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C3XPG8

- C3XPG8_BRAFL

UniProt

C3XPG8 - C3XPG8_BRAFL

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Protein
DNA ligase
Gene
BRAFLDRAFT_119901
Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC
  4. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:BRAFLDRAFT_119901Imported
OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)Imported
Taxonomic identifieri7739 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma
ProteomesiUP000001554: Partially assembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi7739.JGI119901.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1793.
KOiK10776.
OMAiLFSEMKH.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.30.1740.10. 1 hit.
3.40.50.10190. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
IPR019406. Znf_C2H2_APLF-like.
IPR001510. Znf_PARP.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
PF10283. zf-CCHH. 1 hit.
PF00645. zf-PARP. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
PS00347. PARP_ZN_FINGER_1. 1 hit.
PS50064. PARP_ZN_FINGER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C3XPG8-1 [UniParc]FASTAAdd to Basket

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MHRENKGLRT SRFCVEYAKQ GRAGCKKCKQ KIEKGLPRIG KIVPNFFHEG    50
DGEMKQWYHV ACIFETFQRA RATTKKIEDA SDLEGWEDME DEEKQTILKL 100
IKELESKAKS PKKKVVQATL STKGKIQSPT KKAASSATVS DDSPAAGPSS 150
SSSASTSVSM TSPTPTPDID HKDNAFREFR RLCALIAEEP GYNAKTKLVS 200
DFLKKGSNGD GFKGDTFLVV KLLLPGVVKR VYNLNNKQLL KHFANIFGVN 250
LADMLTDLEL GDVSETVRKF FEESERCLPA KKSKLTIQEV DESLEILAQM 300
TKEDDQMREL NKIAKKCTAN DLKVVVRLIK HDLRINAGAK HILEGLDPNA 350
YPAFQASRNL ADVVERVVAN GCAPGMKKSL SIKANLMTPV LPMLAEACKS 400
VEMAMRKCPN GMYAEIKYDG ERVQVHKQGN KFEYFSRSLK PVLPHKVAHF 450
KDYIPKAFPH GSNMILDSEV LLVDTNTGNP LPFGTLGIHK KQQFSDAQVA 500
LFVFDCIYFN GETLMDRPIS ERRKFLEDNM TVIPNRVVLS EYRYITEPGD 550
LSDMIGRVIR DGLEGLVLKD TKSIYEPGKR HWLKVKKDYL EQGAMADTAD 600
LVVLGAFYGT GNKGGLKSVF LMGVYDPDSD KWCTVTKCGN GHDDNTIAKL 650
NKELAMVKIS KDMSKVPKWL KITKNLVPDF VCADPKKAPV WEITGAEFSK 700
SEAHTADGIS IRFPRVTKIR DDKDWKSATN LKQLKHLFKT SKETSDIPDL 750
LKGKGKSPRK PVKVKVEEED DDDDDDDDSN GGASSNGVTP IKGMKRKAEE 800
DSPRTPKKSK PTCRYGATCY QTGKEHLDKF DHPTRKSPKK SNSAAKSVLP 850
DVFCGIKLFL PDTVENYALL RRYFVAYDGD IVQDYAMSQA THVVEDPEQK 900
NMNGKTDAQL VTVDWLWQCI KRKQLVPV 928
Length:928
Mass (Da):103,861
Last modified:July 28, 2009 - v1
Checksum:i3CD9F7EE4715580B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GG666451 Genomic DNA. Translation: EEN69839.1.
RefSeqiXP_002613830.1. XM_002613784.1.
UniGeneiBfl.20221.

Genome annotation databases

GeneIDi7222688.
KEGGibfo:BRAFLDRAFT_119901.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GG666451 Genomic DNA. Translation: EEN69839.1 .
RefSeqi XP_002613830.1. XM_002613784.1.
UniGenei Bfl.20221.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 7739.JGI119901.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 7222688.
KEGGi bfo:BRAFLDRAFT_119901.

Phylogenomic databases

eggNOGi COG1793.
KOi K10776.
OMAi LFSEMKH.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.30.1740.10. 1 hit.
3.40.50.10190. 1 hit.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
IPR019406. Znf_C2H2_APLF-like.
IPR001510. Znf_PARP.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
PF10283. zf-CCHH. 1 hit.
PF00645. zf-PARP. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 1 hit.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
PS00347. PARP_ZN_FINGER_1. 1 hit.
PS50064. PARP_ZN_FINGER_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S238N-H82Imported.
    Tissue: TestesImported.

Entry informationi

Entry nameiC3XPG8_BRAFL
AccessioniPrimary (citable) accession number: C3XPG8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: March 19, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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