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Protein

Histone-lysine N-methyltransferase

Gene

BRAFLDRAFT_231117

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei49S-adenosyl-L-methioninePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotation, Transferase
LigandS-adenosyl-L-methioninePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferasePROSITE-ProRule annotation (EC:2.1.1.43PROSITE-ProRule annotation)
Gene namesi
ORF Names:BRAFLDRAFT_231117Imported
OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)Imported
Taxonomic identifieri7739 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma
Proteomesi
  • UP000001554 Componenti: Partially assembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi7739.JGI231117.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 116SETInterPro annotationAdd BLAST116

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni4 – 6S-adenosyl-L-methionine bindingPROSITE-ProRule annotation3
Regioni76 – 77S-adenosyl-L-methionine bindingPROSITE-ProRule annotation2

Sequence similaritiesi

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. PR/SET subfamily.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1085. Eukaryota.
COG2940. LUCA.
InParanoidiC3XVK0.
KOiK11428.
OMAiFGCYMYY.

Family and domain databases

InterProiView protein in InterPro
IPR016858. Hist_H4-K20_MeTrfase.
IPR001214. SET_dom.
PfamiView protein in Pfam
PF00856. SET. 1 hit.
SMARTiView protein in SMART
SM00317. SET. 1 hit.
PROSITEiView protein in PROSITE
PS51571. SAM_MT43_PR_SET. 1 hit.
PS50280. SET. 1 hit.

Sequencei

Sequence statusi: Fragment.

C3XVK0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IEGKGRGVVA TKAFGRGDFV VEYAGDLIDT KMAKDREAKY AEDPSTGCYM
60 70 80 90 100
YYFKYRNKTY CVDATAESGR LGRLINHSAK HKNLMTRSIS AGGLPRLILV
110 120 130
AARDIQPGEE LQYDYGDRSK ASLESHPWLA C
Length:131
Mass (Da):14,574
Last modified:July 28, 2009 - v1
Checksum:i4374DFA64AEBE010
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG666468 Genomic DNA. Translation: EEN68126.1.
RefSeqiXP_002612117.1. XM_002612071.1.

Genome annotation databases

GeneIDi7248745.
KEGGibfo:BRAFLDRAFT_231117.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG666468 Genomic DNA. Translation: EEN68126.1.
RefSeqiXP_002612117.1. XM_002612071.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7739.JGI231117.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7248745.
KEGGibfo:BRAFLDRAFT_231117.

Phylogenomic databases

eggNOGiKOG1085. Eukaryota.
COG2940. LUCA.
InParanoidiC3XVK0.
KOiK11428.
OMAiFGCYMYY.

Family and domain databases

InterProiView protein in InterPro
IPR016858. Hist_H4-K20_MeTrfase.
IPR001214. SET_dom.
PfamiView protein in Pfam
PF00856. SET. 1 hit.
SMARTiView protein in SMART
SM00317. SET. 1 hit.
PROSITEiView protein in PROSITE
PS51571. SAM_MT43_PR_SET. 1 hit.
PS50280. SET. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiC3XVK0_BRAFL
AccessioniPrimary (citable) accession number: C3XVK0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: May 10, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.