C3ZA55 (C3ZA55_BRAFL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histone deacetylase PIRNR PIRNR037913
EC=3.5.1.98 PIRNR PIRNR037913

Gene names

ORF Names:

BRAFLDRAFT_217516 EMBL EEN50643.1

Organism

Branchiostoma floridae (Florida lancelet) (Amphioxus)

Taxonomic identifier

7739 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Cephalochordata › Branchiostomidae › Branchiostoma

Protein attributes

Sequence length	462 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone. PIRNR PIRNR037913
Subcellular location	Nucleus By similarity PIRNR PIRNR037913.
Sequence similarities	Belongs to the histone deacetylase family. HD Type 1 subfamily. PIRNR PIRNR037913

Ontologies

Keywords
Biological process	Transcription Transcription regulation PIRNR PIRNR037913
Cellular component	Nucleus PIRNR PIRNR037913
Molecular function	Chromatin regulator PIRNR PIRNR037913 Hydrolase PIRNR PIRNR037913 SAAS SAAS000286
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	NAD-dependent histone deacetylase activity (H3-K14 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H3-K9 specific) Inferred from electronic annotation. Source: EC NAD-dependent histone deacetylase activity (H4-K16 specific) Inferred from electronic annotation. Source: EC histone deacetylase activity (H3-K16 specific) Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3ZA55 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 99830143DA10672B	FASTA	462	53,115
	10 20 30 40 50 60 MAYTQPAGKR KICYYYDGDI GNYYYGQGHP MKPHRIRMTH NLLLNYGLYR KMEIYRPHKA 70 80 90 100 110 120 SFEEMTKYHS DDYIKFLRSI RPDNMSEYSK QMQRFNVGED CPVFDGLYEF CQLSTGGSVA 130 140 150 160 170 180 GAVKLNKQQA DIAVNWAGGL HHAKKSEASG FCYVNDIVLA ILELLKYHQR VLYVDIDIHH 190 200 210 220 230 240 GDGVEEAFYT TDRVMTVSFH KYGEYFPGTG DLRDIGAGKG KYYAVNFPLR DGIDDEAYEH 250 260 270 280 290 300 IFEPVMSKVM EMYQPSAIVL QCGADSLSGD RLGCFNLSLK GHGKCVEFMK KFNIPILMLG 310 320 330 340 350 360 GGGYTIRNVA RCWTFETSIA LGCDVANELP YNDYFEYYGP DFKLHISPSN MTNQNTPEYL 370 380 390 400 410 420 EKIKQRLFEN LRMLPHAPGV QMQAIPEDAI DQESEDNEEE DPDKRVSIRA QDKRITCDEE 430 440 450 460 FSDSEDEGEG GRRDHHSHKK RKRLQREEDK KEEDKKTGLC CN

References

[1]

"The amphioxus genome and the evolution of the chordate karyotype." US DOE Joint Genome Institute (JGI-PGF) Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U., Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K., Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J., Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J. , Kapitonov V.V., Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A., Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T., Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H., Satoh N., Rokhsar D.S. Nature 453:1064-1071(2008) [PubMed: 18563158] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S238N-H82 EMBL EEN50643.1. Tissue: Testes EMBL EEN50643.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GG666601 Genomic DNA. Translation: EEN50643.1.
RefSeq	XP_002594632.1. XM_002594586.1.
UniGene	Bfl.18395.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C3ZA55.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7211276.
KEGG	bfo:BRAFLDRAFT_217516.
Phylogenomic databases
OMA	IPEDAPH.
PhylomeDB	C3ZA55.
Family and domain databases
InterPro	IPR000286. His_deacetylse. IPR003084. His_deacetylse_1. IPR023801. His_deacetylse_dom. [Graphical view]
Gene3D	G3DSA:3.40.800.20. His_deacetylse. 1 hit.
KO	K06067.
PANTHER	PTHR10625. His_deacetylse. 1 hit.
Pfam	PF00850. Hist_deacetyl. 1 hit. [Graphical view]
PIRSF	PIRSF037913. His_deacetylse_1. 1 hit.
PRINTS	PR01270. HDASUPER. PR01271. HISDACETLASE.
ProtoNet	Search...

Entry information

Entry name

C3ZA55_BRAFL

Accession

Primary (citable) accession number: C3ZA55

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)