Skip Header

Contribute Send feedback
Read comments (?) or add your own

C3T562 (C3T562_ECOLX) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase HAMAP MF_01437
EC=2.7.8.5 HAMAP MF_01437
Alternative name(s):
Phosphatidylglycerophosphate synthase HAMAP MF_01437
Gene names
Name:pgsA HAMAP MF_01437 EMBL CAP76394.1
ORF Names:ECs2650 EMBL ACI81846.1, LF82_1635 EMBL CAP76394.1
OrganismEscherichia coli EMBL ACI81846.1
Taxonomic identifier562 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length182 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein catalyzes the committed step to the synthesis of the acidic phospholipids By similarity. HAMAP MF_01437

Catalytic activity

CDP-diacylglycerol + sn-glycerol 3-phosphate = CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate. HAMAP MF_01437

Pathway

Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2. HAMAP MF_01437

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP MF_01437.

Sequence similarities

Belongs to the CDP-alcohol phosphatidyltransferase class-I family. RuleBase RU003750 HAMAP MF_01437

Sequences

Sequence LengthMass (Da)Tools
C3T562 [UniParc].

Last modified June 16, 2009. Version 1.
Checksum: F8F0502ABE6DC8D5

FASTA18220,701
        10         20         30         40         50         60 
MQFNIPTLLT LFRVILIPFF VLVFYLPVTW SPFAAALIFC VAAVTDWFDG FLARRWNQST 

        70         80         90        100        110        120 
RFGAFLDPVA DKVLVAIAMV LVTEHYHSWW VTLPAATMIA REIIISALRE WMAELGKRSS 

       130        140        150        160        170        180 
VAVSWIGKVK TTAQMVALAW LLWRPNIWVE YAGIALFFVA AVLTLWSMLQ YLSAARADLL 


DQ

« Hide

References

[1]"A precise reconstruction of the emergence and constrained radiations of Escherichia coli O157 portrayed by backbone concatenomic analysis."
Leopold S.R., Magrini V., Holt N.J., Shaikh N., Mardis E.R., Cagno J., Ogura Y., Iguchi A., Hayashi T., Mellmann A., Karch H., Besser T.E., Sawyer S.A., Whittam T.S., Tarr P.I.
Proc. Natl. Acad. Sci. U.S.A. 106:8713-8718(2009) [PubMed: 19439656] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 493/89 EMBL ACI81846.1, 86-24 EMBL ACI81847.1, 87-14 EMBL ACI81848.1, TB182A EMBL ACI81849.1 and TW14359 EMBL ACI81850.1.
[2]"Complete genome sequence of adherent invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease."
Peyretaillade E., Claret L., Bonnet R., Dossat C., Barbe V., Vacherie B., Segurens B., Peyret P., Darfeuille-Michaud A.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: LF82 EMBL CAP76394.1.
[3]Genoscope - CEA
Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: LF82 EMBL CAP76394.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		EU899295 Genomic DNA. Translation: ACI81846.1.
EU899296 Genomic DNA. Translation: ACI81847.1.
EU899297 Genomic DNA. Translation: ACI81848.1.
EU899298 Genomic DNA. Translation: ACI81849.1.
EU899299 Genomic DNA. Translation: ACI81850.1.
CU651637 Genomic DNA. Translation: CAP76394.1.

3D structure databases

ProteinModelPortalC3T562.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC48653697. VBIEscCol74806_1906.

Family and domain databases

HAMAPMF_01437. PgsA.
[Tree]
InterProIPR000462. CDP-OH_P_trans.
IPR023762. PGP_synthase_bac.
IPR004570. Phosphatidylglycerol_P_synth.
[Graphical view]
PfamPF01066. CDP-OH_P_transf. 1 hit.
[Graphical view]
PIRSFPIRSF000847. Phos_ph_gly_syn. 1 hit.
TIGRFAMsTIGR00560. PgsA. 1 hit.
PROSITEPS00379. CDP_ALCOHOL_P_TRANSF. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC3T562_ECOLX
AccessionPrimary (citable) accession number: C3T562
Entry history
Integrated into UniProtKB/TrEMBL: June 16, 2009
Last sequence update: June 16, 2009
Last modified: January 25, 2012
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info