV GLDQMGMVKY
410 420 430 440 450
IKNEPESDFR SMCLGSSKCN TSSTPYITQI KSEPNKGEGC MNQQSYDEQS
460 470 480 490 500
PSLDLFPTSD TTYLSLRNNI DEYNLSGILG PPVSSMNGSY EPDMFSSNVL
510 520 530 540 550
SKGVKQESTD GSYFQENNTM PTSAIVGVNS TGHSFHYQIG AQGTMSFTRH
560 570 580 590 600
DVRDQSNPLL NLISPVTALM ESWKSRPGMP HGSFSARGEG YPSQNCIGDN
610 620 630 640 650
MSSSSLRQPS STAKVCLVCG DEASGCHYGV VTCGSCKVFF KRAVEGQHNY
660 670 680 690 700
LCAGRNDCII DKIRRKNCPA CRVRKCLQAG MNLGARKSKK LKLKGVSEDL
710 720 730 740 750
QSSKDGQTAT GGVGGSYLTS EKELNSSAAN ALVPHGPGVV TPFLSPSICS
760 770 780 790 800
VLELIEPEEV YSGYDNTLPD TTDHLLSSLN RLAGKQMVRM VKWAKVLPGF
810 820 830 840 850
RVLPIEDQIT LIQYSWMCLS SFCLSWRSYK HTNGQMLYFA PDLVFNEDRM
860 870 880 890 900
RQSAMYDLCL GMRQVSQEFV RLQLTYDEFL SMKVLLLLST VPKEGLKNQA
910 920 930 940 950
AFEEMRVNYI KELRRSVGKA TNNSGQTWQR FFQLTKLLDA MHDLVGNLLD
960 970 980 990
FCFYTFRESQ ALKVEFPEML VEIISDQIPK VESGLTHTIY FHKK
Length:994
Mass (Da):108,097
Last modified:July 7, 2009 - v1
Checksum:i608DBB96F97616CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BAAF04076780 Genomic DNA. No translation available.
BAAF04076781 Genomic DNA. No translation available.
BAAF04076782 Genomic DNA. No translation available.
BAAF04076783 Genomic DNA. No translation available.
BAAF04076784 Genomic DNA. No translation available.
BAAF04076785 Genomic DNA. No translation available.
BAAF04076786 Genomic DNA. No translation available.
BAAF04076787 Genomic DNA. No translation available.
BAAF04076788 Genomic DNA. No translation available.
BAAF04076789 Genomic DNA. No translation available.
AB284184 mRNA. Translation: BAH59525.1.
RefSeqiNP_001156601.1. NM_001163129.1.
XP_011474612.1. XM_011476310.1.
UniGeneiOla.27481.

Genome annotation databases

EnsembliENSORLT00000009439; ENSORLP00000009438; ENSORLG00000007530.
GeneIDi100302443.

Similar proteinsi

Entry informationi

Entry nameiC4B4D1_ORYLA
AccessioniPrimary (citable) accession number: C4B4D1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 7, 2009
Last sequence update: July 7, 2009
Last modified: November 22, 2017
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported