C4A0A6 (C4A0A6_BRAFL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ubiquitin carboxyl-terminal hydrolase RuleBase RU004435
EC=3.4.19.12 RuleBase RU004435

Gene names

Name:	Rab23b EMBL EEN41765.1
ORF Names:	BRAFLDRAFT_232629 EMBL EEN41765.1

Organism

Branchiostoma floridae (Florida lancelet) (Amphioxus) [Reference proteome] EMBL EEN41765.1

Taxonomic identifier

7739 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Cephalochordata › Branchiostomidae › Branchiostoma

Protein attributes

Sequence length	488 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal). RuleBase RU004435
Sequence similarities	Belongs to the peptidase C19 family. RuleBase RU004434

Ontologies

Keywords
Biological process	Ubl conjugation pathway RuleBase RU004434
Molecular function	Hydrolase Protease Thiol protease RuleBase RU004434
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ubiquitin-dependent protein catabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	cysteine-type peptidase activity Inferred from electronic annotation. Source: UniProtKB-KW ubiquitin thiolesterase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C4A0A6 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 19E723121C8AF6B6	FASTA	488	55,305
	10 20 30 40 50 60 MEIPLSSSLS VKVKWQKQKF DDIDLDTDEP PEVFKAQLFA LSGVQPDRQK VMLKGSTLKD 70 80 90 100 110 120 EGWETLKGLK NGVTLMMMGT ADALPQEPVE RPKFVEDMSE AELNKAMELP AGMTNLGNTC 130 140 150 160 170 180 YMNATVQCLR NVPELKEVLK RFQGGLSSSG DLTAAQSITA AFRDLNGSMD SGSATITPIV 190 200 210 220 230 240 LLQVLHMAFP HFAEKAEQGG FRQQDANECW VEMVRMLQQK LPPVERVGTE VSVEKVKRFM 250 260 270 280 290 300 DQFFSGELVS TMKCVESEEE EEKTSSETFF QLSCFISQGT KVFFPVMEKD RLEEIITKHS 310 320 330 340 350 360 PSLGRDAQYK KTSKVRRLPA YLTIQMVRFF YKEKENVNAK ILKDVKFPMS LDLFDMCTTE 370 380 390 400 410 420 LQTKLEPVRS KFKEEEDRKA KEAGKTVVPN KDVQYETYEF PDDIGSNNSG YYTLQAVLTH 430 440 450 460 470 480 QGRSSSSGHY VAWVRRDADW IKCDDDKVYA VTEEDVLKLS GGGDWHCAYV LLYGPRRLEV PPPEKMEI

References

[1]

"The amphioxus genome and the evolution of the chordate karyotype." US DOE Joint Genome Institute (JGI-PGF) Putnam N.H., Butts T., Ferrier D.E., Furlong R.F., Hellsten U., Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.K., Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J., Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J. , Kapitonov V.V., Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A., Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T., Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W., Satoh N., Rokhsar D.S. Nature 453:1064-1071(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S238N-H82 EMBL EEN41765.1. Tissue: Testes EMBL EEN41765.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GG666796 Genomic DNA. Translation: EEN41765.1.
RefSeq	XP_002585754.1. XM_002585708.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	7739.JGI232629.
Protein family/group databases
MEROPS	C19.015.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7249473.
KEGG	bfo:BRAFLDRAFT_232629.
Organism-specific databases
CTD	7249473.
Phylogenomic databases
eggNOG	NOG286607.
KO	K11843.
OMA	YGPRRIE.
Family and domain databases
InterPro	IPR018200. Pept_C19ubi-hydrolase_C_CS. IPR001394. Peptidase_C19. IPR000626. Ubiquitin. IPR019954. Ubiquitin_CS. IPR019955. Ubiquitin_supergroup. [Graphical view]
Pfam	PF00443. UCH. 1 hit. [Graphical view]
SMART	SM00213. UBQ. 1 hit. [Graphical view]
PROSITE	PS00299. UBIQUITIN_1. 1 hit. PS50053. UBIQUITIN_2. 1 hit. PS00972. UCH_2_1. 1 hit. PS00973. UCH_2_2. 1 hit. PS50235. UCH_2_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C4A0A6_BRAFL

Accession

Primary (citable) accession number: C4A0A6

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	April 3, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)