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Protein

Histone deacetylase

Gene

BRAFLDRAFT_281552

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorUniRule annotationSAAS annotation, HydrolaseUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseUniRule annotationSAAS annotation (EC:3.5.1.98UniRule annotationSAAS annotation)
Gene namesi
ORF Names:BRAFLDRAFT_281552Imported
OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)Imported
Taxonomic identifieri7739 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma
Proteomesi
  • UP000001554 Componenti: Partially assembled WGS sequence

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7739.JGI281552.

Structurei

3D structure databases

ProteinModelPortaliC3YM52.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 315Hist_deacetylInterPro annotationAdd BLAST292

Sequence similaritiesi

Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG1342. Eukaryota.
COG0123. LUCA.
InParanoidiC3YM52.
KOiK11404.
OMAiQLNHKIC.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiView protein in InterPro
IPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiView protein in Pfam
PF00850. Hist_deacetyl. 1 hit.
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.

Sequencei

Sequence statusi: Complete.

C3YM52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSTKTVAYF FDPDVGNFHY GQGHPMKPHR LALTHSLVLH YGLYKRMQVY
60 70 80 90 100
RPYRATVHDM CRFHSEDYID FLQRVTPQNV QNFTKSLQQF NVGDDCPVFP
110 120 130 140 150
GLFNFCSMYT GATLEGAVKL NNNICDIAVN WAGGLHHAKK FEASGFCYVN
160 170 180 190 200
DIVIGILELL KYHPRVLYVD IDIHHGDGVQ EAFYLTDRVM TVSFHKYGNH
210 220 230 240 250
FFPGTGDMYE VGAEGGKYYS LNVPLKDGID DHNYRQLFNP IMQQVVEFFR
260 270 280 290 300
PTCIVLQCGA DSLGCDRLGC FNLSVKGHGE CVSFMKGFNL PLLVLGGGGY
310 320 330 340 350
TVRNVARCWT HETALLLDEE VNNELPYNEY FEYFSPDFTL HPDTSTRIEN
360 370 380 390 400
CNTKGYLEQI RQTINDNLKS LSHAPSVQMH DIPPDLFSLE VVEEPDPDIR
410 420 430
ESVQDQDNRI EPANEYYDGD KDQDRDNDLD V
Length:431
Mass (Da):49,185
Last modified:July 28, 2009 - v1
Checksum:i9B647A80C9E8953C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG666529 Genomic DNA. Translation: EEN58646.1.
RefSeqiXP_002602634.1. XM_002602588.1.
UniGeneiBfl.13769.

Genome annotation databases

GeneIDi7235651.
KEGGibfo:BRAFLDRAFT_281552.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG666529 Genomic DNA. Translation: EEN58646.1.
RefSeqiXP_002602634.1. XM_002602588.1.
UniGeneiBfl.13769.

3D structure databases

ProteinModelPortaliC3YM52.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7739.JGI281552.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7235651.
KEGGibfo:BRAFLDRAFT_281552.

Phylogenomic databases

eggNOGiKOG1342. Eukaryota.
COG0123. LUCA.
InParanoidiC3YM52.
KOiK11404.
OMAiQLNHKIC.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiView protein in InterPro
IPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiView protein in Pfam
PF00850. Hist_deacetyl. 1 hit.
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.
ProtoNetiSearch...

Entry informationi

Entry nameiC3YM52_BRAFL
AccessioniPrimary (citable) accession number: C3YM52
Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: May 10, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.