C3XPG8 (C3XPG8_BRAFL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

ORF Names:

BRAFLDRAFT_119901 EMBL EEN69839.1

Organism

Branchiostoma floridae (Florida lancelet) (Amphioxus) [Reference proteome] EMBL EEN69839.1

Taxonomic identifier

7739 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Cephalochordata › Branchiostomidae › Branchiostoma

Protein attributes

Sequence length	928 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3XPG8 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 3CD9F7EE4715580B	FASTA	928	103,861
	10 20 30 40 50 60 MHRENKGLRT SRFCVEYAKQ GRAGCKKCKQ KIEKGLPRIG KIVPNFFHEG DGEMKQWYHV 70 80 90 100 110 120 ACIFETFQRA RATTKKIEDA SDLEGWEDME DEEKQTILKL IKELESKAKS PKKKVVQATL 130 140 150 160 170 180 STKGKIQSPT KKAASSATVS DDSPAAGPSS SSSASTSVSM TSPTPTPDID HKDNAFREFR 190 200 210 220 230 240 RLCALIAEEP GYNAKTKLVS DFLKKGSNGD GFKGDTFLVV KLLLPGVVKR VYNLNNKQLL 250 260 270 280 290 300 KHFANIFGVN LADMLTDLEL GDVSETVRKF FEESERCLPA KKSKLTIQEV DESLEILAQM 310 320 330 340 350 360 TKEDDQMREL NKIAKKCTAN DLKVVVRLIK HDLRINAGAK HILEGLDPNA YPAFQASRNL 370 380 390 400 410 420 ADVVERVVAN GCAPGMKKSL SIKANLMTPV LPMLAEACKS VEMAMRKCPN GMYAEIKYDG 430 440 450 460 470 480 ERVQVHKQGN KFEYFSRSLK PVLPHKVAHF KDYIPKAFPH GSNMILDSEV LLVDTNTGNP 490 500 510 520 530 540 LPFGTLGIHK KQQFSDAQVA LFVFDCIYFN GETLMDRPIS ERRKFLEDNM TVIPNRVVLS 550 560 570 580 590 600 EYRYITEPGD LSDMIGRVIR DGLEGLVLKD TKSIYEPGKR HWLKVKKDYL EQGAMADTAD 610 620 630 640 650 660 LVVLGAFYGT GNKGGLKSVF LMGVYDPDSD KWCTVTKCGN GHDDNTIAKL NKELAMVKIS 670 680 690 700 710 720 KDMSKVPKWL KITKNLVPDF VCADPKKAPV WEITGAEFSK SEAHTADGIS IRFPRVTKIR 730 740 750 760 770 780 DDKDWKSATN LKQLKHLFKT SKETSDIPDL LKGKGKSPRK PVKVKVEEED DDDDDDDDSN 790 800 810 820 830 840 GGASSNGVTP IKGMKRKAEE DSPRTPKKSK PTCRYGATCY QTGKEHLDKF DHPTRKSPKK 850 860 870 880 890 900 SNSAAKSVLP DVFCGIKLFL PDTVENYALL RRYFVAYDGD IVQDYAMSQA THVVEDPEQK 910 920 NMNGKTDAQL VTVDWLWQCI KRKQLVPV

References

[1]

"The amphioxus genome and the evolution of the chordate karyotype." US DOE Joint Genome Institute (JGI-PGF) Putnam N.H., Butts T., Ferrier D.E., Furlong R.F., Hellsten U., Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.K., Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., Gibson-Brown J.J., Grigoriev I.V., Horton A.C., de Jong P.J., Jurka J. , Kapitonov V.V., Kohara Y., Kuroki Y., Lindquist E., Lucas S., Osoegawa K., Pennacchio L.A., Salamov A.A., Satou Y., Sauka-Spengler T., Schmutz J., Shin-I T., Toyoda A., Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W., Satoh N., Rokhsar D.S. Nature 453:1064-1071(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S238N-H82 EMBL EEN69839.1. Tissue: Testes EMBL EEN69839.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GG666451 Genomic DNA. Translation: EEN69839.1.
RefSeq	XP_002613830.1. XM_002613784.1.
UniGene	Bfl.20221.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7222688.
KEGG	bfo:BRAFLDRAFT_119901.
Phylogenomic databases
eggNOG	COG1793.
KO	K10776.
OMA	WSETDLL.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit. 2.40.50.140. 1 hit. 3.30.1740.10. 1 hit. 3.40.50.10190. 1 hit.
InterPro	IPR001357. BRCT_dom. IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. IPR019406. Znf_C2H2_APLF-like. IPR001510. Znf_PARP. [Graphical view]
Pfam	PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. PF10283. zf-CCHH. 1 hit. PF00645. zf-PARP. 1 hit. [Graphical view]
SMART	SM00292. BRCT. 1 hit. [Graphical view]
SUPFAM	SSF52113. BRCT. 1 hit. SSF50249. Nucleic_acid_OB. 1 hit. SSF117018. SSF117018. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS50172. BRCT. 1 hit. PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. PS00347. PARP_ZN_FINGER_1. 1 hit. PS50064. PARP_ZN_FINGER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C3XPG8_BRAFL

Accession

Primary (citable) accession number: C3XPG8

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	May 29, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)