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Protein

DNA ligase

Gene

BRAFLDRAFT_118305

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:BRAFLDRAFT_118305Imported
OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)Imported
Taxonomic identifieri7739 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma
ProteomesiUP000001554 Componenti: Partially assembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7739.JGI118305.

Structurei

3D structure databases

ProteinModelPortaliC3YZ01.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiNOG148750.
InParanoidiC3YZ01.
KOiK10777.
OMAiISHFLCA.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C3YZ01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVAATVPFS HLSIRSLVET TKLMCNLICL TGELAVRAAW KHGEDSFYPA
60 70 80 90 100
MRLILPQCER ERIAYGIKEF TLAKYYIEIL GLAKDSSDAL KLLKYRAPSH
110 120 130 140 150
AKGEAGDFAA VAYFVLKNRC PEKGSLTIQE VNDLLDSIAT NNAAKNKEEV
160 170 180 190 200
RRSILKLLRS TSAMEQELKM GMNQAGVFAV FHPDAEDLFN VTNSLAKVCT
210 220 230 240 250
DLFDPHVRLN EIAISLFSPF KPMLGQRIPL DGVEKEMHHE MFYIETKFDG
260 270 280 290 300
ERMLLHKNGD TYKYFSRSGK DYTHQFGAHP LEGSLTPYIH NCFASHVKSC
310 320 330 340 350
ILDGEMVGYN PQTKSIMSKG DKFDIKNMAE DSDLQTMYCV FDILLLNGQK
360 370 380 390 400
FANSPLRERV DYLDKLFTPI EGRLFLGDRK EARTKAEVID ALNEAIDRRE
410 420 430 440 450
EGLVIKYPGS KYAPDKRKGS GWLKVKPEYV DGLMDQVDVV IVGGYFGKGR
460 470 480 490 500
RSHMISHFLC AVAVQSNTPG DKPALFHTFC RVGSGYTLKE LYQMGQRLHP
510 520 530 540 550
HWRVFDKKKP PKTNIMFPSG YKEAPDVWID PEQSLIVQIK AAEIIESDKF
560 570 580 590 600
KTGCTLRFPR LEKVRDDKEW FDCMTLEELD DMRKVSTIFE DREFCIINGP
610 620 630 640 650
LEHGKADLER KVVAYGGTVV QAPGPDTSCV LAHKVNVRVN NIISGGKYDV
660 670 680 690 700
VKADWLLRCW EAKQCLPWLP SHMIHMSPDT AAQFALEFDR HGCMLTTVML
710 720 730 740 750
LETSQQIKDC PLDLVALEAR FHGATVSPIL DSDVTHVLFH TSDLSRLDEV
760 770 780 790
KALRRQRTKK HHLVTPAWVS ECIQAGAMLT ERDYEPYSTT AST
Length:793
Mass (Da):89,706
Last modified:July 28, 2009 - v1
Checksum:i97E31284FC115917
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG666565 Genomic DNA. Translation: EEN54509.1.
RefSeqiXP_002598497.1. XM_002598451.1.

Genome annotation databases

GeneIDi7219915.
KEGGibfo:BRAFLDRAFT_118305.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG666565 Genomic DNA. Translation: EEN54509.1.
RefSeqiXP_002598497.1. XM_002598451.1.

3D structure databases

ProteinModelPortaliC3YZ01.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7739.JGI118305.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7219915.
KEGGibfo:BRAFLDRAFT_118305.

Phylogenomic databases

eggNOGiNOG148750.
InParanoidiC3YZ01.
KOiK10777.
OMAiISHFLCA.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S238N-H82Imported.
    Tissue: TestesImported.

Entry informationi

Entry nameiC3YZ01_BRAFL
AccessioniPrimary (citable) accession number: C3YZ01
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: June 24, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.