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Protein

Histone deacetylase

Gene

BRAFLDRAFT_281552

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
Gene namesi
ORF Names:BRAFLDRAFT_281552Imported
OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)Imported
Taxonomic identifieri7739 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma
ProteomesiUP000001554 Componenti: Partially assembled WGS sequence

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi7739.JGI281552.

Structurei

3D structure databases

ProteinModelPortaliC3YM52.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0123.
InParanoidiC3YM52.
KOiK11404.
OMAiLFDFCSM.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.

Sequencei

Sequence statusi: Complete.

C3YM52-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSTKTVAYF FDPDVGNFHY GQGHPMKPHR LALTHSLVLH YGLYKRMQVY
60 70 80 90 100
RPYRATVHDM CRFHSEDYID FLQRVTPQNV QNFTKSLQQF NVGDDCPVFP
110 120 130 140 150
GLFNFCSMYT GATLEGAVKL NNNICDIAVN WAGGLHHAKK FEASGFCYVN
160 170 180 190 200
DIVIGILELL KYHPRVLYVD IDIHHGDGVQ EAFYLTDRVM TVSFHKYGNH
210 220 230 240 250
FFPGTGDMYE VGAEGGKYYS LNVPLKDGID DHNYRQLFNP IMQQVVEFFR
260 270 280 290 300
PTCIVLQCGA DSLGCDRLGC FNLSVKGHGE CVSFMKGFNL PLLVLGGGGY
310 320 330 340 350
TVRNVARCWT HETALLLDEE VNNELPYNEY FEYFSPDFTL HPDTSTRIEN
360 370 380 390 400
CNTKGYLEQI RQTINDNLKS LSHAPSVQMH DIPPDLFSLE VVEEPDPDIR
410 420 430
ESVQDQDNRI EPANEYYDGD KDQDRDNDLD V
Length:431
Mass (Da):49,185
Last modified:July 28, 2009 - v1
Checksum:i9B647A80C9E8953C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG666529 Genomic DNA. Translation: EEN58646.1.
RefSeqiXP_002602634.1. XM_002602588.1.
UniGeneiBfl.13769.

Genome annotation databases

GeneIDi7235651.
KEGGibfo:BRAFLDRAFT_281552.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG666529 Genomic DNA. Translation: EEN58646.1.
RefSeqiXP_002602634.1. XM_002602588.1.
UniGeneiBfl.13769.

3D structure databases

ProteinModelPortaliC3YM52.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7739.JGI281552.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7235651.
KEGGibfo:BRAFLDRAFT_281552.

Phylogenomic databases

eggNOGiCOG0123.
InParanoidiC3YM52.
KOiK11404.
OMAiLFDFCSM.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S238N-H82Imported.
    Tissue: TestesImported.

Entry informationi

Entry nameiC3YM52_BRAFL
AccessioniPrimary (citable) accession number: C3YM52
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: July 22, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.