C3T6W7 (C3T6W7_ECOLX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400
EC=1.8.4.12 HAMAP MF_01400

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase HAMAP MF_01400

Gene names

Name:	msrB HAMAP MF_01400 EMBL CAP76271.1
ORF Names:	ECs2487 EMBL ACI82451.1, LF82_1402 EMBL CAP76271.1

Organism

Escherichia coli EMBL ACI82451.1

Taxonomic identifier

562 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	137 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family. HAMAP MF_01400

Ontologies

Keywords
Ligand	Metal-binding HAMAP MF_01400 Zinc HAMAP MF_01400
Molecular function	Oxidoreductase SAAS SAAS002579 HAMAP MF_01400
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3T6W7 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 7B9B783DBEBE0F71	FASTA	137	15,451
	10 20 30 40 50 60 MANKPSAEEL KKNLSEMQFY VTQNHGTEPP FTGRLLHNKR DGVYHCLICD APLFHSQTKY 70 80 90 100 110 120 DSGCGWPSFY EPVSEESIRY IKDLSHGMQR IEIRCGNCDA HLGHVFPDGP QPTGERYCVN 130 SASLRFTDGE NGEEING

References

[1]	"A precise reconstruction of the emergence and constrained radiations of Escherichia coli O157 portrayed by backbone concatenomic analysis." Leopold S.R., Magrini V., Holt N.J., Shaikh N., Mardis E.R., Cagno J., Ogura Y., Iguchi A., Hayashi T., Mellmann A., Karch H., Besser T.E., Sawyer S.A., Whittam T.S., Tarr P.I. Proc. Natl. Acad. Sci. U.S.A. 106:8713-8718(2009) [PubMed: 19439656] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 493/89 EMBL ACI82451.1, 86-24 EMBL ACI82452.1, 87-14 EMBL ACI82453.1, TB182A EMBL ACI82454.1 and TW14359 EMBL ACI82455.1.
[2]	"Complete genome sequence of adherent invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease." Peyretaillade E., Claret L., Bonnet R., Dossat C., Barbe V., Vacherie B., Segurens B., Peyret P., Darfeuille-Michaud A. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: LF82 EMBL CAP76271.1.
[3]	Genoscope - CEA Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: LF82 EMBL CAP76271.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EU899900 Genomic DNA. Translation: ACI82451.1. EU899901 Genomic DNA. Translation: ACI82452.1. EU899902 Genomic DNA. Translation: ACI82453.1. EU899903 Genomic DNA. Translation: ACI82454.1. EU899904 Genomic DNA. Translation: ACI82455.1. CU651637 Genomic DNA. Translation: CAP76271.1.
3D structure databases
ProteinModelPortal	C3T6W7.
SMR	C3T6W7. Positions 3-134.
ModBase	Search...
Proteomic databases
PRIDE	C3T6W7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	48653425. VBIEscCol74806_1773.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C3T6W7_ECOLX

Accession

Primary (citable) accession number: C3T6W7

Entry history

Integrated into UniProtKB/TrEMBL:	June 16, 2009
Last sequence update:	June 16, 2009
Last modified:	January 25, 2012
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)