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C3YWU0 (FUCO_BRAFL) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Alpha-L-fucosidase

EC=3.2.1.51
Alternative name(s):
Alpha-L-fucoside fucohydrolase
Gene names
ORF Names:BRAFLDRAFT_56888
OrganismBranchiostoma floridae (Florida lancelet) (Amphioxus) [Reference proteome]
Taxonomic identifier7739 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma

Protein attributes

Sequence length449 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins By similarity.

Catalytic activity

An alpha-L-fucoside + H2O = L-fucose + an alcohol.

Subunit structure

Homotetramer By similarity.

Subcellular location

Secreted Probable.

Sequence similarities

Belongs to the glycosyl hydrolase 29 family.

Sequence caution

The sequence EEN55334.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processfucose metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionalpha-L-fucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 449430Alpha-L-fucosidase
PRO_0000406973

Amino acid modifications

Glycosylation1561N-linked (GlcNAc...) Potential
Glycosylation2241N-linked (GlcNAc...) Potential
Glycosylation3621N-linked (GlcNAc...) Potential
Glycosylation3751N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
C3YWU0 [UniParc].

Last modified April 5, 2011. Version 2.
Checksum: 932A818CAAF41315

FASTA44951,880
        10         20         30         40         50         60 
MGLLLLLSLL SACFQPRYAP TWDSLDQRPL PSWYDEAKFG IFMHWGVFSV PSFGSEWFWW 

        70         80         90        100        110        120 
DWKGAHDQNF IKDFMKRNYP PGFRYADFAP MFTAEWYNPL QWAEVLQASG AKYVVLTSKH 

       130        140        150        160        170        180 
HEGFTNWPSK YSWNWNSVDN GPHRDLVGEL AMAIRNNSDL HFGLYYSLFE WFHPLYLKDK 

       190        200        210        220        230        240 
QNKWTTQDYT KDVGLAELYE LVNAYHPEVV WSDGDWEAPY TYWNSTNFLA WLYNDSPVKD 

       250        260        270        280        290        300 
TVVTNDRWGS GMLCHHGGYY TCSDRYNPGV LQKHKWENCM TIDKKSWGFR REATLADYLD 

       310        320        330        340        350        360 
MDDLVKILAE TVSCGGNLLM NIGPTHDGRI VPIFEERLRS MGKWLQVNGD AIYATKPWRA 

       370        380        390        400        410        420 
QNDTRESGVW YTSKNDSVYA IVLDWPNSGQ LTLGVPRSSP TTTVTMLGWA APLKWVAVSG 

       430        440 
SGITVQMPTA SSNQLPCQWA WVIRMKGVM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GG666561 Genomic DNA. Translation: EEN55334.1. Sequence problems.
RefSeqXP_002599322.1. XM_002599276.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7739.JGI56888.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7207966.
KEGGbfo:BRAFLDRAFT_56888.

Phylogenomic databases

eggNOGCOG3669.
KOK01206.

Family and domain databases

Gene3D2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProIPR016286. FUC_metazoa-typ.
IPR013780. Glyco_hydro_13_b.
IPR000933. Glyco_hydro_29.
IPR018526. Glyco_hydro_29_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR10030. PTHR10030. 1 hit.
PfamPF01120. Alpha_L_fucos. 1 hit.
[Graphical view]
PIRSFPIRSF001092. Alpha-L-fucosidase. 1 hit.
PRINTSPR00741. GLHYDRLASE29.
SMARTSM00812. Alpha_L_fucos. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
PROSITEPS00385. ALPHA_L_FUCOSIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFUCO_BRAFL
AccessionPrimary (citable) accession number: C3YWU0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 19, 2014
This is version 27 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries