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Protein

DNA ligase

Gene

BRAFLDRAFT_69217

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotation
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:BRAFLDRAFT_69217Imported
OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)Imported
Taxonomic identifieri7739 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma
Proteomesi
  • UP000001554 Componenti: Partially assembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi7739.JGI69217

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini680 – 816DNA_LIGASE_A3InterPro annotationAdd BLAST137

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili164 – 193Sequence analysisAdd BLAST30
Coiled coili265 – 289Sequence analysisAdd BLAST25

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0967 Eukaryota
COG1793 LUCA
InParanoidiC3Z7P4
KOiK10747
OMAiRVACWEK

Family and domain databases

Gene3Di1.10.3260.10, 2 hits
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 2 hits
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

C3Z7P4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQRSISSFF APRAKTPKQD TAATGHKSPL KTKNGSPPAF APGDDSPVKS
60 70 80 90 100
LPRKKKARRI IDSDDDDEDE EENVAMEIEP SKSADEQKEA KDVEKTPKEV
110 120 130 140 150
EKVKDESEDV PSPKMPRVTY NGPNLQSPGG IPKRKTARKQ LPTPKRKLVE
160 170 180 190 200
IKSPKSNGHT SPTAEEEESS AKKVKTEKKE EKEEKTEEKM EEDSPDEEVK
210 220 230 240 250
EKVKDEEEVV QQNKKKKSPK PKKEKQSPKS VDKKKKIKEE PGEKAKESAG
260 270 280 290 300
PSEDSMDSLF AAVIRKAGEA TAEEEKEETE EKKEKSTEDL KSPSDKKAVK
310 320 330 340 350
KEEDSSKKSS SGISSFFSPK RSSQPTDESS EKKPSPKPAA KPMAAFFKPK
360 370 380 390 400
QEADKTVPYL ALAKTFEAIE EVRARLKITE ILCNFFRSVI ALTPDDLVQC
410 420 430 440 450
VYLCLNKVGP AYEGLELGIG ETVLMKAIAE ATGRKMAQIK TDAQEKGDLG
460 470 480 490 500
IVAEVMTKKI NFIKGMFVAC RQSEARYLIR SLGGKLRIGL AEQSVLTALA
510 520 530 540 550
HAATLTPAGK DVLDAGKGKS SDALKKKLED AALILKTTYC EMPNYDAVIS
560 570 580 590 600
AMLKHGLEEL PKHCKLTPGT PLKPMLAHPT KGVSEVLRRF EGAEFTCEYK
610 620 630 640 650
YDGERAQIHM LENGEIHIYS RNQENNTSKY PDIIERMPKV NHDDVTSCII
660 670 680 690 700
DSEAVAWDPE NKKILPFQVL STRKRKDADQ SEIKVQVCVY AFDLLYLNGQ
710 720 730 740 750
SLVREPFRKR REMLRESFNE VEGEFVFATS MVSGNTEEIA VFLDASIKDS
760 770 780 790 800
CEGLMVKTLD KDATYEIAKR SHNWLKLKKD YLDGVGDTLD VVPIGGFLGT
810 820 830 840 850
GKRTGKYGGF LLACYSEEDE EFQSICKIGT GFKDEELEQH TEFFKNHVVD
860 870 880 890 900
KPKSYYRYDS SVEPDHWFDA VQVWEIKCAD LSISPVHKAA EGIVDPEKGI
910 920 930 940 950
SLRFPRFLRI RDDKKPEEAT SAQQVAEMYR NQDQVKNQQS NEKSEPADDD

FY
Length:952
Mass (Da):106,658
Last modified:July 28, 2009 - v1
Checksum:iF0778CE028E3CAF7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG666591 Genomic DNA Translation: EEN51399.1
RefSeqiXP_002595387.1, XM_002595341.1
UniGeneiBfl.7211

Genome annotation databases

GeneIDi7228935
KEGGibfo:BRAFLDRAFT_69217

Similar proteinsi

Entry informationi

Entry nameiC3Z7P4_BRAFL
AccessioniPrimary (citable) accession number: C3Z7P4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: March 28, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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