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C3YM52

- C3YM52_BRAFL

UniProt

C3YM52 - C3YM52_BRAFL

Protein

Histone deacetylase

Gene

BRAFLDRAFT_281552

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (28 Jul 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

    GO - Molecular functioni

    1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
    2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
    3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
    4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
    Gene namesi
    ORF Names:BRAFLDRAFT_281552Imported
    OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)Imported
    Taxonomic identifieri7739 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma
    ProteomesiUP000001554: Partially assembled WGS sequence

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi7739.JGI281552.

    Structurei

    3D structure databases

    ProteinModelPortaliC3YM52.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0123.
    KOiK11404.
    OMAiNFHYGPG.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSiPR01270. HDASUPER.
    PR01271. HISDACETLASE.

    Sequencei

    Sequence statusi: Complete.

    C3YM52-1 [UniParc]FASTAAdd to Basket

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    MGSTKTVAYF FDPDVGNFHY GQGHPMKPHR LALTHSLVLH YGLYKRMQVY    50
    RPYRATVHDM CRFHSEDYID FLQRVTPQNV QNFTKSLQQF NVGDDCPVFP 100
    GLFNFCSMYT GATLEGAVKL NNNICDIAVN WAGGLHHAKK FEASGFCYVN 150
    DIVIGILELL KYHPRVLYVD IDIHHGDGVQ EAFYLTDRVM TVSFHKYGNH 200
    FFPGTGDMYE VGAEGGKYYS LNVPLKDGID DHNYRQLFNP IMQQVVEFFR 250
    PTCIVLQCGA DSLGCDRLGC FNLSVKGHGE CVSFMKGFNL PLLVLGGGGY 300
    TVRNVARCWT HETALLLDEE VNNELPYNEY FEYFSPDFTL HPDTSTRIEN 350
    CNTKGYLEQI RQTINDNLKS LSHAPSVQMH DIPPDLFSLE VVEEPDPDIR 400
    ESVQDQDNRI EPANEYYDGD KDQDRDNDLD V 431
    Length:431
    Mass (Da):49,185
    Last modified:July 28, 2009 - v1
    Checksum:i9B647A80C9E8953C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG666529 Genomic DNA. Translation: EEN58646.1.
    RefSeqiXP_002602634.1. XM_002602588.1.
    UniGeneiBfl.13769.

    Genome annotation databases

    GeneIDi7235651.
    KEGGibfo:BRAFLDRAFT_281552.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG666529 Genomic DNA. Translation: EEN58646.1 .
    RefSeqi XP_002602634.1. XM_002602588.1.
    UniGenei Bfl.13769.

    3D structure databases

    ProteinModelPortali C3YM52.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7739.JGI281552.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 7235651.
    KEGGi bfo:BRAFLDRAFT_281552.

    Phylogenomic databases

    eggNOGi COG0123.
    KOi K11404.
    OMAi NFHYGPG.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSi PR01270. HDASUPER.
    PR01271. HISDACETLASE.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: S238N-H82Imported.
      Tissue: TestesImported.

    Entry informationi

    Entry nameiC3YM52_BRAFL
    AccessioniPrimary (citable) accession number: C3YM52
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 28, 2009
    Last sequence update: July 28, 2009
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3