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C3XZ66 (C3XZ66_BRAFL) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Proteasome subunit alpha type RuleBase RU000551
EC=3.4.25.1 RuleBase RU000551
Gene names
ORF Names:BRAFLDRAFT_260512 EMBL EEN66630.1
OrganismBranchiostoma floridae (Florida lancelet) (Amphioxus)
Taxonomic identifier7739 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Cephalochordata › Branchiostomidae › Branchiostoma

Protein attributes

Sequence length246 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity By similarity. RuleBase RU000551

Catalytic activity

Cleavage of peptide bonds with very broad specificity. RuleBase RU000551

Subunit structure

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits By similarity. RuleBase RU000551

Subcellular location

Cytoplasm. Nucleus By similarity RuleBase RU000551.

Sequence similarities

Belongs to the peptidase T1A family. RuleBase RU000551

Sequences

Sequence LengthMass (Da)Tools
C3XZ66 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: C6AEAD35F28307AB

FASTA24627,508
        10         20         30         40         50         60 
MSRGTSAGFD RHITIFSPEG RLYQVEYAFK AVNQGGLTSV AVRGKDCAVV VTQKKVPDKL 

        70         80         90        100        110        120 
LDAETVTHIF QITDYIGCVM TGMIADSRSQ VQRARYEAAN WKYKYGYEIP VDMLCKRIAD 

       130        140        150        160        170        180 
ISQVYTQNAE MRPLGCCMIL IGYDDEHGPQ VYKTDPAGYY CGYKATSVGV KQTEANSFLE 

       190        200        210        220        230        240 
KKIKKKVDFT YNEAVETAIT CLSTILSADF KPTEIEVAVV NKDNPKFRVL TEAEIDTQLV 


SIAERD

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		GG666475 Genomic DNA. Translation: EEN66630.1.
RefSeqXP_002610620.1. XM_002610574.1.
UniGeneBfl.8446.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC3XZ66.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7218346.
KEGGbfo:BRAFLDRAFT_260512.

Phylogenomic databases

OMAGKDCAVV.
PhylomeDBC3XZ66.

Family and domain databases

InterProIPR000426. Proteasome_asu_N.
IPR023332. Proteasome_suA-type.
IPR001353. Proteasome_sua/b.
[Graphical view]
KOK02730.
PfamPF00227. Proteasome. 1 hit.
PF10584. Proteasome_A_N. 1 hit.
[Graphical view]
SMARTSM00948. Proteasome_A_N. 1 hit.
[Graphical view]
PROSITEPS00388. PROTEASOME_A_1. 1 hit.
PS51475. PROTEASOME_A_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC3XZ66_BRAFL
AccessionPrimary (citable) accession number: C3XZ66
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info