C3SEP3 (C3SEP3_ECOLX) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Mannonate dehydratase 1 HAMAP MF_00106
EC=4.2.1.8 HAMAP MF_00106

Alternative name(s):
D-mannonate hydrolase 1 HAMAP MF_00106

Gene names

Name:	uxuA1 HAMAP MF_00106
ORF Names:	ECs5281 EMBL ACI72947.1

Organism

Escherichia coli EMBL ACI72947.1

Taxonomic identifier

562 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. SAAS SAAS004628 HAMAP MF_00106
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. SAAS SAAS004628 HAMAP MF_00106
Sequence similarities	Belongs to the mannonate dehydratase family. HAMAP MF_00106

Ontologies

Keywords
Molecular function	Hydrolase EMBL ACI72947.1 Lyase SAAS SAAS004628 HAMAP MF_00106
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	hydrolase activity Inferred from electronic annotation. Source: UniProtKB-KW mannonate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C3SEP3 [UniParc]. Last modified June 16, 2009. Version 1. Checksum: 5C2CE5DB9599B735	FASTA	394	44,805
	10 20 30 40 50 60 MEQTWRWYGP NDPVSLADVR QAGATGVVTA LHHIPNGEVW SVEEILKRKA IVEDAGLVWS 70 80 90 100 110 120 VVESVPIHED IKTHTGNYEQ WIANYQQTLR NLAQCGIRTV CYNFMPVLDW TRTDLEYVLP 130 140 150 160 170 180 DGSKALRFDQ IEFAAFEMHI LKRPGAEADY TEEEIAQAAE RFATMSDEDK ARLTRNIIAG 190 200 210 220 230 240 LPGAEEGYTL DQFRKHLELY KDIDKAKLRE NFAVFLKAII PVAEEVGVRM AVHPDDPPRP 250 260 270 280 290 300 ILGLPRIVST IEDMQWMVDT VNSMANGFTM CTGSYGVRAD NDLVDMIKQF GPRIYFTHLR 310 320 330 340 350 360 STMREDNPKT FHEAAHLNGD VDMYEVVKAI VEEEHRRKAE GKEDLIPMRP DHGHQMLDDL 370 380 390 KKKTNPGYSA IGRLKGLAEV RGVELAIQRA FFSH

References

[1]

"A precise reconstruction of the emergence and constrained radiations of Escherichia coli O157 portrayed by backbone concatenomic analysis." Leopold S.R., Magrini V., Holt N.J., Shaikh N., Mardis E.R., Cagno J., Ogura Y., Iguchi A., Hayashi T., Mellmann A., Karch H., Besser T.E., Sawyer S.A., Whittam T.S., Tarr P.I. Proc. Natl. Acad. Sci. U.S.A. 106:8713-8718(2009) [PubMed: 19439656] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 86-24 EMBL ACI72947.1, 87-14 EMBL ACI72948.1 and TW14359 EMBL ACI72950.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EU890361 Genomic DNA. Translation: ACI72947.1. EU890362 Genomic DNA. Translation: ACI72948.1. EU890364 Genomic DNA. Translation: ACI72950.1.
3D structure databases
ProteinModelPortal	C3SEP3.
SMR	C3SEP3. Positions 1-389.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
HAMAP	MF_00106. UxuA. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
SUPFAM	SSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMs	TIGR00695. UxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C3SEP3_ECOLX

Accession

Primary (citable) accession number: C3SEP3

Entry history

Integrated into UniProtKB/TrEMBL:	June 16, 2009
Last sequence update:	June 16, 2009
Last modified:	May 31, 2011
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)