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C3XPG8

- C3XPG8_BRAFL

UniProt

C3XPG8 - C3XPG8_BRAFL

Protein

DNA ligase

Gene

BRAFLDRAFT_119901

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (28 Jul 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC
    4. zinc ion binding Source: InterPro

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:BRAFLDRAFT_119901Imported
    OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)Imported
    Taxonomic identifieri7739 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma
    ProteomesiUP000001554: Partially assembled WGS sequence

    Interactioni

    Protein-protein interaction databases

    STRINGi7739.JGI119901.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1793.
    KOiK10776.
    OMAiLFSEMKH.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1740.10. 1 hit.
    3.40.50.10190. 1 hit.
    InterProiIPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    IPR019406. Znf_C2H2_APLF-like.
    IPR001510. Znf_PARP.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    PF10283. zf-CCHH. 1 hit.
    PF00645. zf-PARP. 1 hit.
    [Graphical view]
    SMARTiSM00292. BRCT. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS50172. BRCT. 1 hit.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    PS00347. PARP_ZN_FINGER_1. 1 hit.
    PS50064. PARP_ZN_FINGER_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C3XPG8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHRENKGLRT SRFCVEYAKQ GRAGCKKCKQ KIEKGLPRIG KIVPNFFHEG    50
    DGEMKQWYHV ACIFETFQRA RATTKKIEDA SDLEGWEDME DEEKQTILKL 100
    IKELESKAKS PKKKVVQATL STKGKIQSPT KKAASSATVS DDSPAAGPSS 150
    SSSASTSVSM TSPTPTPDID HKDNAFREFR RLCALIAEEP GYNAKTKLVS 200
    DFLKKGSNGD GFKGDTFLVV KLLLPGVVKR VYNLNNKQLL KHFANIFGVN 250
    LADMLTDLEL GDVSETVRKF FEESERCLPA KKSKLTIQEV DESLEILAQM 300
    TKEDDQMREL NKIAKKCTAN DLKVVVRLIK HDLRINAGAK HILEGLDPNA 350
    YPAFQASRNL ADVVERVVAN GCAPGMKKSL SIKANLMTPV LPMLAEACKS 400
    VEMAMRKCPN GMYAEIKYDG ERVQVHKQGN KFEYFSRSLK PVLPHKVAHF 450
    KDYIPKAFPH GSNMILDSEV LLVDTNTGNP LPFGTLGIHK KQQFSDAQVA 500
    LFVFDCIYFN GETLMDRPIS ERRKFLEDNM TVIPNRVVLS EYRYITEPGD 550
    LSDMIGRVIR DGLEGLVLKD TKSIYEPGKR HWLKVKKDYL EQGAMADTAD 600
    LVVLGAFYGT GNKGGLKSVF LMGVYDPDSD KWCTVTKCGN GHDDNTIAKL 650
    NKELAMVKIS KDMSKVPKWL KITKNLVPDF VCADPKKAPV WEITGAEFSK 700
    SEAHTADGIS IRFPRVTKIR DDKDWKSATN LKQLKHLFKT SKETSDIPDL 750
    LKGKGKSPRK PVKVKVEEED DDDDDDDDSN GGASSNGVTP IKGMKRKAEE 800
    DSPRTPKKSK PTCRYGATCY QTGKEHLDKF DHPTRKSPKK SNSAAKSVLP 850
    DVFCGIKLFL PDTVENYALL RRYFVAYDGD IVQDYAMSQA THVVEDPEQK 900
    NMNGKTDAQL VTVDWLWQCI KRKQLVPV 928
    Length:928
    Mass (Da):103,861
    Last modified:July 28, 2009 - v1
    Checksum:i3CD9F7EE4715580B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG666451 Genomic DNA. Translation: EEN69839.1.
    RefSeqiXP_002613830.1. XM_002613784.1.
    UniGeneiBfl.20221.

    Genome annotation databases

    GeneIDi7222688.
    KEGGibfo:BRAFLDRAFT_119901.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    GG666451 Genomic DNA. Translation: EEN69839.1 .
    RefSeqi XP_002613830.1. XM_002613784.1.
    UniGenei Bfl.20221.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7739.JGI119901.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 7222688.
    KEGGi bfo:BRAFLDRAFT_119901.

    Phylogenomic databases

    eggNOGi COG1793.
    KOi K10776.
    OMAi LFSEMKH.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1740.10. 1 hit.
    3.40.50.10190. 1 hit.
    InterProi IPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    IPR019406. Znf_C2H2_APLF-like.
    IPR001510. Znf_PARP.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    PF10283. zf-CCHH. 1 hit.
    PF00645. zf-PARP. 1 hit.
    [Graphical view ]
    SMARTi SM00292. BRCT. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS50172. BRCT. 1 hit.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    PS00347. PARP_ZN_FINGER_1. 1 hit.
    PS50064. PARP_ZN_FINGER_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: S238N-H82Imported.
      Tissue: TestesImported.

    Entry informationi

    Entry nameiC3XPG8_BRAFL
    AccessioniPrimary (citable) accession number: C3XPG8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 28, 2009
    Last sequence update: July 28, 2009
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3