C3TD52 (C3TD52_ECOLX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
D-amino acid dehydrogenase small subunit 1 HAMAP MF_01202
EC=1.4.99.1 HAMAP MF_01202

Gene names

Name:	dadA1 HAMAP MF_01202
ORF Names:	ECs1684 EMBL ACI84636.1

Organism

Escherichia coli EMBL ACI84636.1

Taxonomic identifier

562 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	432 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity. SAAS SAAS023080 HAMAP MF_01202
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. SAAS SAAS023080 HAMAP MF_01202
Cofactor	FAD By similarity. SAAS SAAS023080 HAMAP MF_01202
Pathway	Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202
Subunit structure	Heterodimer of a small and a large subunit By similarity. SAAS SAAS023080 HAMAP MF_01202
Sequence similarities	Belongs to the DadA oxidoreductase family. HAMAP MF_01202

Ontologies

Keywords
Ligand	FAD SAAS SAAS023080 HAMAP MF_01202 Flavoprotein SAAS SAAS023080 HAMAP MF_01202
Molecular function	Oxidoreductase SAAS SAAS023080 HAMAP MF_01202
Gene Ontology (GO)
Biological process	alanine catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3TD52 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: EE747358845B6280	FASTA	432	47,607
	10 20 30 40 50 60 MRVVILGSGV VGVASAWYLN QAGHEVTVID REPGAALETS AANAGQISPG YAAPWAAPGV 70 80 90 100 110 120 PLKAIKWMFQ RHAPLAVRLD GTQFQLKWMW QMLRNCDTSH YMENKGRMVR LAEYSRDCLK 130 140 150 160 170 180 ALRAETNIQY EGRQGGTLQL FRTEQQYENA TRDIAVLEDA GVPYQLLESS RLAEVEPALA 190 200 210 220 230 240 EVAHKLTGGL QLPNDETGDC QLFTQNLARM AEQAGVKFRF NTPVDQLLCD GEQIYGVKCG 250 260 270 280 290 300 DEVIKADAYV MAFGSYSTAM LKGIVDIPVY PLKGYSLTIP IAQEDGAPVS TILDETYKIA 310 320 330 340 350 360 ITRFDNRIRV GGMAEIVGFN TELLQPRRET LEMVVRDLYP RGGHVEQATF WTGLRPMTPD 370 380 390 400 410 420 GTPVVGRTRF KNLWLNTGHG TLGWTMACGS GQLLSDLLSG RTPAIPYEDL SVARYSRGFT 430 PSRPGHLHGA HS

References

[1]

"A precise reconstruction of the emergence and constrained radiations of Escherichia coli O157 portrayed by backbone concatenomic analysis." Leopold S.R., Magrini V., Holt N.J., Shaikh N., Mardis E.R., Cagno J., Ogura Y., Iguchi A., Hayashi T., Mellmann A., Karch H., Besser T.E., Sawyer S.A., Whittam T.S., Tarr P.I. Proc. Natl. Acad. Sci. U.S.A. 106:8713-8718(2009) [PubMed: 19439656] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 493/89 EMBL ACI84636.1, 86-24 EMBL ACI84637.1, 87-14 EMBL ACI84638.1 and TW14359 EMBL ACI84640.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EU902090 Genomic DNA. Translation: ACI84636.1. EU902091 Genomic DNA. Translation: ACI84637.1. EU902092 Genomic DNA. Translation: ACI84638.1. EU902094 Genomic DNA. Translation: ACI84640.1.
3D structure databases
ProteinModelPortal	C3TD52.
SMR	C3TD52. Positions 2-34, 200-257.
ModBase	Search...
Proteomic databases
PRIDE	C3TD52.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
HAMAP	MF_01202. DadA. [Tree]
InterPro	IPR023080. D-aa_DH_ssu_DadA. IPR006076. FAD-dep_OxRdtase. [Graphical view]
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C3TD52_ECOLX

Accession

Primary (citable) accession number: C3TD52

Entry history

Integrated into UniProtKB/TrEMBL:	June 16, 2009
Last sequence update:	June 16, 2009
Last modified:	January 25, 2012
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)