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Protein
Submitted name:

Large conductance Ca2+-activated potassium channel DEC variant 1

Gene

Kcnma1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Potassium channelSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transport, Transport

Keywords - Ligandi

Potassium

Names & Taxonomyi

Protein namesi
Submitted name:
Large conductance Ca2+-activated potassium channel DEC variant 1Imported
Gene namesi
Name:Kcnma1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99923. Kcnma1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei20 – 4324HelicalSequence analysisAdd
BLAST
Transmembranei114 – 13219HelicalSequence analysisAdd
BLAST
Transmembranei152 – 17019HelicalSequence analysisAdd
BLAST
Transmembranei235 – 25622HelicalSequence analysisAdd
BLAST
Transmembranei271 – 29020HelicalSequence analysisAdd
BLAST
Transmembranei302 – 32019HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiC3VLD3.
PeptideAtlasiC3VLD3.

Interactioni

Protein-protein interaction databases

IntActiC3VLD3. 1 interaction.
STRINGi10090.ENSMUSP00000136447.

Structurei

3D structure databases

ProteinModelPortaliC3VLD3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini117 – 327211Ion_transInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1420. Eukaryota.
ENOG410YUX1. LUCA.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR005821. Ion_trans_dom.
IPR003929. K_chnl_Ca-activ_BK_asu.
IPR016040. NAD(P)-bd_dom.
IPR028325. VG_K_chnl.
[Graphical view]
PfamiPF03493. BK_channel_a. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01449. BKCHANNELA.
PR00169. KCHANNEL.
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

C3VLD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDALIIPVTM EVPCDSRGQR MWWAFLASSM VTFFGGLFII LLWRTLKYLW
60 70 80 90 100
TVCCHCGGKT KEAQKINNGS SQADGTLKPV DEKEEVVAAE VGWMTSVKDW
110 120 130 140 150
AGVMISAQTL TGRVLVVLVF ALSIGALVIY FIDSSNPIES CQNFYKDFTL
160 170 180 190 200
QIDMAFNVFF LLYFGLRFIA ANDKLWFWLE VNSVVDFFTV PPVFVSVYLN
210 220 230 240 250
RSWLGLRFLR ALRLIQFSEI LQFLNILKTS NSIKLVNLLS IFISTWLTAA
260 270 280 290 300
GFIHLVENSG DPWENFQNNQ ALTYWECVYL LMVTMSTVGY GDVYAKTTLG
310 320 330 340 350
RLFMVFFILG GLAMFASYVP EIIELIGNRK KYGGSYSAVS GRKHIVVCGH
360 370 380 390 400
ITLESVSNFL KDFLHKDRDD VNVEIVFLHN ISPNLELEAL FKRHFTQVEF
410 420 430 440 450
YQGSVLNPHD LARVKIESAD ACLILANKYC ADPDAEDASN IMRVISIKNY
460 470 480 490 500
HPKIRIITQM LQYHNKAHLL NIPSWNWKEG DDAICLAELK LGFIAQSCLA
510 520 530 540 550
QGLSTMLANL FSMRSFIKIE EDTWQKYYLE GVSNEMYTEY LSSAFVGLSF
560 570 580 590 600
PTVCELCFVK LKLLMIAIEY KSANRESRIL INPGNHLKIQ EGTLGFFIAS
610 620 630 640 650
DAKEVKRAFF YCKACHDDVT DPKRIKKCGC RRLIYFEDEQ PPTLSPKKKQ
660 670 680 690 700
RNGGMRNSPN TSPKLMRHDP LLIPGNDQID NMDSNVKKYD STGMFHWCAP
710 720 730 740 750
KEIEKVILTR SEAAMTVLSG HVVVCIFGDV SSALIGLRNL VMPLRASNFH
760 770 780 790 800
YHELKHIVFV GSIEYLKREW ETLHNFPKVS ILPGTPLSRA DLRAVNINLC
810 820 830 840 850
DMCVILSANQ NNIDDTSLQD KECILASLNI KSMQFDDSIG VLQANSQGFT
860 870 880 890 900
PPGMDRSSPD NSPVHGMLRQ PSITTGVNIP IITELAKPGK LPLVSVNQEK
910 920 930 940 950
NSGTHILMIT ELVNDTNVQF LDQDDDDDPD TELYLTQPFA CGTAFAVSVL
960 970 980 990 1000
DSLMSATYFN DNILTLIRTL VTGGATPELE ALIAEENALR GGYSTPQTLA
1010 1020 1030 1040 1050
NRDRCRVAQL ALLDGPFADL GDGGCYGDLF CKALKTYNML CFGIYRLRDA
1060 1070 1080 1090 1100
HLSTPSQCTK RYVITNPPYE FELVPTDLIF CLMQFDHNAG QSRASLSHSS
1110 1120 1130 1140 1150
HSSQSSSKKS SSVHSIPSTA NRPNRPKSRE SRDKQNATRM TRMGQEKKWF
1160 1170 1180 1190
TDEPDNAYPR NIQIKPMSTH MANQINQYKS TSSLIPPIRE VEDEC
Length:1,195
Mass (Da):134,534
Last modified:June 16, 2009 - v1
Checksum:i5BC29C3DE581277A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ872117 mRNA. Translation: ACP74150.1.
UniGeneiMm.343607.
Mm.486347.

Genome annotation databases

UCSCiuc011zgv.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ872117 mRNA. Translation: ACP74150.1.
UniGeneiMm.343607.
Mm.486347.

3D structure databases

ProteinModelPortaliC3VLD3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiC3VLD3. 1 interaction.
STRINGi10090.ENSMUSP00000136447.

Proteomic databases

PaxDbiC3VLD3.
PeptideAtlasiC3VLD3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc011zgv.2. mouse.

Organism-specific databases

MGIiMGI:99923. Kcnma1.

Phylogenomic databases

eggNOGiKOG1420. Eukaryota.
ENOG410YUX1. LUCA.

Miscellaneous databases

ChiTaRSiKcnma1. mouse.
SOURCEiSearch...

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR005821. Ion_trans_dom.
IPR003929. K_chnl_Ca-activ_BK_asu.
IPR016040. NAD(P)-bd_dom.
IPR028325. VG_K_chnl.
[Graphical view]
PfamiPF03493. BK_channel_a. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR01449. BKCHANNELA.
PR00169. KCHANNEL.
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiC3VLD3_MOUSE
AccessioniPrimary (citable) accession number: C3VLD3
Entry historyi
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: September 7, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.