C3YMX4 (C3YMX4_BRAFL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pyrroline-5-carboxylate reductase RuleBase RU003903
EC=1.5.1.2 RuleBase RU003903

Gene names

ORF Names:

BRAFLDRAFT_63455 EMBL EEN58465.1

Organism

Branchiostoma floridae (Florida lancelet) (Amphioxus)

Taxonomic identifier

7739 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Cephalochordata › Branchiostomidae › Branchiostoma

Protein attributes

Sequence length	268 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H. RuleBase RU003903
Pathway	Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1. RuleBase RU003903
Sequence similarities	Belongs to the pyrroline-5-carboxylate reductase family. RuleBase RU003903

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Proline biosynthesis RuleBase RU003903
Ligand	NADP RuleBase RU003903
Molecular function	Oxidoreductase RuleBase RU003903
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proline biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro pyrroline-5-carboxylate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3YMX4 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 65C440AAB1A00194	FASTA	268	28,166
	10 20 30 40 50 60 MSLAFVGAGK MAQAMAKGFL AAGVVKADHI TATAPSCRSQ PTLEDIGCQF THNNKEAVEN 70 80 90 100 110 120 SDIIFLSVKP HILPGVLQEI APVVTKRHLM VSVAAGVPLQ FLEEKLPPKS RVMRVMPNTP 130 140 150 160 170 180 CVVRQGASVY VPGSHVEKED SEIIKSLLSS LGYCSESNEG MISAVTGLAG SGPAYAFTAI 190 200 210 220 230 240 DALADGGVKM GLPRELSIKL AAQTLLGASK MVLETGKHPM QLKDDVCSPG GTTIYAIHKL 250 260 ESGGFRNLLI DAVEGACLRA EAIAKKSK

References

[1]

"The amphioxus genome and the evolution of the chordate karyotype." US DOE Joint Genome Institute (JGI-PGF) Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U., Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K., Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J., Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J. , Kapitonov V.V., Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A., Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T., Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H., Satoh N., Rokhsar D.S. Nature 453:1064-1071(2008) [PubMed: 18563158] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S238N-H82 EMBL EEN58465.1. Tissue: Testes EMBL EEN58465.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GG666531 Genomic DNA. Translation: EEN58465.1.
RefSeq	XP_002602453.1. XM_002602407.1.
3D structure databases
ProteinModelPortal	C3YMX4.
ModBase	Search...
Protein-protein interaction databases
STRING	C3YMX4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7207736.
KEGG	bfo:BRAFLDRAFT_63455.
Phylogenomic databases
OMA	RTFNEHQ.
PhylomeDB	C3YMX4.
Family and domain databases
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR016040. NAD(P)-bd_dom. IPR004455. NADP_OxRdtase_F420. IPR000304. Pyrroline-COOH_reductase. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00286.
PANTHER	PTHR11645. P5CR. 1 hit.
Pfam	PF03807. F420_oxidored. 1 hit. [Graphical view]
PIRSF	PIRSF000193. Pyrrol-5-carb_rd. 1 hit.
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR00112. ProC. 1 hit.
PROSITE	PS00521. P5CR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C3YMX4_BRAFL

Accession

Primary (citable) accession number: C3YMX4

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)